20042020

Research output per year

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Research Output

2020
Open Access
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31 Downloads (Pure)

Common variation at 16p11.2 is associated with glycosuria in pregnancy: Findings from a genome-wide association study in European women

Lee, M., McMahon, G., Karhunen, V., Wade, K. H., Corbin, L. J., Hughes, D. A., Davey Smith, G., Lawlor, D. A., Jarvelin, M-R. & Timpson, N. J., 15 Jun 2020, In : Human Molecular Genetics. 29, 12, p. 9 2098 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Downloads (Pure)
Open Access
File
87 Downloads (Pure)

Genome-wide associations of human gut microbiome variation and implications for causal inference analyses

Hughes, D. A., Bacigalupe, R., Wang, J., Rühlemann, M., Tito, R., Falony, G., Joossens, M., Vieira-Silva, S., Henckaerts, L., Rymenans, L., Verspecht, C., Ring, S. M., Franke, A., Wade, K. H., Timpson, N. J. & Raes, J., 22 Jun 2020, In : Nature Microbiology. 20 p.

Research output: Contribution to journalArticle (Academic Journal)

Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci

Mitchell, R. E., Dudding, T., Haworth, S., Timpson, N. J., Manousaki, D., Harroud, A., Forgetta, V., Shah, R. L., Luan, J., Langenberg, C. & Richards, B., 13 Feb 2020, In : American Journal of Human Genetics. 106, 3, p. 327-337

Research output: Contribution to journalArticle (Academic Journal)

Genome wide association study identifies genetic associations with perceived age

Roberts, V., Main, B., Timpson, N. J. & Haworth, S., 4 Mar 2020, (Accepted/In press) In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle (Academic Journal)

Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan

PRACTICAL Consortium, 24 Mar 2020, In : Nature Communications. 11, 1, p. 1536

Research output: Contribution to journalArticle (Academic Journal)

Heritability of Caries Scores, Trajectories and Disease Subtypes

Haworth, S., Esberg, A., Lif Holgerson, P., Kuja-Halkola, R., Timpson, N. J., Magnusson, P. K. E., Franks, P. W. & Johansson, I., 6 Jan 2020, In : Journal of Dental Research. 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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35 Downloads (Pure)

Metabolic characterisation of disturbances in the APOC3/triglyceride-rich lipoprotein pathway through sample-based recall by genotype

Corbin, L., Hughes, D. A., Chetwynd, A. J., Taylor, A. E., Southam, A. D., Ratcliffe, A., Jankevics, A., Weber, R. J. M., Groom, A., Dunn, W. B. & Timpson, N. J., 3 Jun 2020, In : Metabolomics. (2020) 16, 69, 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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30 Downloads (Pure)

Novel loci for childhood body mass index and shared heritability with adult 2 cardiometabolic traits

Timpson, N. J., Vogelezang, S., Stergiakouli, E., Davey Smith, G. & Freathy, R. M., 16 Mar 2020, (Accepted/In press) In : PLoS Genetics.

Research output: Contribution to journalArticle (Academic Journal)

Piloting the objective measurement of eating behaviour at a population-scale: a nested study within the Avon Longitudinal Study of Parents and Children

Wade, K. H., Clifford, L., Simpkin, A. J., Beynon, R. A., Birch, L., Northstone, K., Matthews, S. M., Davey Smith, G., Shield, J. P. H. & Timpson, N. J., 7 Oct 2020, (Submitted) In : Wellcome Open Research.

Research output: Contribution to journalArticle (Academic Journal)

The Dementias Platform UK (DPUK) Data Portal

Bauermeister, S., Ben-Shlomo, Y., Timpson, N. J. & al., E., 23 Apr 2020, In : European Journal of Epidemiology. 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Downloads (Pure)
2019
Open Access
File
38 Citations (Scopus)
282 Downloads (Pure)

Assessment of reproducibility and biological variability of fasting and postprandial plasma metabolite concentrations using 1H NMR spectroscopy

Li-Gao, R., Hughes, D. A., le Cessie, S., de Mutsert, R., den Heijer, M., Rosendaal, F. R., Willems van Dijk, K., Timpson, N. J. & Mook-Kanamori, D. O., 20 Jun 2019, In : PLoS ONE. 14, 6, 14 p., e0218549.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
92 Downloads (Pure)

