Rachel E Denholm

2025

Impact of COVID-19 pandemic on rates of congenital heart disease procedures among children: Prospective cohort analyses of 26,270 procedures in 17,860 children using CVD-COVID-UK consortium record linkage data

Karthikeyan Suseeladevi, A., Denholm, R. E., Babu-Narayan, S., Sinha, S., Stoica, S. C., Dong, T., Angelini, G. D., Sudlow, C., Walker, V. M., Brown, K., Caputo, M., Lawlor, D. A. & CVD-COVID-UK/COVID-IMPACT Consortium , 10 Mar 2025, (Accepted/In press) In: Open Heart.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Risks of major arterial and venous thrombotic diseases after hospitalisation for influenza, pneumonia, and COVID-19: A population-wide cohort in 2.6 million people in Wales

CVD-COVID-UK/COVID-IMPACT Consortium and the Longitudinal Health and Wellbeing COVID-19 National Core Study, Keene, S., Abbasizanjani, H., Torabi, F., Knight, R., Walker, V., Raffetti, E., Cezard, G., Ip, S., Sampri, A., Bolton, T., Denholm, R., Khunti, K., Akbari, A., Quint, J., Denaxas, S., Sudlow, C., Di Angelantonio, E., Sterne, J. A. C. & Wood, A. & 1 others, Whiteley, W. N., 1 Jan 2025, In: Thrombosis Research. 245, p. 109213 109213.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2024

Acute and long-term outcomes of SARS-CoV-2 infection in school-aged children in England: Study protocol for the joint analysis of the COVID-19 Schools Infection Survey (SIS) and the COVID-19 Mapping and Mitigation in Schools (CoMMinS) Study

Looker, K. J., McClenaghan, E., Judd, A., Pierotti, L., Downing, H. E., Phelan, J., Warren-Gash, C., Kalu, N., Dawe, F., Relton, C. L., Christensen, H., Hay, A. D., Mangtani, P., Nguipdop Djomo, P. & Denholm, R. E., 22 May 2024, In: PLoS ONE. 19, 5, e0303892.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Can computer simulation support strategic service planning? Modelling a large integrated mental health system on recovery from COVID-19

Pierotti, L., Cooper, J., James, C., Cassels, K., Gara, E., Denholm, R. & Wood, R., 1 Dec 2024, In: International journal of mental health systems. 18, 1, 12 p., 12.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Cohort study of cardiovascular safety of different COVID-19 vaccination doses among 46 million adults in England

Ip, S., North, T.-L., Torabi, F., Li, Y., Abbasizanjani, H., Akbari, A., Horne, E. M. F., Denholm, R. E., Keene, S., Denaxas, S., Banerjee, A., Khunti, K., Sudlow, C., Whiteley, W. N., Sterne, J. A. C., Wood, A. M., Walker, V. M., CVD-COVID-UK/COVID-IMPACT Consortium & Longitudinal Health and Wellbeing COVID-19 National Core Study, 31 Jul 2024, In: Nature. 15, 1, 12 p., 6085.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

8 Citations (Scopus)

COVID-19 and Mental Illnesses in Vaccinated and Unvaccinated People

Walker, V. M., Patalay, P., Cuitun Coronado, J. I., Denholm, R. E., Forbes, H., Stafford, J., Moltrecht, B., Palmer, T. M., Walker, A., Thompson, E. J., Taylor, K. R., Cezard, G., Horne, E. M. F., Wei, Y., AL Arab, M. M., Knight, R. O. C., Fisher, L., Massey, J., Davy, S. & Mehrkar, A. & 7 others, Bacon, S., Goldacre , B., Wood, A., Chaturvedi, N., Macleod, J. A. A., John, A. & Sterne, J. A. C., 1 Nov 2024, In: JAMA Psychiatry. 81, 11, p. 1071-1080 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

5 Citations (Scopus)

COVID-19 diagnosis, vaccination during pregnancy, and adverse pregnancy outcomes of 865,654 women in England and Wales: a population-based cohort study

CVD-COVID-UK/COVID-IMPACT Consortium , Longitudinal Health and Wellbeing COVID-19 National Core Study, Raffetti, E., Bolton, T., Nolan, J., Zuccolo, L., Denholm, R., Smith, G., Akbari, A., Harron, K., Curry, G., Allara, E., Lawlor, D. A., Caputo, M., Abbasizanjani, H., Chico, T. & Wood, A. M., 1 Oct 2024, In: The Lancet Regional Health - Europe. 45, 12 p., 101037.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

COVID-19 vaccination and birth outcomes of 186,990 women vaccinated before pregnancy: an England-wide cohort study

Suseeladevi, A. K., Denholm, R., Retford, M., Raffetti, E., Burden, C., Birchenall, K., Male, V., Walker, V., Tomlinson, C., Wood, A. M., Zuccolo, L. & CVD-COVID-UK/COVID-IMPACT Consortium , 1 Oct 2024, In: The Lancet Regional Health - Europe. 45, 12 p., 101025.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

1 Citation (Scopus)

Effectiveness of mRNA COVID-19 vaccines as first booster doses in England: an observational study in OpenSAFELY-TPP

OpenSAFELY Collaborative, 24 Jun 2024, (E-pub ahead of print) In: Epidemiology. 35, 4, p. 568-578 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Explainable AI for Classifying UTI Risk Groups Using a Real-World Linked EHR and Pathology Lab Dataset

Dai, Y., Sullivan, B., Montout, A., Dillon, A., Waller, C., Acs, P., Denholm, R., Williams, P., Hay, A. D., Santos-Rodriguez, R. & Dowsey, A., 26 Nov 2024, arXiv.org.

