Personal profile
Research interests
Dr Paul Madley-Dowd is a statistician and epidemiologist specialising in target trials, causal inference, and analysis methods to handle missing data in observational research. His research focuses on developing and applying robust methodological approaches to draw valid causal conclusions from complex health data. His recent methodological contributions include guidance on the use of multiple imputation and the role of auxiliary variables in reducing bias, and the development of directed acyclic graph–based methods to determine when multiple imputation produces unbiased exposure–outcome estimates.
He completed his PhD at the University of Bristol, where his doctoral research investigated whether relationships between maternal exposures and offspring outcomes were likely to reflect causal effects using advanced epidemiologic methods. Since then, Paul has continued his academic career within Bristol Medical School. Paul teaches and collaborates across interdisciplinary teams, contributing to courses and seminars on causal inference and epidemiologic methods. His broader goal is to enhance how causal questions are answered in population health research, improving the reliability and interpretability of evidence that informs clinical practice and policy.
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Collaborations and top research areas from the last five years
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Childhood trauma as a mediator between autistic traits and depression: Evidence from the ALSPAC birth cohort
Underwood, J. F. G., Madley-Dowd, P. C., Dardani, C., Hull, L., Kwong, A. S. F., Pearson, R. M., Hall, J. & Rai, D., 29 May 2026, In: Psychological Medicine. 56, 14 p., e169.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access10 Downloads (Pure) -
Effectiveness of bivalent BA.1 mRNA booster vaccines during the autumn 2022 COVID-19 booster programme in adults aged 50+ in England: observational matched cohort study using OpenSAFELY
Madley-Dowd, P. C., Horne, E. M. F., Hulme, W. J., Palmer, T. M., Walker, V. M., Denholm, R. E. & Sterne, J. A. C., 18 Feb 2026, (E-pub ahead of print) In: Vaccine. 76, p. 128276 12 p., 128276.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Lithium prescribing in the perinatal period: UK primary care cohort study
Chauhan, D., Madley-Dowd, P., Hayes, J. F., Rast, J. E., Ahlqvist, V. H., Martin, F. Z., Magnusson, C., Rai, D. & Lee, B. K., 17 Apr 2026, (E-pub ahead of print) In: The British Journal of Psychiatry. p. 1-7 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access
Projects
- 1 Active
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Anti-seizure medication prescription during preconception period and pregnancy with risk of orofacial clefts in offspring: A UK CPRD GOLD population-based study
Jain, K. (Student), Madley-Dowd, P. C. (Collaborator), Lewis, S. J. (Collaborator) & Davies, A. J. V. (Collaborator)
1/06/22 → …
Project: Research
Thesis
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Assessing causality of the association between maternal smoking during pregnancy and offspring intellectual disability
Madley-Dowd, P. C. (Author), Rai, D. (Supervisor), Zammit, S. (Supervisor) & Heron, J. E. (Supervisor), 23 Mar 2021Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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