Rach Hughes

2024

Analyses using multiple imputation need to consider missing data in auxiliary variables

Madley-Dowd, P., Curnow, E., Hughes, R. A., Cornish, R. P., Tilling, K. M. & Heron, J. E., 27 Aug 2024, (E-pub ahead of print) In: American Journal of Epidemiology. kwae306.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Multiple imputation strategies for missing event times in a multi-state model analysis

Curnow, E., Hughes, R., Birnie, K., Tilling, K. M. & Crowther, M. J., 22 Feb 2024, In: Statistics in Medicine. 43, 6, p. 1238-1255 18 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2023

Quantitative bias analysis in practice: Review of software for regression with unmeasured confounding

Kawabata, E., Tilling, K. M., Groenwold, R. & Hughes, R., 4 May 2023, In: BMC Medical Research Methodology. 23, 1, 111.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

Time-sensitive testing pressures and COVID-19 outcomes: are socioeconomic inequalities over the first year of the pandemic explained by selection bias?

Carter, A. R., Clayton, G. L., Borges, M. C., Howe, L. D., Hughes, R. A., Smith, G. D., Lawlor, D. A., Tilling, K. & Griffith, G. J., 26 Sept 2023, In: BMC Public Health. 23, 1, 1863.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2022

Developing decision support tools incorporating personalised predictions of likely visual benefit versus harm for cataract surgery: research programme

Sparrow, J. M., Grzeda, M. T., Frost, A., Liu, C., Johnston, R. L., Scanlon, P., Pithara-McKeown, C., Elliott, D., Donovan , J. L., Joseph-Williams, N., Holland-Hart, D., Donachie, P. H., Dixon, P. C., Kandiyali, R., Taylor, H., Breheny, K., Sterne, J. A. C., Hollingworth, W., Evans, D. & Fox, F. E. & 11 others, Theodoropoulou, S., Hughes, R., Quinn, M., Gray, D., Benjamin, L., Loose, A., Edwards, L., Craggs, P., Paget, F. V., Kapoor, K. & Searle, J., 1 Oct 2022, In: NIHR Open Research. 10, 9, 90 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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1 Citation (Scopus)

39 Downloads (Pure)

Exploring the impact of selection bias in observational studies of COVID-19: a simulation study

Millard, L. A. C., Fernandez Sanles, A., Carter, A. R., Hughes, R., Tilling, K. M., Morris, T. P., Smith, D., Griffith, G. J., Clayton, G. L., Kawabata, E., Davey Smith, G., Lawlor, D. A. & Borges, M. C., 6 Dec 2022, In: International Journal of Epidemiology.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Sample-constrained partial identification with application to selection bias

Tudball, M. J., Tilling, K. M. & Hughes, R., 25 Jul 2022, In: Biometrika. asac042.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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41 Downloads (Pure)

Using linear and natural cubic splines, SITAR, and latent trajectory models to characterise nonlinear longitudinal growth trajectories in cohort studies

Elhakeem, A., Hughes, R., Tilling, K. M., Cousminer, D. L., Jackowski, S., Cole, T. J., Kwong , A. S. F., Li, Z., Grant, S. F. A., Baxter-Jones, A., Zemel, B. S. & Lawlor, D. A., 15 Mar 2022, In: BMC Medical Research Methodology. 22, 1, 20 p., 68 .

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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15 Citations (Scopus)

212 Downloads (Pure)

2021

Combining longitudinal data from different cohorts to examine the life-course trajectory

Hughes, R. A., Tilling, K. & Lawlor, D. A., 2 Jul 2021, In: American Journal of Epidemiology. 190, 12, p. 2680-2689 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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12 Citations (Scopus)

90 Downloads (Pure)

Mendelian randomisation with coarsened exposures

Tudball, M. J., Bowden, J., Hughes, R., Ly, A., Munafo, M. R., Tilling, K. M., Zhao, Q. & Davey Smith, G., Apr 2021, In: Genetic Epidemiology. 45, 3, p. 338-350 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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14 Citations (Scopus)

101 Downloads (Pure)

Multiple imputation strategies for a bounded outcome variable in a competing risks analysis

Curnow, E., Hughes, R. A., Birnie, K., Crowther, M. J., May, M. T. & Tilling, K., 19 Oct 2021, (E-pub ahead of print) In: Statistics in Medicine. 40, 8, p. 1917-1929 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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3 Citations (Scopus)

