Personal profile
Research interests
My research focusses on how neuronal synchronization within the cortico-basal ganglia-thalamo-cortical network contributes to the coordination of neuronal activity for movement control and flexible behaviour. I am interested in understanding how mechanisms of neural communication are affected in Parkinson's disease, dystonia and in compulsive behavioural disorders. During my PhD, I recorded local field potentials from the subthalamic nucleus in patients undergoing deep brain stimulation surgery. Our studies have informed a new deep brain stimulation protocol, which is currently being tested in more detail to understand if it could help improve gait control.
I have collaborations with researchers in the US, UK and Germany on a range of projects including MEG recordings from patients, single cell recordings from rodents and non-human primate data.
Please see my lab website for more details.
Biography
In 2017, Petra received her D.Phil. in Clinical Neurosciences at the University of Oxford, where she was supervised by Professor Peter Brown and Huiling Tan. For Petra’s doctoral thesis, entitled "Neuronal dynamics of flexible motor control in the human subthalamic nucleus and cortex", she recorded local field potential activity from the subthalamic nucleus in people with Parkinson’s, studying the role of such activity in upper limb movements and gait.
Petra continued to work at the MRC Brain Network Dynamics Unit as a postdoctoral researcher, and in 2018, was appointed as Tilleard Cole Junior Research Fellow at Worcester College. In August 2021, Petra moved to the University of Bristol as a Lecturer in Neuroscience to set up her own research group.
Keywords
- Parkinson's disease
- movement disorders
- oscillations
- neural synchronization
- EEG
- deep brain stimulation
- basal ganglia
- compulsive behaviours
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Context-dependent modulations of subthalamo-cortical synchronization during rapid reversals of movement direction in Parkinson’s disease
Winkler, L., Butz, M., Sharma, A., Vesper, J., Schnitzler, A., Fischer, P. & Hirschmann, J., 5 Jun 2025, In: eLife. 13, 22 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Neurophysiological gradient in the Parkinsonian subthalamic nucleus as a marker for motor symptoms and apathy
Bernasconi, E., Amstutz, D., Averna, A., Fischer, P., Sousa, M., Debove, I., Petermann, K., Alva, L., Magalhães, A. D., Lachenmayer, M. L., Nguyen, T.-A. K., Schuepbach, M., Nowacki, A., Pollo, C., Krack, P. & Tinkhauser, G., 3 Jan 2025, In: npj Parkinson's Disease. 11, 1, 11 p., 4.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access4 Citations (Scopus) -
Spike-phase coupling of subthalamic neurons to posterior perisylvian cortex predicts speech sound accuracy
Vissani, M., Bush, A., Lipski, W. J., Bullock, L., Fischer, P., Neudorfer, C., Holt, L. L., Fiez, J. A., Turner, R. S. & Richardson, R. M., 9 Apr 2025, In: Nature Communications. 16, 1, 20 p., 3357.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access4 Citations (Scopus)
-
Personalised neurostimulation for Parkinson's inspired by neurophysiological improvements observed after physical exercise
Fischer, P. (Principal Investigator)
1/03/24 → 28/02/27
Project: Research
-
CloseNIT - Refining closed-loop vibrotactile stimulation tools to ameliorate dysfunctional network activity in dystonia
Fischer, P. (Principal Investigator)
1/04/23 → 31/03/24
Project: Research
Datasets
-
PD Warrior BRAIN task raw behavior task
Fischer, P. (Creator), Ni, R. (Creator) & Zorab, D. (Creator), University of Bristol, 3 Feb 2026
DOI: 10.5523/bris.1d20k1rpil31m2fekk7p1xfs4z, http://data.bris.ac.uk/data/dataset/1d20k1rpil31m2fekk7p1xfs4z
Dataset