20192020

Research output per year

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Personal profile

Research interests

My PhD is funded by the GW4 BioMed MRC DTP and I am supervised by Professor James Uney and Dr. Liang-Fong Wong at the University of Bristol, and Professor Nick Allen at Cardiff University. I am currently based within Professor Uney’s research group, within Translational Health Sciences.

My current research is in the cellular and molecular mechanisms of cell death in neurodegenerative diseases. I am particularly interested in Parkinson’s disease and polyglutamine disorders such as Huntington’s disease and the Spinocerebellar Ataxias. My PhD research has involved characterising mechanisms to improve mitochondrial health in neurodegenerative disease. I am also currently working on characterisation of novel roles of nucleic-acid binding proteins in the cell stress response in neurodegeneration.

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Research Output

  • 3 Article (Academic Journal)
Open Access
File
  • 23 Downloads (Pure)

    Dual druggable genome siRNA and compound screening approaches identify novel modulators of parkin recruitment to mitochondria

    Scott, H. L., Buckner, N., Fernandez-Albert, F., Pedone, E., Postiglione, L., Shi, G., Allen, N., Wong, L-F., Magini, L., Marucci, L., O’Sullivan, G., Cole, S., Powell, J., Maycox, P. & Uney, J. B., 7 Jan 2020, In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 92 Downloads (Pure)

    VEGFC reduces glomerular albumin permeability and protects against alterations in VEGF receptor expression in diabetic nephropathy

    Onions, K. L., Gamez, M., Buckner, N. R., Baker, S. L., Betteridge, K. B., Desideri, S., Dallyn, B. P., Ramnath, R. D., Neal, C. R., Farmer, L. K., Mathieson, P. W., Gnudi, L., Alitalo, K., Bates, D. O., Salmon, A. H. J., Welsh, G. I., Satchell, S. C. & Foster, R. R., Jan 2019, In : Diabetes. 68, 1, p. 172-187 16 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 11 Citations (Scopus)
    232 Downloads (Pure)

    Prizes

    Best PhD student presentation

    Buckner, Nikki R (Recipient), 6 Jul 2018

    Prize: Prizes, Medals, Awards and Grants

  • Supervised Work

    Investigating the role of RNA Binding Proteins and Modulators of Mitochondrial Function in Neurodegenerative Disease

    Author: Buckner, N. R., 23 Jun 2020

    Supervisor: Uney, J. (Supervisor) & Wong, L. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

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