19962020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Review article (Academic Journal)
2018

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology

Horsburgh, K., Wardlaw, J. M., van Agtmael, T., Allan, S. M., Ashford, M. L. J., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Duncombe, J., Farr, T. D., Fowler, J. H., Goense, J., Granata, A., Hall, C. N., Hainsworth, A. H., Harvey, A., Hawkes, C. A., Joutel, A. & 20 others, Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., Macleod, M. R., Macrae, I. M., Markus, H. S., McCabe, C., McColl, B. W., Meakin, P. J., Miller, A., Nedergaard, M., Quinn, T. J., Rajani, R., Saksida, L. M., Touyz, R. M., Trueman, R. C., Wang, T. & Work, L. M., 30 Apr 2018, In : Clinical Science. 132, 8, p. 851-868 18 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
19 Citations (Scopus)
221 Downloads (Pure)

The coming of age of the angiotensin hypothesis in Alzheimer's disease: Progress toward disease prevention and treatment?

Kehoe, P. G., Mar 2018, In : Journal of Alzheimer's Disease. 62, 3, p. 1443-1466 24 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
21 Citations (Scopus)
242 Downloads (Pure)

Tools for testing decision-making capacity in dementia

Pennington, C., Davey, K., Coulthard, L., ter Meulen, R. & Kehoe, P., 11 Jul 2018, In : Age and Ageing. 7 p., afy096.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
6 Citations (Scopus)
110 Downloads (Pure)
2013

An exploration of the potential mechanisms and translational potential of five medicinal plants for applications in Alzheimer's disease

Shakir, T., Coulibaly, A. Y. & Kehoe, P. G., 2013, In : American Journal of Neurodegenerative Disease. 2, 2, p. 70-88 19 p.

Research output: Contribution to journalReview article (Academic Journal)

Current status of renin-aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease

Ashby, E. L. & Kehoe, P. G., Oct 2013, In : Expert Opinion on Investigational Drugs. 22, 10, p. 1229-1242 14 p.

Research output: Contribution to journalReview article (Academic Journal)

41 Citations (Scopus)

Therapeutic Benefits from Nanoparticles: The Potential Significance of Nanoscience in Diseases with Compromise to the Blood Brain Barrier

Krol, S., Macrez, R., Docagne, F., Defer, G., Laurent, S., Rahman, M., Hajipour, M. J., Kehoe, P. G. & Mahmoudi, M., Mar 2013, In : Chemical Reviews. 113, 3, p. 1877-1903 27 p.

Research output: Contribution to journalReview article (Academic Journal)

115 Citations (Scopus)
2012

Calcium Channel Blockers and Alzheimer's Disease: Potential Relevance in Treatment Strategies of Metabolic Syndrome

Goodison, W. V., Frisardi, V. & Kehoe, P. G., Feb 2012, In : Journal of Alzheimer's Disease. 30 Suppl 2, p. S269-S282 14 p.

Research output: Contribution to journalReview article (Academic Journal)

22 Citations (Scopus)

Drug repositioning for Alzheimer's disease

Corbett, A., Pickett, J., Burns, A., Corcoran, J., Dunnett, S. B., Edison, P., Hagan, J. J., Holmes, C., Jones, E., Katona, C., Kearns, I., Kehoe, P., Mudher, A., Passmore, A., Shepherd, N., Walsh, F. & Ballard, C., Nov 2012, In : Nature Reviews Drug Discovery. 11, 11, p. 833-846 14 p.

Research output: Contribution to journalReview article (Academic Journal)

147 Citations (Scopus)

Interdisciplinary challenges and promising theranostic effects of nanoscience in Alzheimer's disease

Laurent, S., Ejtehadi, M. R., Rezaei, M., Kehoe, P. G. & Mahmoudi, M., Mar 2012, In : RSC Advances. 2, 12, p. 5008-5033 26 p.

Research output: Contribution to journalReview article (Academic Journal)

38 Citations (Scopus)

The renin-angiotensin system and antihypertensive drugs in Alzheimer's disease: current standing of the angiotensin hypothesis?

Kehoe, P. G. & Passmore, P. A., 2012, In : Journal of Alzheimer's Disease. 30 Suppl 2, p. S251-S268 18 p.

