20002020

Research output per year

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Research Output

  • 74 Article (Academic Journal)
  • 1 Book/Film/Article review (Academic Journal)
  • 1 Special issue (Academic Journal)
2020

The hallmarks of cancer are also the hallmarks of wound healing

Maccarthy-Morrogh, L. J. & Martin, P. B., 8 Sep 2020, In : Science Signaling. 13, 648, eaay8690.

Research output: Contribution to journalBook/Film/Article review (Academic Journal)

Open Access
File
23 Downloads (Pure)
2019

Cell migration by swimming: Drosophila adipocytes as a new in vivo model of adhesion-independent motility

Martin, P. B., Wood, W. J. & Franz, A., 4 Dec 2019, In : Seminars in Cell and Developmental Biology. 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Injury Activates a Dynamic Cytoprotective Network to Confer Stress Resilience and Drive Repair

Weavers, H., Wood, W. & Martin, P., 18 Nov 2019, In : Current Biology. 29, 22, p. 3851-3862.e4 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
148 Downloads (Pure)

Live imaging the foreign body response in zebrafish reveals how dampening inflammation reduces fibrosis

Gurevich, D. B., French, K. E., Collin, J. D., Cross, S. J. & Martin, P., 26 Sep 2019, In : Journal of Cell Science. 133, 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
77 Downloads (Pure)

Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation

Van Den Berg, M., MacCarthy-Morrogh, L., Carter, D., Morris, J., Ribeiro Bravo, I., Feng, Y. & Martin, P., 4 Jun 2019, In : Cell Reports. 27, 10, p. 2837-2846.e4 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
176 Downloads (Pure)

Specific macrophage populations promote both cardiac scar deposition and subsequent resolution in adult zebrafish

Bevan, L., Lim, Z. W., Venkatesh, B., Riley, P. R., Martin, P. & Richardson, R., 16 Aug 2019, In : Cardiovascular Research. 116, 7, 15 p., cvz221.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
134 Downloads (Pure)

The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin

Burzynski, L. C., Humphry, M., Pyrillou, K., Wiggins, K. A., Chan, J. N. E., Figg, N., Kitt, L. L., Summers, C., Tatham, K. C., Martin, P. B., Bennett, M. R. & Clarke, M. C. H., 16 Apr 2019, In : Immunity. 50, 4, p. 1033-1042.e6 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
28 Citations (Scopus)
217 Downloads (Pure)
2018

Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis

Greenhough, A., Bagley, C., Heesom, K., Gurevich, D., Gay, D., Bond, M., Collard, T., Paraskeva, C., Martin, P., Sansom, O. J., Malik, K. & Williams, A., Aug 2018, In : EMBO Molecular Medicine. 10, 8, 13 p., e8699.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
12 Citations (Scopus)
240 Downloads (Pure)

Drosophila immune cells extravasate from vessels to wounds using Tre1 GPCR and Rho signaling

Thuma, L., Carter, D., Weavers, H. & Martin, P., 3 Sep 2018, In : Journal of Cell Biology. 217, 9, 12 p., 3045.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
230 Downloads (Pure)

Fat Body Cells Are Motile and Actively Migrate to Wounds to Drive Repair and Prevent Infection

Franz, A., Wood, W. & Martin, P., 26 Feb 2018, In : Developmental Cell. 44, 4, p. 460-470.e3 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
24 Citations (Scopus)
228 Downloads (Pure)

Host-Biomaterial Interactions in Zebrafish

Witherel, C. E., Gurevich, D., Collin, J. D., Martin, P. & Spiller, K. L., 9 Apr 2018, In : ACS Biomaterials Science and Engineering. 4, 4, p. 1233-1240 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
289 Downloads (Pure)

Live imaging of collagen deposition during skin development and repair in a collagen I – GFP fusion transgenic zebrafish line

Morris, J., Cross, S., Lu, Y., Kadler, K. E., Lu, Y., Dallas, S. & Martin, P., 1 Sep 2018, In : Developmental Biology. 441, 1, p. 4-11 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
213 Downloads (Pure)

Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression

Gurevich, D., Severn, C., Twomey, C., Greenhough, A., Cash, J., Toye, A., Mellor, H. & Martin, P., 2 Jul 2018, In : EMBO Journal. 37, 13, 23 p., e97786.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
34 Citations (Scopus)
329 Downloads (Pure)