Association between fat mass through adolescence and arterial stiffness: A population based study from The Avon Longitudinal Study of Parents and Children (ALSPAC)

Dangardt, F., Charakida, M., Georgiopoulos, G., Chiesa, S., Rapala, A., Wade, K., Hughes, A. D., Timpson, N., Pateras, K., Finer, N., Sattar, N., Davey Smith, G., Lawlor, D. & Deanfield, J., 1 Jul 2019, In : Lancet Child and Adolescent Health. 3, 7, p. 474-481 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
172 Downloads (Pure)

Associations of autozygosity with a broad range of human phenotypes

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M. & 416 others, Baumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J. F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-Salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M. L., Chen, G., Chen, Y. D. I., Chen, Z., Chiu, Y. F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., van Heel, D. A., Hirata, M., Höfer, I., Hsiung, C. A., Huang, J., Hung, Y. J., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K. T., Khor, C. C., de Kleijn, D. P. V., Koh, W. P., Kolcic, I., Kraft, P., Krämer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I. T., Lee, W. J., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A. W., Manunta, P., Másson, G., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P. E., Moreno-Macías, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., de Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Pálsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-Murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Sala, C. F., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-Khayat, B., Sennblad, B., van Setten, J., Sever, P. J., Sheu, W. H. H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stančáková, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y. C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusié-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Völker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J. M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., van den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C. Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C. K., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., De Jager, P. L., Johannesson, M., Johansson, Å., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., März, W., Matullo, G., McCarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-Kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O’connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., Den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E. S., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D. A., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T. Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 1 Dec 2019, In : Nature Communications. 10, 1, 17 p., 4957 (2019).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
77 Downloads (Pure)

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W. J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N. B., Lin, K. H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., 3 Jan 2019, In : American Journal of Human Genetics. 104, 1, p. 112-138 27 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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14 Citations (Scopus)
289 Downloads (Pure)

A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity

Bradfield, J. P., Vogelezang, S., Felix, J. F., Chesi, A., Timpson, N. & al., E., 5 Jul 2019, In : Human Molecular Genetics. 45 p., ddz161.

Research output: Contribution to journalEditorial (Academic Journal)

Open Access
File
1 Citation (Scopus)
5 Downloads (Pure)

Correction to: Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

Lawson, D. J., Davies, N. M., Haworth, S., Ashraf, B., Howe, L., Crawford, A., Hemani, G., Davey Smith, G. & Timpson, N. J., 30 Jul 2019, In : Human Genetics. 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Data Resource Profile: The ALSPAC birth cohort as a platform to study the relationship of environment and health and social factors

Boyd, A., Thomas, R., Hansell, A. L., Gulliver, J., Hicks, L. M., Griggs, R., Vande Hey, J., Taylor, C. M., Morris, T., Golding, J., Doerner, R., Fecht, D., Henderson, J., Lawlor, D. A., Timpson, N. J. & Macleod, J., 21 Apr 2019, In : International Journal of Epidemiology. 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
184 Downloads (Pure)

Determinants of intima-media thickness in the young: The Avon Longitudinal Study of Parents and Children (ALSPAC)

Chiesa, S. T., Charakida, M., Georgiopoulos, G., Dangardt, F., Wade, K. H., Rapala, A., Bhowruth, D., Nguyen, H., Muthurangu, V., Shroff, R., Davey Smith, G., Lawlor, D. A., Sattar, N., Timpson, N. J., Hughes, A. & Deanfield, J. E., 1 Oct 2019, In : JACC: Cardiovascular Imaging. 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
89 Downloads (Pure)

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

the 23 and Me Research Team, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, Demontis, D., Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., Belliveau, R., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Cerrato, F., Chambert, K., Churchhouse, C., Dumont, A., Eriksson, N., Gandal, M., Goldstein, J. I. & 33 others, Grasby, K. L., Grove, J., Gudmundsson, O. O., Hansen, C. S., Hauberg, M. E., Hollegaard, M. V., Howrigan, D. P., Huang, H., Maller, J. B., Martin, A. R., Martin, N. G., Moran, J., Pallesen, J., Palmer, D. S., Pedersen, C. B., Pedersen, M. G., Poterba, T., Poulsen, J. B., Ripke, S., Robinson, E. B., Satterstrom, F. K., Smith, G. D., Davies, G. E., Evans, D. M., Kemp, J. P., Ring, S., Stergiakouli, E., Pourcain, B. S., Stoltenberg, C., Timpson, N. J., Langley, K., Thapar, A. & Medland, S. E., 1 Jan 2019, In : Nature Genetics. 51, 1, p. 63-75 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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259 Citations (Scopus)
201 Downloads (Pure)

Ethnicity, heart failure, atrial fibrillation and diabetes: collider bias

Burden, A. F. & Timpson, N., 1 Jun 2019, In : Heart. 105, 11, p. 814-816 3 p.

