Dr Penny F Whiting

B.A.(Oxon.), M.Sc.(Lond.), Ph.D.(Amst.)

  • BS8 2PS

20012020

Research output per year

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Research Output

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Article (Academic Journal)
2020

Agreement was moderate between data-based and opinion-based predictions of biases affecting randomized trials within meta-analyses

Turner, R. M., Rhodes, K. M., Jones, H. E., Higgins, J. P. T., Haskins, J., Whiting, P. F., Hróbjartsson, A., Caldwell, D. M., Morris, R. W., Reeves, B. C., Worthington, H., Boutron, I. & Savović, J., 13 May 2020, In : Journal of Clinical Epidemiology. 125, p. 16-25 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Practice pointer: Interpreting a covid-19 test result

Watson, J., Whiting, P. F. & Brush, J. E., 12 May 2020, In : BMJ. 2020, 7 p., 369.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
72 Downloads (Pure)

The Preferred Reporting Items for Systematic Review and Meta-Analysis of Diagnostic Test Accuracy studies (PRISMA-DTA): Explanation, Elaboration and Checklist

Salameh, J-P., Bossuyt, P. N. M., McGrath, T. A., Thombs, B. D., Hyde, C. J., Deeks, J. J., Leeflang, M., Korevaar, D. A., Whiting, P. F., Takwoingi, Y., Reitsma, J. B., Cohen, J. F., Frank, R., Hunt, H. A., Hooft, L., Rutjes, A. W. S., Willis, B. H., Gatsonis, C., Levis, B., Moher, D. & 1 others, McInnes, M. D. F., 20 May 2020, (Accepted/In press) In : BMJ.

Research output: Contribution to journalArticle (Academic Journal)

2019

Added value and cascade effects of inflammatory marker tests in UK primary care: a cohort study from the Clinical Practice Research Datalink

Watson, J., Salisbury, C., Whiting, P., Banks, J., Pyne, Y. & Hamilton, W., 1 Jul 2019, In : British Journal of General Practice. 69, 684, p. e470-e478 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
180 Downloads (Pure)

Comparison of multiparametric magnetic resonance imaging and targeted biopsy with systematic biopsy alone for the diagnosis of prostate cancer: a systematic review and meta-analysis

Elwenspoek, M. M. C., Sheppard, A. L., McInnes, M. D. F., Merriel, S. W. D., Rowe, E. W. J., Bryant, R. J., Donovan, J. L. & Whiting, P., 7 Aug 2019, In : JAMA Network Open. 2, 8, 13 p., e198427.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
93 Downloads (Pure)

Digital Education in Health Professions: The Need for Overarching Evidence Synthesis

Car, J., Carlstedt-Duke, J., Tudor Car, L., Posadzki, P., Whiting, P., Zary, N., Atun, R., Majeed, A., Campbell, J. & Digital Health Education Collaboration, Feb 2019, In : JMIR. 21, 2, 11 p., e12913.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
21 Citations (Scopus)
143 Downloads (Pure)

Distributions of the National Early Warning Score (NEWS) across a healthcare system following a large-scale roll-out

Scott, L. J., Redmond, N. M., Garrett, J., Whiting, P., Northstone, K. & Pullyblank, A., 1 May 2019, In : Emergency Medicine Journal. 36, 5, p. 287-292 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
246 Downloads (Pure)

Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records

Watson, J., Salisbury, C., Banks, J., Whiting, P. & Hamilton, W., 28 May 2019, In : British Journal of Cancer. 120, 11, p. 1045-1051 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
448 Downloads (Pure)

PROBAST: A Tool to Assess the Risk of Bias and Applicability of Prediction Model Studies

PROBAST Group†, 1 Jan 2019, In : Annals of Internal Medicine. 170, 1, p. 51-58 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
81 Citations (Scopus)
200 Downloads (Pure)