Research output: Contribution to journalReview article (Academic Journal)

48 Citations (Scopus)
2011

Aβ-Degrading Enzymes: Potential for Treatment of Alzheimer Disease

Miners, J. S., Barua, N., Kehoe, P. G., Gill, S. & Love, S., Nov 2011, In : Journal of Neuropathology and Experimental Neurology. 70, 11, p. 944 - 959 17 p.

Research output: Contribution to journalReview article (Academic Journal)

170 Citations (Scopus)
2010

The molecular genetics of sirtuins: association with human longevity and age-related diseases

Polito, L., Kehoe, PG., Forloni, G. & Albani, D., Jun 2010, In : Int J Mol Epidemiol Genet. 1, p. 214 - 225 12 p.

Research output: Contribution to journalReview article (Academic Journal)

25 Citations (Scopus)
2009

Angiotensins and Alzheimer's disease: a bench to bedside overview

Kehoe, P. G., Jul 2009, In : Alzheimer's Research and Therapy. 1, 1, p. 3 1 p.

Research output: Contribution to journalReview article (Academic Journal)

Angiotensins in Alzheimer's disease - friend or foe?

Kehoe, PG., Miners, JS. & Love, S., Dec 2009, In : Trends in Neurosciences. 32, 12, p. 619 - 628 10 p.

Research output: Contribution to journalReview article (Academic Journal)

121 Citations (Scopus)

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy

Love, S., Miners, JS., Palmer, JC., Chalmers, KA. & Kehoe, PG., Jan 2009, In : Frontiers in Bioscience. 14, p. 4778 - 4792 15 p.

Research output: Contribution to journalReview article (Academic Journal)

52 Citations (Scopus)
2008

Abeta-degrading enzymes in Alzheimer's disease

Miners, J. S., Baig, S., Palmer, J., Palmer, L. E., Kehoe, P. G. & Love, S., Apr 2008, In : Brain Pathology. 18, 2, p. 240-52 13 p.

Research output: Contribution to journalReview article (Academic Journal)

292 Citations (Scopus)

Alzheimer Disease, Genetics of

Kehoe, P., 15 Sep 2008, In : Encyclopedia of Life Sciences.

Research output: Contribution to journalReview article (Academic Journal)

2007

Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?

Kehoe, P. G. & Wilcock, G. K., Apr 2007, In : Lancet Neurology. 6, 4, p. 373 - 378 6 p.

Research output: Contribution to journalReview article (Academic Journal)

143 Citations (Scopus)
2006

Current knowledge of chromosome 12 susceptibility genes for late-onset Alzheimer's disease

D'Introno, A., Solfrizzi, V., Colacicco, AM., Capurso, C., Amodio, M., Todarello, O., Capurso, A., Kehoe, PG. & Panza, F., Nov 2006, In : Neurobiology of Aging. 27 (11), p. 1537 - 1553 17 p.

Research output: Contribution to journalReview article (Academic Journal)

18 Citations (Scopus)

The Renin Angiotensin System in Alzheimer's disease: Do updates highlight a clinical and biological dichotomy?

Kehoe, PG. & Wilcock, GK., Apr 2006, In : Current Alzheimer Research. 3 (2), p. 171 - 173 3 p.

Research output: Contribution to journalReview article (Academic Journal)

5 Citations (Scopus)
2004

Vascular genetic factors and lipoprotein metabolism in human longevity

Panza, F., D'introno, A., Colacicco, AM., Basile, AM., Capurso, C., Kehoe, PG., Capurso, A. & Solfrizzi, V., Mar 2004, In : Mechanisms of Aging and Development. 125 (3), p. 169 - 178 10 p.

Research output: Contribution to journalReview article (Academic Journal)

37 Citations (Scopus)

Vascular risk and genetics of sporadic late-onset Alzheimer's disease

Panza, F., D'Introno, A., Colacicco, AM., Basile, AM., Capurso, C., Kehoe, PG., Capurso, A. & Solfrizzi, V., Jan 2004, In : Journal of Neural Transmission. 111 (1), p. 69 - 89 21 p.

Research output: Contribution to journalReview article (Academic Journal)

53 Citations (Scopus)
2003

Review: The renin-angiotensin-aldosterone system and Alzheimer's disease?

Kehoe, P. G., Jun 2003, In : Journal of the Renin-Angiotensin-Aldosterone-System. 4, 2, p. 80-93 14 p.

Research output: Contribution to journalReview article (Academic Journal)

32 Citations (Scopus)