Research output: Contribution to journalEditorial (Academic Journal)

2 Citations (Scopus)

GARFIELD classifies disease-relevant genomic features through integration of functional annotations with association signals

Lotchkova, V., Ritchie, G. R. S., Geihs, M., Morganella, S., Min, J., Walter, K., Timpson, N., Dunham, I., Birney, E., Soranzo, N. & UK10K Consortium, Feb 2019, In : Nature Genetics. 51, 2, p. 343-353 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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21 Citations (Scopus)
453 Downloads (Pure)
Open Access
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2 Citations (Scopus)
153 Downloads (Pure)

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

the 23 and Me Research Team, Dudding, T., Haworth, S., Lind, P. A., Sathirapongsasuti, J. F., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hicks, B., Hinds, D. A., Huber, K. E., Jewett, E. M., Jiang, Y., Kleinman, A., Lin, K. H. & 26 others, Litterman, N. K., McCeight, J. C., McIntyre, M. H., McManus, K. F., Mountain, J. L., Noblin, E. S., Northover, C. A. M., Pitts, S. J., Poznik, G. D., Shelton, J. F., Shringarpure, S., Tian, C., Vacic, V., Wang, X., Wilson, C. H., Tung, J. Y., Mitchell, R., Colodro-Conde, L., Medland, S. E., Gordon, S., Elsworth, B., Paternoster, L., Franks, P. W., Thomas, S. J., Martin, N. G. & Timpson, N. J., 5 Mar 2019, In : Nature Communications. 10, 12 p., 1052.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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7 Citations (Scopus)
203 Downloads (Pure)

Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data

Shungin, D., Haworth, S., Divaris, K., Agler, C., Kamatani, Y., Lee, M. K., Grinde, K., Hindy, G., Viivi Alaraudanjoki, V., Pesonen, P., Teumer, A., Holtfreter, B., Sakaue, S., Hirata, J., Yu, Y-H., Ridker, P., Giulianini, F., Chasman, D. I., Magnusson, P. K. E., Sudo, T. & 18 others, Okada, Y., Völker, U., Kocher, T., Anttonen, V., Laitala, M-L., Orho-Melander, M., Sofer, T., Shaffer, J. R., Vieira, A., Marazita, M. L., Kubo, M., Furuichi, Y., North, K., Offenbacher, S., Ingelsson, E., Franks, P. W., Timpson, N. & Johansson, I., 24 Jun 2019, In : Nature Communications. 10, 13 p., 2773.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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12 Citations (Scopus)
112 Downloads (Pure)

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child and adult BMI

Alves, A. C., De Silva, M., Karhunen, V., Sovio, U., Das, S., Taal, H. R., Warrington, N. M., Lewin, A., Kaakinen, M., Cousminer, D. L., Thiering, E., Timpson, N., Bond, T. A., Lowry, E., Brown, C., Estivill, X., Lindi, V., Bradfield, J. P., Geller, F., Speed, D. & 25 others, Coin, L. J. M., Loh, M., Barton, S. J., Beilin, L. J., Bisgaard, H., Bonnelykke, K., Alili, R., Hatoum, I., Schramm, K., Cartwright, R., Charles, M-A., Salerno, V., Clement, K., Claringbould, A., van Duijn, CM., Moltchanova, E., Frayling, T., Freathy, R., Lawlor, D., Ring, S., Davey Smith, G., McCarthy, M. I., Järvelin, M-R., Early Growth Genetics (EGG) Consortium & BIOS Consortium, 4 Sep 2019, In : Advances in Medical Sciences. 5, 9, 18 p., eaaw3095.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
132 Downloads (Pure)
Open Access
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11 Citations (Scopus)
256 Downloads (Pure)
Open Access
File
5 Citations (Scopus)
204 Downloads (Pure)