168 Downloads (Pure)

Surgeon effects on cataract refractive outcomes are minimal compared with patient comorbidity and gender: an analysis of 490987 cases

Hughes, R., Aristodemou, P., Sparrow, J. M. & Kaye, S., 11 Nov 2021, (E-pub ahead of print) In: British Journal of Ophthalmology.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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7 Citations (Scopus)

20 Downloads (Pure)

2020

Bootstrap Inference for Multiple Imputation under Uncongeniality and Misspecification

Bartlett, J. W. & Hughes, R. A., 30 Jun 2020, (E-pub ahead of print) In: Statistical Methods in Medical Research. 29 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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50 Citations (Scopus)

291 Downloads (Pure)

Early life exposure to air pollution, green spaces and built environment, and body mass index growth trajectories during the first 5 years of life: a large longitudinal study

de Bont, J., Hughes, R., Tilling, K. M., Diaz, Y., de Castro, M., Cirach, M., Fossati, S., Nieuwenhuijsen, M., Duarte-Salles, T. & Vrijheid, M., 1 Nov 2020, In: Environmental Pollution. 266, 3, 11 p., 115266.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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32 Citations (Scopus)

319 Downloads (Pure)

2019

Accounting for missing data in statistical analyses: multiple imputation is not always the answer

Hughes, R. A., Heron, J., Sterne, J. A. C. & Tilling, K., 1 Aug 2019, In: International Journal of Epidemiology. 48, 4, p. 1294-1304 11 p., dyz032.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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403 Citations (Scopus)

631 Downloads (Pure)

Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability

Eyre, O., Hughes, R. A., Thapar, A. K., Leibenluft, E., Stringaris, A., Davey Smith, G., Stergiakouli, E., Collishaw, S. & Thapar, A., 1 Aug 2019, In: Journal of Child Psychology and Psychiatry. 60, 8, p. 866-874 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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34 Citations (Scopus)

521 Downloads (Pure)

Domestic violence is a health problem in the Arab world: a systematic review and meta-analysis

Hawcroft, C. S., Hughes, R., Shaheen, A., Usta, J., Elkadi, H., Dalton, T., Ginwalla, K. & Feder, G. S., 2019.

Research output: Contribution to conference › Conference Paper

Prevalence and health outcomes of domestic violence amongst clinical populations in Arab countries: a systematic review and meta-analysis

Hawcroft, C., Hughes, R., Shaheen, A., Usta, J., Elkadi, H., Dalton, T., Ginwalla, K. & Feder, G., 18 Mar 2019, In: BMC Public Health. 19, 1, 12 p., 315.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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60 Citations (Scopus)

460 Downloads (Pure)

Selection bias when estimating average treatment effects using one-sample instrumental variable analysis

Hughes, R. A., Davies, N. M., Davey Smith, G. & Tilling, K., 1 May 2019, In: Epidemiology. 30, 3, p. 350-357 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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51 Citations (Scopus)

368 Downloads (Pure)

The proportion of missing data should not be used to guide decisions on multiple imputation

Madley-Dowd, P., Hughes, R., Tilling, K. & Heron, J., 13 Jun 2019, In: Journal of Clinical Epidemiology. 110, p. 63-73 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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594 Citations (Scopus)

1562 Downloads (Pure)

2018

Interventions to support shared decision making for hypertension: A systematic review of controlled studies

Johnson, R., Huntley, A., Hughes, R., Cramer, H., Turner, K., Perkins, B. & Feder, G., 1 Dec 2018, In: Health Expectations. 21, 6, p. 1191-1207 17 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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30 Citations (Scopus)

980 Downloads (Pure)

Long terms trends in CD4⁺ cell counts, CD8⁺ cell counts, and the CD4⁺:CD8⁺ ratioCD8⁺ ratio

Hughes, R. A., May, M. T., Tilling, K., Taylor, N., Wittkop, L., Reiss, P., Gill, J., Schommers, P., Costagliola, D., Guest, J. L., Lima, V. D., D'Arminio Monforte, A., Smith, C., Cavassini, M., Saag, M., Castilho, J. L. & Sterne, J. A. C., 19 Jun 2018, In: AIDS. 32, 10, p. 1361-1367 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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21 Citations (Scopus)

186 Downloads (Pure)

Relative efficiency of joint-model and full-conditional-specification multiple imputation when conditional models are compatible: The general location model

Seaman, S. R. & Hughes, R. A., Jun 2018, In: Statistical Methods in Medical Research. 27, 6, p. 1603-1614 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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17 Citations (Scopus)