Long-term in vivo tracking of inflammatory cell dynamics within drosophila pupae

Weavers, H., Franz, A., Wood, W. & Martin, P., 14 Jun 2018, In : Journal of Visualized Experiments. 2018, 136, 10 p., e57871.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
222 Downloads (Pure)

Targeting miR-223 in neutrophils enhances the clearance of Staphylococcus aureus in infected wounds

de Kerckhove, M., Tanaka, K., Umehara, T., Okamoto, M., Kanematsu, S., Hayashi, H., Yano, H., Nishiura, S., Tooyama, S., Matsubayashi, Y., Komatsu, T., Park, S., Okada, Y., Takahashi, R., Kawano, Y., Hanawa, T., Iwasaki, K., Nozaki, T., Torigoe, H., Ikematsu, K. & 5 others, Suzuki, Y., Tanaka, K., Martin, P., Shimokawa, I. & Mori, R., 1 Oct 2018, In : EMBO Molecular Medicine. 10, 10, 21 p., e9024.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Citations (Scopus)
134 Downloads (Pure)
2017

Inflammation and metabolism in tissue repair and regeneration

Eming, S. A., Wynn, T. A. & Martin, P., 9 Jun 2017, In : Science. 356, 6342, p. 1026-12030 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
212 Citations (Scopus)
630 Downloads (Pure)

Macrophage Functions in Tissue Patterning and Disease: New Insights from the Fly

Wood, W. & Martin, P., 6 Feb 2017, In : Developmental Cell. 40, 3, p. 221-233 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
37 Citations (Scopus)
352 Downloads (Pure)

MiR-142 Is Required for Staphylococcus aureus Clearance at Skin Wound Sites via Small GTPase-Mediated Regulation of the Neutrophil Actin Cytoskeleton

Tanaka, K., Kim, S. E., Yano, H., Matsumoto, G., Ohuchida, R., Ishikura, Y., Araki, M., Araki, K., Park, S., Komatsu, T., Hayashi, H., Ikematsu, K., Tanaka, K., Hirano, A., Martin, P., Shimokawa, I. & Mori, R., Apr 2017, In : Journal of Investigative Dermatology. 137, 4, p. 931–940 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
15 Citations (Scopus)
215 Downloads (Pure)
2016

Accurate Reconstruction of Cell and Particle Tracks from 3D Live Imaging Data

Liepe, J., Sim, A., Weavers, H., Ward, L., Martin, P. & Stumpf, MP. H., 27 Jul 2016, In : Cell Systems. 3, 1, p. 102-107 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
275 Downloads (Pure)

Corpse engulfment generates a molecular memory that primes the macrophage inflammatory response

Weavers, H., Evans, I. R., Martin, P. & Wood, W., 16 Jun 2016, In : Cell. 165, 7, p. 1658-1671 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
76 Citations (Scopus)
466 Downloads (Pure)

Systems Analysis of the Dynamic Inflammatory Response to Tissue Damage Reveals Spatiotemporal Properties of the Wound Attractant Gradient

Weavers, H., Liepe, J., Sim, A., Wood, W., Martin, P. & Stumpf, MP. H., 8 Aug 2016, In : Current Biology. 26, 15, p. 1975-1989 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
23 Citations (Scopus)
376 Downloads (Pure)

Wound repair: a showcase for cell plasticity and migration

Shaw, T. J. & Martin, P., Oct 2016, In : Current Opinion in Cell Biology. 42, p. 29-37 9 p.

Research output: Contribution to journalSpecial issue (Academic Journal)

Open Access
File
73 Citations (Scopus)
293 Downloads (Pure)
2015

Ephrin-Bs Drive Junctional Downregulation and Actin Stress Fiber Disassembly to Enable Wound Re-epithelialization

Nunan, R., Campbell, J., Mori, R., Pitulescu, M. E., Jiang, W. G., Harding, K. G., Adams, R. H., Nobes, C. D. & Martin, P. B., 17 Nov 2015, In : Cell Reports. 13, 7, p. 1380–1395 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
27 Citations (Scopus)
326 Downloads (Pure)

Imaging innate immune responses at tumour initiation: new insights from fish and flies

Feng, Y. & Martin, P., Sep 2015, In : Nature Reviews Cancer. 15, 9, p. 556-62 7 p.