RoB 2: a revised tool for assessing risk of bias in randomised trials

Sterne, J. A. C., Savović, J., Page, M. J., Elbers, R. G., Blencowe, N. S., Boutron, I., Cates, C. J., Cheng, H-Y., Corbett, M. S., Eldridge, S. M., Emberson, J. R., Hernán, M. A., Hopewell, S., Hróbjartsson, A., Junqueira, D. R., Juni, P., Kirkham, J. J., Lasserson, T., Li, T., McAleenan, A. & 8 others, Reeves, B. C., Shepperd, S., Shrier, I., Stewart, L. A., Tilling, K., White, I. R., Whiting, P. F. & Higgins, J. P. T., 28 Aug 2019, In : BMJ. 366, 8 p., l4898.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
297 Citations (Scopus)
227 Downloads (Pure)

Systematic review of interventions for the prevention and treatment of postoperative urinary retention

Jackson, J., Davies, P., Leggett, N., Nugawela Pathirannehelage, M., Scott, L., Leach, V., Richards, A., Blacker, A., Abrams, P., Sharma, J., Donovan, J. & Whiting, P., Feb 2019, In : BJS Open. 3, 1, p. 11-23 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
219 Downloads (Pure)

The utility of diagnostic selective nerve root blocks in the management of patients with lumbar radiculopathy: A systematic review

Beynon, R., Elwenspoek, M., Sheppard, A., Higgins, N., Kolias, A., Laing, R., Whiting, P. & Hollingworth, W., 20 Apr 2019, In : BMJ Open. 9, 4, p. e025790 9 p., e025790.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
179 Downloads (Pure)

Use of multiple inflammatory marker tests in primary care: using Clinical Practice Research Datalink to evaluate accuracy

Watson, J., Jones, H., Banks, J., Whiting, P., Salisbury, C. & Hamilton, W., 1 Jul 2019, In : British Journal of General Practice. 69, 684, p. e462-e469 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
183 Downloads (Pure)
2018

Early warning scores do not accurately predict mortality in sepsis: a meta-analysis and systematic review of the literature

Hamilton, F., Arnold, D., Baird, A., Albur, M. & Whiting, P., Mar 2018, In : Journal of Infection. 76, 3, p. 241-248 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
272 Downloads (Pure)
Open Access
File
2 Citations (Scopus)
239 Downloads (Pure)

Guidance was developed on how to write a plain language summary for diagnostic test accuracy reviews

Whiting, P., Leeflang, M., de Salis, I., Mustafa, R. A., Santesso, N., Gopalakrishna, G., Cooney, G., Jesper, E., Thomas, J. & Davenport, C., 1 Nov 2018, In : Journal of Clinical Epidemiology. 103, p. 112-119 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
234 Downloads (Pure)

Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies: The PRISMA-DTA Statement

McInnes, M. D. F., Moher, D., Thombs, B. D., McGrath, T. A., Bossuyt, P. M., Clifford, T., Cohen, J. F., Deeks, J. J., Gatsonis, C., Hooft, L., Hunt, H. A., Hyde, C. J., Korevaar, D. A., Leeflang, M. M. G., Macaskill, P., Reitsma, J. B., Rodin, R., Rutjes, A. W. S., Salameh, J. P., Stevens, A. & 6 others, Takwoingi, Y., Tonelli, M., Weeks, L., Whiting, P., Willis, B. H. & PRISMA-DTA Group, Jan 2018, In : JAMA - Journal of the American Medical Association. 319, 4, p. 388-396 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
337 Citations (Scopus)
312 Downloads (Pure)

Quality of family relationships and outcomes of dementia: a systematic review

Edwards, H., Ijaz, S., Whiting, P., Leach, V., Richards, A., Cullum, S., Richard, C. & Savović, J., Jan 2018, In : BMJ Open. 8, 1, 14 p., e015538.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
223 Downloads (Pure)

Understanding test accuracy research: a test consequence graphic

Whiting, P. & Davenport, C., 18 Jan 2018, In : Diagnostic and Prognostic Research. 2, 5 p., 2.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
244 Downloads (Pure)

