Research output per year
Research output per year
Fingerprint
Dive into the research topics where Philip Hinchliffe is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
-
Interactions of hydrolyzed β-lactams with the L1 metallo-β-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products
Hinchliffe, P., Calvopiña, K., Rabe, P., Mojica, M. F., Schofield, C. J., Dmitrienko, G. I., Bonomo, R. A., Vila, A. J. & Spencer, J., 15 Mar 2023, (E-pub ahead of print) In: Journal of Biological Chemistry. 299, 5, 104606.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase
Tooke, C. L., Hinchliffe, P., Beer, M., Zinovjev, K., Colenso, C. K., Schofield, C. J., Mulholland, A. J. & Spencer, J., 5 Apr 2023, In: Journal of the American Chemical Society. 145, 13, p. 7166-7180 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)19 Downloads (Pure) -
A multiscale approach to predict the binding mode of metallo beta-lactamase inhibitors
Gervasoni, S., Spencer, J., Hinchliffe, P., Pedretti, A., Vairoletti, F., Mahler, G. & Mulholland, A. J., Feb 2022, In: Proteins: Structure, Function, and Bioinformatics. 90, 2, p. 372-384 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)42 Downloads (Pure)
Datasets
-
Crystallography and QM/MM Simulations Identify Preferential Binding of Hydrolyzed Carbapenem and Penem Antibiotics to the L1 Metallo-beta-lactamase in the Imine Form
Twidale, R. (Creator), Mulholland, A. J. (Creator), Hinchliffe, P. (Contributor) & Spencer, J. (Contributor), University of Bristol, 6 Oct 2021
DOI: 10.5523/bris.13pu85dfaobij2rumzql5buyy2, http://data.bris.ac.uk/data/dataset/13pu85dfaobij2rumzql5buyy2
Dataset