Projects per year
Personal profile
Research interests
Dr Cordero-Llana’s research focuses on the processes underlying brain degeneration and the strategies of brain regeneration and repair. He is also a glia champion and determined to reduce the neuronal bias in neuroscience.
Dr Cordero-Llana graduated in Biochemistry from the University of Oviedo (Spain) in 2005. He then became a Fundesfor Scholar (a European Foundation for the Training and Development in Coal Mining Areas) which allowed him to move to the UK and obtain an MSc in Molecular Neuroscience at the University of Bristol in 2007. His research career started in the Stem Cells and Neuro-regeneration group working with human and rodent stem cells under the supervision of Prof Maeve Caldwell. He was then awarded a University of Bristol Scholarship to undertake a PhD investigating novel neurotrophic factors in neural stem cells and their application in neurodegenerative conditions. This work led to his first major funding - an Innovation Grant from Parkinson’s UK - to evaluate the efficacy of a new family of neurotrophic factors in preclinical models of Parkinson’s. In 2013, Dr Cordero-Llana joined the Molecular Neurodegeneration Group at the University of Oxford, where he worked towards the generation of novel animal models for the study of the molecular mechanisms that lead to motor neuron death in Amyotrophic Lateral Sclerosis (ALS). In 2015 Dr Cordero-Llana returned to Bristol to set up his own research group and lecture in Stem Cell Biology as Co-Director of the MSc in Stem Cells and Regeneration. Dr Cordero-Llana has been Postgraduate Research Director since 2020 and Associate Professor in Stem Cell Biology since 2023 in the department of Translational Health Sciences at the Bristol Medical School
External positions
Member, International Society for Stem Cell Research
2020 → …
Elected Committee Member Bristol Branch, Parkinson's UK
Mar 2016 → …
Keywords
- Neuron
- Astroctye
- Stem Cells
- Parkinson's
- miRNA
- Neurodegeneration
- Brain Repair
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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BBSRC ALERT 21 LCM-MM: Bringing Laser Capture Microscopy Technology to the University of Bristol
1/03/22 → 28/02/23
Project: Research, Parent
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BBSRC ALERT 21 LCM-MM: Bringing Laser Capture Microscopy Technology to the University of Bristol
1/03/22 → 28/02/23
Project: Research
Research output
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The miRNA transcriptome of cerebrospinal fluid in preterm infants reveals the signaling pathways that promote reactive gliosis following cerebral hemorrhage
Gialeli, A., Spaull, R., Plösch, T., Uney, J. B., Cordero Llana, O. & Heep, A., 18 Sept 2023, In: Frontiers in Molecular Neuroscience. 16, 1211373.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
AZD5438 a GSK-3a/b and CDK inhibitor is antiapoptotic modulates mitochondrial activity and protects human neurons from mitochondrial toxins
Shi, G., Scott, H., Azhar, N. I. F. M., Gialeli, A., Clennell, B., Lee, K. S., Hurcombe, J., Whitcomb, D., Coward, R., Wong, L-F., Cordero-Llana, O. & Uney, J. B., 23 May 2023, In: Scientific Reports. 13, 1, 13 p., 8334 (2023).Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Distinct regulation of hippocampal neuroplasticity and ciliary genes by corticosteroid receptors
Mifsud, K. R., Kennedy, C. L. M., Salatino, S., Sharma, E., Price, E. M., Haque, S. N., Gialeli, A., Goss, H. M., Panchenko, P. E., Broxholme, J., Engledow, S., Lockstone, H., Cordero Llana, O. & Reul, J. M. H. M., 6 Aug 2021, In: Nature Communications. 12, 1, 4737.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile19 Citations (Scopus)119 Downloads (Pure)
Prizes
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International Society for Stem Cell Research Travel Award
Cordero Llana, Oscar (Recipient), 2010
Prize: Prizes, Medals, Awards and Grants
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The Japan Neuroscience Society Travel Award
Cordero Llana, Oscar (Recipient), Jul 2018
Prize: Prizes, Medals, Awards and Grants
Activities
- 1 Participation in workshop, seminar, course
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Building your Academic Profile
Sarah Allsop (Speaker), Kathryn A Miller (Organiser), Zosia Beckles (Speaker), Peter Ibberson (Speaker) & Oscar Cordero Llana (Speaker)
3 Jul 2023Activity: Participating in or organising an event types › Participation in workshop, seminar, course
Thesis
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Tales of Neurotrophism : Neurotrophic Factors in Neural Stem Cells and the 6-OHDA Model of Parkinson's Disease
Author: Cordero Llana, O., 14 May 2013Supervisor: Caldwell, M. A. (Supervisor) & Wynick, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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