Use of emergency contraception among women with experience of domestic violence and abuse: a systematic review

Lewis, N. V., Moore, T. H. M., Feder, G. S., Macleod, J. & Whiting, P., 25 Sep 2018, In : BMC Women's Health. 18, 8 p., 156.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
227 Downloads (Pure)
2017

Accuracy of cystatin C for the detection of abnormal renal function in children undergoing chemotherapy for malignancy: a systematic review using individual patient data

Whiting, P., Birnie, K., Sterne, J., Jameson, C., Skinner, R., Phillips, B., Barnfield, M., Blufpand, H., Bokenkamp, A., Grönroos, M., Jameson, C., Lankisch, P., Philips, B., Skinner, R., Sterne, J., Whiting, P. & The Cystatin C In Childhood Cancer Collaboration Group, 6 Dec 2017, In : Supportive Care in Cancer. p. 1-10 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
206 Downloads (Pure)

A proposed framework for developing quality assessment tools

Whiting, P., Wolff, R. F., Mallett, S., Simera, I. & Savović, J., 17 Oct 2017, In : Systematic Reviews. 6, 9 p., 204.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Citations (Scopus)
227 Downloads (Pure)

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: diagnostic cohort study

Birnie, K., Hay, A., Wootton, M., Howe, R. A., MacGowan, A. P., Whiting, P., Lawton, M., Delaney, B., Downing, H., Dudley, J. A., Hollingworth, W., Lisles, C., Little, P., O'Brien, K., Pickles, T., Rumsby, K., Thomas-Jones, E., Van Der Voort, J., Waldron, C-A., Harman, K. & 3 others, Hood, K., Butler, C. C. & Sterne, J., 15 Feb 2017, In : PLoS ONE. 12, 2, 13 p., e0171113.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
302 Downloads (Pure)

Erratum to: Methods for evaluating medical tests and biomarkers

STREAMLINE COLON Investigators, 30 Mar 2017, In : Diagnostic and Prognostic Research. 1, p. 11

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
21 Downloads (Pure)

Models to predict relapse in psychosis: A systematic review

Sullivan, S., Northstone, K., Gadd, C., Walker, J., Margelyte, R., Richards, A. C. & Whiting, P., 21 Sep 2017, In : PLoS ONE. 12, 9, 12 p., e0183998.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
221 Downloads (Pure)

Predictive values of referrals for transient ischaemic attack from first-contact health care: a systematic review

Kandiyali, R., Lasserson, D. S., Whiting, P., Richards, A. & Mant, J., Dec 2017, In : British Journal of General Practice. 67, 665, p. e871-e880 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
201 Downloads (Pure)

What are the risks and benefits of temporarily discontinuing medications to prevent acute kidney injury? A systematic review and meta-analysis

Whiting, P., Savović, J., Morden, A., Caskey, F., Blakeman, T., Tomson, C., Stone, T., Richards, A., Horwood, J. & Tomlinson, L., Apr 2017, In : BMJ Open. 7, 4, 10 p., e012674.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
25 Citations (Scopus)
306 Downloads (Pure)
2016

Quality of relationships as predictors of outcomes in people with dementia: a systematic review protocol

Edwards, H. B., Savovic, J., Whiting, P. F., Leach, V. A., Richards, A. C., Cullum, S. J. & Cheston, R., 4 Apr 2016, In : BMJ Open. 6, 4, 6 p., e010835.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
246 Downloads (Pure)

ROBINS-I: a tool for assessing risk of bias in non-randomized studies of interventions

