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Dr R R Foster

B.Sc.(Wales), Ph.D.(Bristol)

  • BS1 3NY

20032020

Research output per year

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Personal profile

Research interests

Becky Foster completed her BSc in Zoology at the University of Wales, Swansea in 1999. In 2001, she undertook a PhD in the Microvascular Research Laboratories, Department of Physiology, University of Bristol with Prof. Dave Bates and Dr Steve Harper, studying the role of vascular endothelial growth factor (VEGF)-A in podocyte biology, which she completed in 2004. Becky extended her interest in renal physiology as an MRC funded Post-doctoral research scientist in the Academic Renal Unit, School of Clinical Science @ North Bristol, University of Bristol with Prof Peter Mathieson and Prof Moin Saleem and later with Dr Simon Satchell. In 2010, she was awarded a BHF Intermediate Basic Science Research Fellowship to address the question "Can VEGF-C regulate VEGF-A induced changes in glomerular endothelial cell barrier properties in health and disease?" Since then she has been funded by the British Heart Foundation, Kidney Research UK, Diabetes Research and Wellness Foundation and European Foundation for the study of Diabetes. In 2015, she secured a lectureship at the University of Bristol and now splits her time between research and teaching.  She is particularly interested in the contribution of the endothelial cell glycocalyx (the protective layer that lines all blood vessels) to vessel barrier function within the kidney and beyond. She aims to identify therapeutic approaches that can restore the endothelial glycocalyx which will be common across vessel beds and vascular diseases.

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Projects

VEGFC gene manipulation to protect from diabetic nephropathy: a translational approach

Foster, R. R.

1/02/20 → 28/02/21

Project: Research

Copy of A New vascular therapeutic strategy for early intervention in diabetic vascular dysfunction

Foster, R. R.

1/09/16 → 23/02/21

Project: Research

8067 MRC CiC Commercial Development Fund from Andrew Wilson in RED. Initial in vitro PoC for gene therapy to treat diabetic nephropathy

Foster, R. R.

1/01/20 → 31/03/20

Project: Research

Research Output

  • 24 Article (Academic Journal)
  • 3 Review article (Academic Journal)
  • 2 Comment/debate (Academic Journal)

Response to There is little evidence that the endothelial glycocalyx has a specific role in glomerular permeability of albumin

Ramnath, R. D., Butler, M. N., Foster, R. R. & Satchell, S. C., 1 May 2020, In : Kidney International. 97, 5, p. 1057–1058 2 p.

Research output: Contribution to journal › Comment/debate (Academic Journal)

Open Access
File
    • 19 Downloads (Pure)

    The pathological relevance of increased endothelial glycocalyx permeability

    Butler, M., Down, C. J., Foster, R. R. & Satchell, S. C., 6 Feb 2020, In : American Journal of Pathology. 190, 4, p. 742-751 10 p.

    Research output: Contribution to journal › Review article (Academic Journal)

    • Aldosterone induces albuminuria via matrix metalloproteinase–dependent damage of the endothelial glycocalyx

    Butler, M. J., Ramnath, R., Kadoya, H., Desposito, D., Riquier-Brison, A., Ferguson, J. K., Onions, K. L., Ogier, A. S., ElHegni, H., Coward, R. J., Welsh, G. I., Foster, R. R., Peti-Peterdi, J. & Satchell, S. C., Jan 2019, In : Kidney International. 95, 1, p. 94-107 14 p.

    Research output: Contribution to journal › Article (Academic Journal)

    Open Access
    File
    • 9 Citations (Scopus)
    103 Downloads (Pure)

    Prizes

    MRC Confidence in concepts. VEGFC treatment to protect from diabetic nephropathy in type 1 diabetes: a translational approach

    Foster, R R (Recipient), 29 Feb 2012

    Prize: Prizes, Medals, Awards and Grants

    • MRC Confidence in concepts. VEGFC treatment to protect from diabetic nephropathy in type 1 diabetes: a translational approach

    Foster, R R (Recipient), 12 Feb 2020

    Prize: Other distinction

    • Activities

    • 2 Invited talk
    • 1 Editorial activity
    • 1 Fellowship awarded competitively
    • 1 Other

    VEGFC treatment to protect from diabetic nephropathy in type 1 diabetes: a translational approach

    R R Foster (Speaker)

    12 Feb 2020 → 11 Feb 2021

    Activity: Other activity types › Other

    11TH INTERNATIONAL PODOCYTE CONFERENCE

    R R Foster (Speaker)

    4 Apr 2016

    Activity: Participating in or organising an event types › Invited talk

    Scientific Reports (Journal)

    R R Foster (Editorial board member)

    1 Jul 2016 → 30 Jun 2018

    Activity: Publication peer-review and editorial work types › Editorial activity

    Supervised Work

    Aldosterone-induced endothelial glycocalyx dysfunction, a potential therapeutic target in proteinuria?

    Author: Butler, M., 25 Sep 2018

    Supervisor: Satchell, S. (Supervisor) & Foster, B. (Supervisor)

    Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

    File

    The effects of vascular endothelial growth factor on podocyte biology

    Author: Foster, R. R., 2004

    Supervisor: Harper, S. (Supervisor)

    Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

    File