Research output: Contribution to journalArticle (Academic Journal)

27 Citations (Scopus)

The wound inflammatory response exacerbates growth of pre-neoplastic cells and progression to cancer

Antonio, N., Bønnelykke-Behrndtz, M. L., Ward, L. C., Collin, J., Christensen, I. J., Steiniche, T., Schmidt, H., Feng, Y. & Martin, P., 2 Sep 2015, In : EMBO Journal. 34, 17, p. 2219-2236 18 p.

Research output: Contribution to journalArticle (Academic Journal)

80 Citations (Scopus)
2014

Clinical challenges of chronic wounds: searching for an optimal animal model to recapitulate their complexity

Nunan, R., Harding, K. G. & Martin, P., Nov 2014, In : Disease Models and Mechanisms. 7, 11, p. 1205-13 9 p.

Research output: Contribution to journalArticle (Academic Journal)

127 Citations (Scopus)

Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation

Razzell, W., Wood, W. & Martin, P., May 2014, In : Development (Cambridge). 141, 9, p. 1814-1820 7 p.

Research output: Contribution to journalArticle (Academic Journal)

41 Citations (Scopus)

Reduced FOXO1 Expression Accelerates Skin Wound Healing and Attenuates Scarring

Mori, R., Tanaka, K., de Kerckhove, M., Okamoto, M., Kashiyama, K., Tanaka, K., Kim, S., Kawata, T., Komatsu, T., Park, S., Ikematsu, K., Hirano, A., Martin, P. & Shimokawa, I., Sep 2014, In : American Journal of Pathology. 184, 9, p. 2465-79 15 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)

Resolution mediator chemerin15 reprograms the wound microenvironment to promote repair and reduce scarring

Cash, J. L., Bass, M. D., Campbell, J., Barnes, M., Kubes, P. & Martin, P. B., 16 Jun 2014, In : Current Biology. 24, 12, p. 1406-14 9 p.

Research output: Contribution to journalArticle (Academic Journal)

31 Citations (Scopus)

Wound repair and regeneration: Mechanisms, signaling, and translation

Eming, S. A., Martin, P. & Tomic-Canic, M., 3 Dec 2014, In : Science Translational Medicine. 6, 265, p. 265sr6

Research output: Contribution to journalArticle (Academic Journal)

692 Citations (Scopus)
2013

Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release

Razzell, W., Evans, I. R., Martin, P. & Wood, W. J., 4 Mar 2013, In : Current Biology. 23, 5, p. 424-9 6 p.

Research output: Contribution to journalArticle (Academic Journal)

163 Citations (Scopus)

Inflammation drives wound hyperpigmentation in zebrafish by recruiting pigment cells to sites of tissue damage

Lévesque, M., Feng, Y., Jones, R. A. & Martin, P., Mar 2013, In : Disease Models and Mechanisms. 6, 2, p. 508-15 8 p.

Research output: Contribution to journalArticle (Academic Journal)

37 Citations (Scopus)

Modelling of human Wiskott-Aldrich syndrome protein mutants in zebrafish larvae using in vivo live imaging

Jones, R. A., Feng, Y., Worth, A. J., Thrasher, A. J., Burns, S. O. & Martin, P., 15 Sep 2013, In : Journal of Cell Science. 126, Pt 18, p. 4077-84 8 p.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing

Smart, N., Dubé, K. N., Bollini, S., Evans, H. G., Taams, L. S., Richardson, R., Lévesque, M., Martin, P., Mills, K., Riegler, J., Price, A. N., Lythgoe, M. F. & Riley, P. R., 2013, In : Nature Communications. 4, p. 2081

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)
2012

Embryonic clutch control

Razzell, W. & Martin, P., Mar 2012, In : Science. 335(#6073), p. 1181 - 1182 2 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)

Knockdown of osteopontin reduces the inflammatory response and subsequent size of postsurgical adhesions in a murine model.

Andrews, S. N., Ford, D. J. & Martin, P. B., 2012, In : American Journal of Pathology. 181, 4, p. 1165-1172

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)

Live imaging of tumor initiation in zebrafish larvae reveals a trophic role for leukocyte-derived PGE₂.

Feng, Y., Renshaw, S. & Martin, P. B., May 2012, In : Current Biology. 22, 13, p. 1253-1259 7 p.