Sterne, J., Hernán, M. A., Reeves, B., Savović, J., Berkman, N. D., Viswanathan, M., Henry, D., Altman, D. G., Ansari, M. T., Boutron, I., Carpenter, J. R., Chan, A-W., Churchill, R., Deeks, J. J., Hróbjartsson, A., Kirkham, J., Juni, P., Loke, Y. K., Pigott, T. D., Ramsay, C. R. & 14 others, Regidor, D., Rothstein, H. R., Sandhu, L., Schünemann, H., Shea, B., Shrier, I., Tugwell, P., Turner, L., Valentine, J. C., Waddington, H., Waters, E., Wells, G. A., Whiting, P. & Higgins, J., 12 Oct 2016, In : BMJ. 355, 7 p., i4919.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1652 Citations (Scopus)
425 Downloads (Pure)

ROBIS: A new tool to assess risk of bias in systematic reviews was developed

Whiting, P. F., Savovic, J., Higgins, J. P. T., Caldwell, D. M., Reeves, B. C., Shea, B., Davies, P., Kleijnen, J., Churchill, R. C. & ROBIS Group, Jan 2016, In : Journal of Clinical Epidemiology. 69, p. 225-324 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
339 Citations (Scopus)
719 Downloads (Pure)

Standardizing and monitoring the delivery of surgical interventions in randomized clinical trials

Blencowe, N., Blazeby, J., Whiting, P., Mills, N., Cook, J., Donovan, J. & Rogers, C., Sep 2016, In : British Journal of Surgery. 103, 10, p. 1377-1384 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
380 Downloads (Pure)

The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness

Hay, A. D., Birnie, K., Busby, J., Delaney, B., Downing, H., Dudley, J., Durbaba, S., Fletcher, M., Harman, K., Hollingworth, W., Hood, K., Howe, R., Lawton, M., Lisles, C., Little, P., MacGowan, A., O'Brien, K., Pickles, T., Rumsby, K., Sterne, J. A. & 6 others, Thomas-Jones, E., van der Voort, J., Waldron, C-A., Whiting, P., Wootton, M. & Butler, C. C., 12 Jul 2016, In : Health Technology Assessment. 20, 51, p. 1-294 294 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
19 Citations (Scopus)
348 Downloads (Pure)
2015

Cannabinoids for Medical Use: A Systematic Review and Meta-analysis

Whiting, P. F., Wolff, R. F., Deshpande, S., Di Nisio, M., Duffy, S., Hernandez, A. V., Keurentjes, J. C., Lang, S., Misso, K., Ryder, S., Schmidlkofer, S., Westwood, M. & Kleijnen, J., 24 Jun 2015, In : JAMA - Journal of the American Medical Association. 313, 24, p. 2456-2473 18 p.

Research output: Contribution to journalArticle (Academic Journal)

784 Citations (Scopus)

High-sensitivity troponin assays for the early rule-out or diagnosis of acute myocardial infarction in people with acute chest pain: a systematic review and cost-effectiveness analysis

Westwood, M., van Asselt, T., Ramaekers, B., Whiting, P., Thokala, P., Joore, M., Armstrong, N., Ross, J., Severens, J. & Kleijnen, J., Jun 2015, In : Health Technology Assessment. 19, 44, p. 1-234 234 p.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)

How well do health professionals interpret diagnostic information? A systematic review

Whiting, P. F., Davenport, C., Jameson, C., Burke, M., Sterne, J. A. C., Hyde, C. & Ben-Shlomo, Y., Jul 2015, In : BMJ Open. 5, 7, 8 p., e008155.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
33 Citations (Scopus)
365 Downloads (Pure)

Medical Use of Cannabinoids--Reply

Whiting, P., 27 Oct 2015, In : JAMA - Journal of the American Medical Association. 314, 16, p. 1751-2 2 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)
7 Citations (Scopus)

Systematic review of intervention design and delivery in pragmatic and explanatory surgical randomized clinical trials

Blencowe, N. S., Boddy, A. P., Harris, A., Hanna, T., Whiting, P., Cook, J. A. & Blazeby, J. M., Aug 2015, In : British Journal of Surgery. 102, 9, p. 1037-47 11 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

The risks and benefits of patients temporarily discontinuing medications in the event of an intercurrent illness: a systematic review protocol

