Research output per year
Research output per year
Personal profile
Research interests
My main interests lie in structural biology and biophysics, but I have recently become very interested in molecular dynamics simulations. Overall, the field of enzymology is my wider area of interest.
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Collaborations and top research areas from the last five years
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Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase
Tooke, C. L., Hinchliffe, P., Beer, M., Zinovjev, K., Colenso, C. K., Schofield, C. J., Mulholland, A. J. & Spencer, J., 5 Apr 2023, In: Journal of the American Chemical Society. 145, 13, p. 7166-7180 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)24 Downloads (Pure) -
QM/MM Simulations Reveal the Determinants of Carbapenemase Activity in Class A β-lactamases
Chudyk, E. I., Beer, M., Limb, M. A. L., Jones, C., Spencer, J., Van der Kamp, M. W. & Mulholland, A. J., 12 Aug 2022, In: ACS Infectious Diseases. 8, 8, p. 1521-1532 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile4 Citations (Scopus)30 Downloads (Pure) -
Tautomer-specific deacylation and Ω-loop flexibility explain carbapenem-hydrolyzing, broad-spectrum activity of the KPC-2 β-lactamase
Tooke, C. L., Hinchliffe, P., Beer, M., Zinovjev, K., Colenso, C. K., Schofield, C. J., Mulholland, A. J. & Spencer, J., 11 Nov 2022Research output: Other contribution