Is Population Structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

Lawson, D., Davies, N., Haworth, S., Ashraf, B., Howe, L., Crawford, A., Hemani, G., Davey Smith, G. & Timpson, N., 27 Apr 2019, In : Human Genetics. 19 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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182 Downloads (Pure)
Open Access
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3 Citations (Scopus)
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Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Haworth, S., Shapland, C. Y., Hayward, C., Prins, B. P., Felix, J. F., Medina-Gomez, C., Rivadeneira, F., Wang, C., Ahluwalia, T. S., Vrijheid, M., Guxens, M., Sunyer, J., Tachmazidou, I., Walter, K., Iotchkova, V., Jackson, A., Cleal, L., Huffmann, J., Min, J. L., Sass, L. & 7 others, Timmers, P. R. H. J., UK10K Consortium, Davey Smith, G., Cole, T. J., Timpson, N., Zeggini, E. & St Pourcain, B., 21 Jan 2019, In : Nature Communications. 10, 16 p., 357.

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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

EGG Consortium, May 2019, In : Nature Genetics. 51, 5, p. 804-814 11 p.

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35 Citations (Scopus)
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Morning plasma cortisol as a cardiovascular risk factor: Findings from prospective cohort and Mendelian randomization studies

Crawford, A., Söderberg, S., Kirschbaum, C., Murphy, L., Eliasson, M., Ebrahim, S., Davey Smith, G., Olsson, T., Sattar, N. A., Lawlor, D., Timpson, N., Reynolds, R. M. & Walker, B. R., 1 Oct 2019, In : European Journal of Endocrinology. 181, 4, p. 429 438 p.

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5 Citations (Scopus)
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Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Khera, A. V., Chaffin, M., Wade, K. H., Zahid, S., Brancale, J., Xia, R., Distefano, M., Senol-Cosar, O., Haas, M. E., Bick, A., Aragam, K. G., Lander, E. S., Smith, G. D., Mason-Suares, H., Fornage, M., Lebo, M., Timpson, N. J., Kaplan, L. M. & Kathiresan, S., 18 Apr 2019, In : Cell. 177, 3, p. 587-596.e9 20 p.

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64 Citations (Scopus)
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Prenatal alcohol exposure and offspring mental health: A systematic review

Easey, K., Dyer, M., Timpson, N. & Munafo, M., 1 Apr 2019, In : Drug and Alcohol Dependence. 197, p. 344-353 10 p.

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9 Citations (Scopus)
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The Avon Longitudinal Study of Parents and Children (ALSPAC): an update on the enrolled sample of index children in 2019

Northstone, K., Lewcock, M., Groom, A., Boyd, A., Macleod, J., Timpson, N. & Wells, N., 14 Mar 2019, In : Wellcome Open Research. 4, 10 p., 51.

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11 Citations (Scopus)
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The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortia: design, results and future prospects

Middeldorp, C. M., Felix, J. F., Mahajan, A., Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, Early Growth Genetics (EGG) Consortium, McCarthy, M. I. & Paternoster, L., Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300 22 p.

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Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Understanding Society Scientific Group, Giri, A., Hellwege, J. N., Keaton, J. M., Park, J., Qiu, C., Warren, H. R., Torstenson, E. S., Kovesdy, C. P., Sun, Y. V., Wilson, O. D., Robinson-Cohen, C., Roumie, C. L., Chung, C. P., Birdwell, K. A., Damrauer, S. M., DuVall, S. L., Klarin, D., Cho, K., Wang, Y. & 31 others, Evangelou, E., Cabrera, C. P., Wain, L. V., Shrestha, R., Mautz, B. S., Akwo, E. A., Sargurupremraj, M., Debette, S., Boehnke, M., Scott, L. J., Luan, J., Zhao, J-H., Willems, S. M., Thériault, S., Shah, N., Oldmeadow, C., Almgren, P., Li-Gao, R., Verweij, N., Boutin, T. S., Mangino, M., Ntalla, I., Feofanova, E., Surendran, P., Cook, J. P., Richardson, T. G., Zeggini, E., Scott, R. A., Palmer, C. N. A., Timpson, N. J. & Wilson, P. W. F., Jan 2019, In : Nature Genetics. 51, 1, p. 51-62 12 p.