350 Downloads (Pure)

Socioeconomic differences in childhood BMI trajectories in Belarus

Patel, R., Tilling, K., Lawlor, D., Howe, L., Hughes, R., Bogdanovich, N., Matush, L., Nicoli, E. J., Oken, E., Kramer, M. S. & Martin, R., 28 Feb 2018, (E-pub ahead of print) In: International Journal of Obesity. 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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9 Citations (Scopus)

307 Downloads (Pure)

2017

Analysing repeated measurements whilst accounting for derivative tracking, varying within-subject variance, and autocorrelation: the xtmixediou command

Hughes, R., Kenward, M., Sterne, J. & Tilling, K., 1 Sept 2017, In: Stata Journal. 17, 3, p. 573-599 27 p., st0487.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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167 Downloads (Pure)

Estimation of the linear mixed integrated Ornstein-Uhlenbeck model

Hughes, R., Kenward, M., Sterne, J. A. C. & Tilling, K., May 2017, In: Journal of Statistical Computation and Simulation. 87, 8, p. 1541-1558 18 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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6 Citations (Scopus)

364 Downloads (Pure)

2016

Comparison of imputation variance estimators

Hughes, R. A., Sterne, J. A. C. & Tilling, K., 1 Dec 2016, In: Statistical Methods in Medical Research. 25, 6, p. 2541-2557 17 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

31 Citations (Scopus)

Predicting virological decay in patients starting combination antiretroviral therapy

The UK Collaborative HIV Cohort (UK CHIC) Writing Committee, 17 Jul 2016, In: AIDS. 30, 11, p. 1817-1821 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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4 Citations (Scopus)

327 Downloads (Pure)

2015

Childhood wheezing, asthma, allergy, atopy, and lung function: different socioeconomic patterns for different phenotypes

Galobardes, B., Granell, R., Sterne, J., Hughes, R., Mejia-Lancheros, C., Davey Smith, G. & Henderson, J., 1 Nov 2015, In: American Journal of Epidemiology. 182, 9, p. 763-774 12 p., kwv045.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

47 Citations (Scopus)

Maternal and childhood psychological factors predict chronic disabling fatigue at age 13 years

Collin, S. M., Tilling, K., Joinson, C., Rimes, K. A., Pearson, R. M., Hughes, R. A., Sterne, J. A. C. & Crawley, E., 1 Feb 2015, In: Journal of Adolescent Health. 56, 2, p. 181-187 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

22 Citations (Scopus)

2014

Joint modelling rationale for chained equations

Hughes, R. A., White, I. R., Seaman, S. R., Carpenter, J. R., Tilling, K. & Sterne, J. A. C., 21 Feb 2014, In: BMC Medical Research Methodology. 14, p. 28 10 p., 28.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

66 Citations (Scopus)

Modelling childhood growth using fractional polynomials and linear splines

Tilling, K., Macdonald-Wallis, C., Lawlor, D. A., Hughes, R. A. & Howe, L. D., 2014, In: Annals of Nutrition and Metabolism. 65, 2-3, p. 129-38 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

75 Citations (Scopus)

2012

Adolescent perspectives on wearing accelerometers to measure physical activity in population-based trials

Audrey, S., Bell, S. L., Hughes, R. A. & Campbell, R. M., 2012, In: European Journal of Public Health.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

47 Citations (Scopus)

Reducing smoking in adolescents: cost-effectiveness results from the cluster randomised ASSIST (a stop smoking in schools trial)

Hollingworth, W., Cohen, D., Hawkins, J., Hughes, R., Moore, L., Holliday, J., Audrey, S., Starkey, F. & Campbell, R., 2012, In: Nicotine and Tobacco Research. 14, 2, p. 161-168

Research output: Contribution to journal › Article (Academic Journal) › peer-review

32 Citations (Scopus)

2011

Associations of gestational weight gain with maternal body mass index, waist circumference, and blood pressure measured 16 y after pregnancy: the Avon Longitudinal Study of Parents and Children

Fraser, A., Tilling, K., Macdonald-Wallis, C., Hughes, R., Sattar, N., Nelson, S. M. & Lawlor, D. A., Jun 2011, In: American Journal of Clinical Nutrition. 93, 6, p. 1285-1292 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

170 Citations (Scopus)

Associations of Gestational Weight Gain With Maternal Body Mass Index, Waist Circumference, and Blood Pressure Measured 16 Years After Pregnancy: The Avon Longitudinal Study of Parents and Children

