Projects per year
Nicky's research interests concern methodology for evidence synthesis, and use of evidence in decision modelling. This includes methods for synthesis of studies informing Markov model parameters, synthesis of evidence on components of complex interventions, bias adjustment in pairwise and network meta-analysis, allowing for uncertainty due to missing data, extrapolation of survival curves, and combining evidence with heterogeneously reported (but related) outcomes. She has also worked on methods and applications of Value of Information calculations that can be used to prioritise and design new research by comparing the expected benefit in the reduction of uncertainty in the optimal policy decision with the cost of a proposed new study. Nicky leads the Multi-Parameter Evidence Synthesis research group, is Director of the NICE Guidelines Technical Support Unit, associate editor for the journal Medical Decision Making, a Fellow of the Royal Statistical Society, and a member of the NICE Technology Appraisals Committee.
8071 MRC via York - HOD1: Inferring relative treatment effects from combined randomised and oberservational data
1/01/19 → 31/12/21
1/03/17 → 29/02/20
Baseline-Dependent Minimal Clinically Important Difference (MCID) for Depression and Anxiety: A Patient-Centred ApproachBauer-Staeb, C., Kounali, D-Z., Welton, N. J., Griffith, E., Wiles, N. J., Lewis, G., Faraway, J. J. & Button, K. S., 13 Apr 2021, (Accepted/In press) In: Journal of Clinical Epidemiology.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
Choice between implants in knee replacement: protocol for a Bayesian network meta-analysis, analysis of joint registries and economic decision model to determine the effectiveness and cost-effectiveness of knee implants for NHS patients-The KNee Implant Prostheses Study (KNIPS)Marques, E. M. R., Dennis, J., Beswick, A. D., Higgins, J., Thom, H., Welton, N., Burston, A., Hunt, L., Whitehouse, M. R. & Blom, A. W., 6 Jan 2021, In: BMJ Open. 11, 1, 11 p., e040205.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile10 Downloads (Pure)
Kennedy, P., Sumner, S., Botha, P., Welton, N. J., Higginson, A. D. & Radford, A. N., Apr 2021, In: Nature Ecology and Evolution. 5, 4, p. 468-479 12 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review1 Citation (Scopus)