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27 Citations (Scopus)
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2018

Age 23 years + oral health questionnaire in Avon Longitudinal Study of Parents and Children

Dudding, T., Haworth, S., Sandy, J. & Timpson, N. J., 30 Apr 2018, In : Wellcome Open Research. 3, 13 p., 34.

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Assessing the causal association between 25-hydroxyvitamin D and the risk of oral and oropharyngeal cancer using Mendelian randomization

Dudding, T., Johansson, M., Thomas, S. J., Brennan, P., Martin, R. M. & Timpson, N. J., 1 Sep 2018, In : International Journal of Cancer. 143, 5, p. 1029-1036 8 p.

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4 Citations (Scopus)
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Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses

Wade, K., Chiesa, S., Hughes, A. D., Chaturvedi, N., Charakida, M., Rapala, A., Muthurangu, V., Khan, T. A., Finer, N., Sattar, N., Howe, L., Fraser, A., Lawlor, D., Davey Smith, G., Deanfield, J. & Timpson, N., 30 Jul 2018, In : Circulation. 138, 20, 15 p.

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Associations of body mass and fat indexes with cardiometabolic traits

Bell, J., Carslake, D., O'Keeffe, L., Frysz, M., Howe, L., Hamer, M., Wade, K., Timpson, N. & Davey Smith, G., 18 Dec 2018, In : Journal of the American College of Cardiology. 72, 24, p. 3142-3154 13 p.

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13 Citations (Scopus)
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Associations of device-measured physical activity across adolescence with metabolic traits: Prospective cohort study

Bell, J., Hamer, M., Richmond, R., Timpson, N., Carslake, D. & Davey Smith, G., 11 Sep 2018, In : PLoS Medicine. 15, 9, 26 p., 1002649.

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5 Citations (Scopus)
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BMI and Mortality in UK Biobank: Revised Estimates Using Mendelian Randomization

Wade, K., Carslake, D., Sattar, N., Davey Smith, G. & Timpson, N., Nov 2018, In : Obesity. 26, 11, p. 1796-1806 11 p.

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Consortium-based genome-wide meta-analysis for childhood dental caries traits

Haworth, S., Shungin, D., van der Tas, J. T., Vucic, S., Medina-Gomez, C., Yakimov, V., Feenstra, B., Shaffer, J. R., Lee, M. K., Standl, M., Thiering, E., Wang, C., Bønnelykke, K., Waage, J., Eyrich Jessen, L., Nørrisgaard, P. E., Joro, R., Seppälä, I., Raitakari, O., Dudding, T. & 23 others, Grgic, O., Ongkosuwito, E., Vierola, A., Eloranta, A-M., West, N. X., Thomas, S. J., McNeil, D. W., Levy, S. M., Slayton, R., Nohr, E. A., Lehtimäki, T., Lakka, T., Bisgaard, H., Pennell, C., Kühnisch, J., Marazita, M. L., Melbye, M., Geller, F., Rivadeneira, F., Wolvius, E. B., Franks, P. W., Johansson, I. & Timpson, N. J., 20 Jun 2018, In : Human Molecular Genetics. 15 p., ddy237.

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Coronary Artery Disease, Genetic Risk and the Metabolome in Young Individuals

Battram, T., Hoskins, L., Hughes, D., Kettunen, J., Ring, S., Davey Smith, G., Timpson, N. & Ford, D., 12 Sep 2018, In : Wellcome Open Research. 3, 13 p., 114.

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3 Citations (Scopus)
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Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

Corbin, L. J., Tan, V. Y., Hughes, D. A., Wade, K. H., Paul, D. S., Tansey, K. E., Butcher, F., Dudbridge, F., Howson, J. M., Jallow, M. W., John, C., Kingston, N., Lindgren, C. M., O'Donavan, M., O'Rahilly, S., Owen, M. J., Palmer, C. N. A., Pearson, E. R., Scott, R. A., Van Heel, D. A. & 11 others, Whittaker, J., Frayling, T., Tobin, M. D., Wain, L. V., Smith, G. D., Evans, D. M., Karpe, F., McCarthy, M. I., Danesh, J., Franks, P. W. & Timpson, N. J., 19 Feb 2018, In : Nature Communications. 9, 1, 11 p., 711.

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