Morden, A. W., Horwood, J. P., Whiting, P. F., Savovic, J., Tomlinson, L., Blakeman, T., Tomson, C., Richards, A. C., Stone, T. J. & Caskey, F. J., 24 Oct 2015, In : Systematic Reviews. 4, 6 p., 139.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
411 Downloads (Pure)

Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness analysis

Whiting, P., Al, M., Westwood, M., Ramos, I. C., Ryder, S., Armstrong, N., Misso, K., Ross, J., Severens, J. & Kleijnen, J., Jul 2015, In : Health Technology Assessment. 19, 58, p. 1-228, v-vi

Research output: Contribution to journalArticle (Academic Journal)

120 Citations (Scopus)
2014

Epidermal growth factor receptor tyrosine kinase (EGFR-TK) mutation testing in adults with locally advanced or metastatic non-small cell lung cancer: a systematic review and cost-effectiveness analysis

Westwood, M., Joore, M., Whiting, P., van Asselt, T., Ramaekers, B., Armstrong, N., Misso, K., Severens, J. & Kleijnen, J., May 2014, In : Health Technology Assessment. 18, 32, p. 1-166 166 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Ivacaftor for the treatment of patients with cystic fibrosis and the G551D mutation: a systematic review and cost-effectiveness analysis

Whiting, P., Al, M., Burgers, L., Westwood, M., Ryder, S., Hoogendoorn, M., Armstrong, N., Allen, A., Severens, H. & Kleijnen, J., Mar 2014, In : Health Technology Assessment. 18, 18, p. 1-106 106 p.

Research output: Contribution to journalArticle (Academic Journal)

61 Citations (Scopus)

KRAS mutation testing of tumours in adults with metastatic colorectal cancer: a systematic review and cost-effectiveness analysis

Westwood, M., van Asselt, T., Ramaekers, B., Whiting, P., Joore, M., Armstrong, N., Noake, C., Ross, J., Severens, J. & Kleijnen, J., Oct 2014, In : Health Technology Assessment. 18, 62, p. 1-132 132 p.

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)

Meta-epidemiologic analysis indicates that MEDLINE searches are sufficient for diagnostic test accuracy systematic reviews

van Enst, W. A., Scholten, R. J. P. M., Whiting, P., Zwinderman, A. H. & Hooft, L., Nov 2014, In : Journal of Clinical Epidemiology. 67, 11, p. 1192-9 8 p.

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)

Protection by BCG vaccine against tuberculosis: A systematic review of randomized controlled trials

Mangtani, P., Abubakar, I., Ariti, C., Beynon, R., Pimpin, L., Fine, P. E. M., Rodrigues, L. C., Smith, P. G., Lipman, M., Whiting, P. F. & Sterne, J. A., 15 Feb 2014, In : Clinical Infectious Diseases. 58, 4, p. 470-480 11 p.

Research output: Contribution to journalArticle (Academic Journal)

317 Citations (Scopus)
2013

A systematic review classifies sources of bias and variation in diagnostic test accuracy studies

Whiting, P. F., Rutjes, A. W. S., Westwood, M. E., Mallett, S. & QUADAS-2 Steering Group, Oct 2013, In : Journal of Clinical Epidemiology. 66, 10, p. 1093-104 12 p.

Research output: Contribution to journalArticle (Academic Journal)

118 Citations (Scopus)

How to apply the results of a research paper on diagnosis to your patient

Whiting, P., Martin, R. M., Ben-Shlomo, Y., Gunnell, D. & Sterne, J. A. C., Jan 2013, In : JRSM Short Reports. 4, 1, p. 7

Research output: Contribution to journalArticle (Academic Journal)

Providing adequate and practical descriptions in surgical trials

Blencowe, N., Mills, N., Whiting, P. & Blazeby, J., 2013, In : BMJ. 347, p. f6143

Research output: Contribution to journalArticle (Academic Journal)