Research output: Contribution to journalArticle (Academic Journal)

56 Citations (Scopus)
7 Citations (Scopus)
2011

A Syndecan-4 hair trigger initiates wound healing through Caveolin- and RhoG-regulated integrin endocytosis

Bass, M. D., Williamson, R. C., Nunan, R. D., Humphries, J. D., Byron, A., Morgan, M. R., Martin, P. & Humphries, M. J., Oct 2011, In : Developmental Cell. 21, 5, p. 681 - 693 13 p.

Research output: Contribution to journalArticle (Academic Journal)

85 Citations (Scopus)

Microtubule remodelling is required for the front-rear polarity switch during contact inhibition of locomotion

Kadir, S., Astin, J. W., tahtamouni, L., Martin, P. & Nobes, C. D., Apr 2011, In : Journal of Cell Science. 124, p. 2642 - 2653 12 p.

Research output: Contribution to journalArticle (Academic Journal)

42 Citations (Scopus)

Swatting flies: modelling wound healing and inflammation in Drosophila

Razzell, W., Wood, W. & Martin, P., Sep 2011, In : Disease Models and Mechanisms. 4, 5, p. 569 - 574 6 p.

Research output: Contribution to journalArticle (Academic Journal)

53 Citations (Scopus)

White wave analysis of epithelial scratch wound healing reveals how cells mobilise back from the leading edge in a myosin-II-dependent fashion

Matsubayashi, Y., Razzel, W. & Martin, P., Apr 2011, In : Journal of Cell Science. 24 (7), p. 1017 - 1021 5 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)
2010

Clasp-mediated microtubule bundling regulates persistent motility and contact repulsion in Drosophila macrophages in vivo

Stramer, B., Moreira, S., Millard, T., Evans, I., Huang, C-Y., Sabet, O., Milner, M., Dunn, G., Martin, P. & Wood, W., 17 May 2010, In : Journal of Cell Biology. 189, 4, p. 681 - 689 9 p., S1 - S4.

Research output: Contribution to journalArticle (Academic Journal)

84 Citations (Scopus)

Fascin is required for blood cell migration during Drosophila embryogenesis

Zanet, J., Stramer, B., Millard, T., Martin, P., Payre, F. & Plaza, S., Aug 2010, In : Development (Cambridge). 136 (15), p. 2557 - 2565 9 p.

Research output: Contribution to journalArticle (Academic Journal)

48 Citations (Scopus)

Live imaging of innate immune cell sensing of transformed cells in zebrafish larvae: Parallels between tumor initiation and wound inflammation

Feng, Y., Santoriello, C., Mione, M., Hurlstone, A. & Martin, P., Dec 2010, In : PLoS Biology. 8, 12, p. 1-19 19 p., e1000562.

Research output: Contribution to journalArticle (Academic Journal)

131 Citations (Scopus)

Prioritization of Competing Damage and Developmental Signals by Migrating Macrophages in the Drosophila Embryo

Moreira, S., Stramer, B., Evans, I., Wood, W. & Martin, P., 9 Mar 2010, In : Current Biology. 20, 5, p. 464 - 470 7 p.

Research output: Contribution to journalArticle (Academic Journal)

131 Citations (Scopus)
2009

Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes

Shaw, T. & Martin, P., Aug 2009, In : EMBO Reports. 10 (8), p. 881 - 886 6 p.

Research output: Contribution to journalArticle (Academic Journal)

112 Citations (Scopus)

Inflammation: Wound healing in zebrafish

Martin, P. & Feng, Y., 18 Jun 2009, In : Nature. 459, 7249, p. 921-3 3 p.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

Wound repair at a glance

Shaw, TJ. & Martin, P., Sep 2009, In : Journal of Cell Science. 122 (18), p. 3209 - 3213 5 p.

Research output: Contribution to journalArticle (Academic Journal)

377 Citations (Scopus)
2008

Analysis of WASp function during the wound inflammatory response - live-imaging studies in zebrafish larvae

Cvejic, A., Hall, C., Bak-Maier, M., Flores, MV., Crosier, P., Redd, MJ. & Martin, P., Oct 2008, In : Journal of Cell Science. 121 (19), p. 3196 - 3206 11 p.

Research output: Contribution to journalArticle (Academic Journal)

48 Citations (Scopus)