Fraser, A., Tilling, K., MacDonald-Wallis, C., Hughes, R., Sattar, N., Nelson, S. M. & Lawlor, D. A., Oct 2011, In: Obstetrical and Gynecological Survey. 66, 10, p. 599-600 2 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

13 Citations (Scopus)

Long-term trends in CD4 cell counts and impact of viral failure in individuals starting antiretroviral therapy: UK Collaborative HIV Cohort (CHIC) study

Hughes, R. A., Sterne, J. A. C., Walsh, J., Bansi, L., Gilson, R., Orkin, C., Hill, T., Ainsworth, J., Anderson, J., Gompels, M., Dunn, D., Johnson, M. A., Phillips, A. N., Pillay, D., Leen, C., Easterbrook, P., Gazzard, B., Fisher, M. & Sabin, C. A., Nov 2011, In: HIV Medicine. 12, 10, p. 583-93 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

27 Citations (Scopus)

Social adversity at birth predicts disabling fatigue at 13 years: population-based study

Crawley, E., Hughes, R., Northstone, K., Tilling, K., Emond, A. & Sterne, J., 2011, In: Pediatrics. 130, p. e71-e79

Research output: Contribution to journal › Article (Academic Journal) › peer-review

2010

Health-related quality of life after minimally invasive oesophagectomy

Parameswaran, R., Blazeby, J., Hughes, R., Mitchell, K., Berrisford, R. & Wajed, S., Apr 2010, In: British Journal of Surgery. 97, 4, p. 525 - 531 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

79 Citations (Scopus)

Health-related quality of life and survival in the 2 years after surgery for gastric cancer

Avery, K., Hughes, R., Mcnair, A. G. K., Alderson, D., Barham, P. & Blazeby, J., Feb 2010, In: European Journal of Surgical Oncology. 36(2), p. 148 - 154 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

61 Citations (Scopus)

2009

Determinants of global quality of life before and after major cancer surgery: an exploratory study

Rutegard, M., Hughes, R., Lagergren, P. & Blazeby, J., Nov 2009, In: Quality of Life Research. 18(9), p. 1131 - 1136 6 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

7 Citations (Scopus)

2008

An informal school-based peer-led intervention for smoking prevention in adolescence (ASSIST): a cluster randomised trial

Campbell, R., Starkey, F., Holliday, J., Audrey, S., Bloor, M., Parry-Langdon, N., Hughes, R. & Moore, L., 10 May 2008, In: Lancet. 371, 9624, p. 1595 - 1602 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

329 Citations (Scopus)

Early life growth and hemostatic factors: The Barry Caerphilly Growth Study

Fraser, A., Hughes, R., McCarthy, A., Tilling, K., Davies, D., Rumley, A., Lowe, G., Davey Smith, G. & Ben-Shlomo, Y., 15 Jul 2008, In: American Journal of Epidemiology. 168, 2, p. 179 - 187 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

11 Citations (Scopus)

Immediate post-natal growth is associated with blood pressure in young adulthood: the Barry Caerphilly Growth Study

Ben-Shlomo, Y., McCarthy, [. V., Hughes, R., Tilling, K., Davies, D. & Davey Smith, G., Oct 2008, In: Hypertension. 52, 4, p. 638 - 644 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

94 Citations (Scopus)

Long-term immunologic response to antiretroviral therapy in low income countries: a collaborative analysis of prospective studies

Nash, D., May, M., Sterne, J., Dabis, F., Egger, M., Sprinz, E., Brinkhof, M., Katyal, M., Wood, R., Hughes, R. & Kaiser, O., Nov 2008, In: AIDS. 22, p. 2291 - 2302 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

156 Citations (Scopus)

2007

Birth weight, post-natal, infant and childhood growth and obesity in young adulthood: Evidence from the Barry Caerphilly Growth (BCG) Study

McCarthy, A., Hughes, R., Tilling, K., Davies, D., Davey Smith, G. & Ben-Shlomo, Y., 2007, In: American Journal of Clinical Nutrition. 86, p. 907 - 913

Research output: Contribution to journal › Article (Academic Journal) › peer-review

121 Citations (Scopus)

Health-related quality of life among patients cured by surgery for esophageal cancer

Lagergren, P., Avery, K., Hughes, R., Barham, C., Alderson, D., Falk, S. & Blazeby, J., Aug 2007, In: Cancer. 110(3), p. 686 - 693 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

173 Citations (Scopus)

Dr Rach Hughes

Research output

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