Research output: Working paper › Preprint

Impact of vaccination on the association of COVID-19 with cardiovascular diseases: an OpenSAFELY cohort study

Cezard, G. I., Denholm, R. E., Knight, R. O. C., Wei, Y., Teece, L., Toms, R. M. B. S., Forbes, H. J., Walker, A. J., Fisher, L., Massey, J., Hopcroft, L. E., Horne, E. M. F., Taylor, K. R., Palmer, T. M., AL Arab, M. M., Ignacio Cuitun Coronado, J., Ip, S., Davy, S., Dillingham, I. & Bacon, S. & 12 others, Mehrkar, A., Morton, C. E., Greaves, F., Hyams, C., Davey Smith, G., MacLeod, J., Chaturvedi, N., Goldacre , B., Whiteley, W., Wood, A. M., Sterne, J. A. C. & Walker, V. M., 11 Mar 2024, In: Nature Communications. 15, 1, 14 p., 2173 .

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

11 Citations (Scopus)

Incidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people

Longitudinal Health and Wellbeing and Data and Connectivity UK COVID-19 National Core Studies, 1 Aug 2024, In: Lancet Diabetes and Endocrinology. 12, 8, p. 558-568 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

4 Citations (Scopus)

The cost of keeping patients waiting: Retrospective treatment-control study of additional healthcare utilisation for UK patients awaiting elective treatment

James, C. R., Denholm, R. E. & Wood, R., 30 Apr 2024, In: BMC Health Services Research. 24, 1, p. 1-10 10 p., 556.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

3 Citations (Scopus)

The effectiveness of knowledge-sharing techniques and approaches in research funded by the National Institute for Health and Care Research (NIHR): a systematic review

Baxter, H., Bearne, L., Stone, T., Thomas, C., Denholm, R., Redwood, S., Purdy, S. & Huntley, A. L., 2 Apr 2024, In: Health Research Policy and Systems. 22, 41.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2023

A multi-granular stacked regression for forecasting long-term demand in Emergency Departments

James, C. R., Wood, R. & Denholm, R. E., 7 Feb 2023, In: BMC Medical Informatics and Decision Making. 23, 1, 11 p., 29.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

UK research data resources based on primary care electronic health records: review and summary for potential users

Denholm, R. E., 19 Sept 2023, In: BJGP Open. 7, 3, 10 p., BJGPO.2023.0057.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

2022

Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England

CVD-COVID-UK consortium & Whiteley, W. N., 22 Feb 2022, In: PLoS Medicine. 19, 2, 20 p., e1003926.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

61 Citations (Scopus)

79 Downloads (Pure)

Association of COVID-19 with major arterial and venous thrombotic diseases: a population-wide cohort study of 48 million adults in England and Wales

Knight, R. O. C., Walker, V. M., Ip, S., Cooper, J. A., Bolton, T., Keene, S., Denholm, R. E., Akbari, A., Abbasizanjani, H., Torabi, F., Omigie, E., Hollings, S., North, T.-L., Toms, R. M. B. S., Jiang, X., Di Angelantonio, E., Denaxas, S., Thygesen, J. H., Tomlinson, C. & Bray, B. & 9 others, Smith, C. J., Barber, M., Khunti, K., Davey Smith, G., Chaturvedi, N., Sudlow, C., Whiteley, W., Wood, A. M. & Sterne, J. A. C., 20 Sept 2022, In: Circulation. 42 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

168 Citations (Scopus)

2021

A multi-stakeholder approach to the coproduction of the research agenda for medicines optimisation

Fellenor, J., Britten, N., Courtenay, M., Payne, R. A., Valderas, J., Denholm, R. E., Duncan, P. R., Mccahon, D., Tatnell, L., Fitzgerald, R., Warmoth, K., Gillespie, D., Turner, K. M. & Watson, M., 13 Jan 2021, In: BMC Health Services Research. 64.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

7 Citations (Scopus)

130 Downloads (Pure)

Cancer incidence in agricultural workers: Findings from an international consortium of agricultural cohort studies (AGRICOH)

Togawa, K., Leon, I., Lebailly, P., Beane Freeman, L. E., Denholm, R. E. & Schuz, J., 27 Aug 2021, In: Environment International. 157, 106825.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

40 Citations (Scopus)

55 Downloads (Pure)

Changes in presentations with features potentially indicating cancer in primary care during the COVID-19 pandemic: a retrospective cohort study

Scott, L. J., Murphy, C., Price, S., Horwood, J. P., Denholm, R. E., Lewis, R., Palmer, T. M. & Salisbury, C., 24 May 2021, In: BMJ Open. 11, 5, 11 p., e050131.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

9 Citations (Scopus)

89 Downloads (Pure)

Development of a model of medication review for use in clinical practice: Bristol Medication Review Model

McCahon, D., Denholm, R. E., Huntley, A. L., Dawson, S., Duncan, P. R. & Payne, R. A., 10 Nov 2021, In: BMC Medicine. 19, 1, 10 p., 262.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

12 Citations (Scopus)

175 Downloads (Pure)

Implementation of remote consulting in UK primary care following the COVID-19 pandemic: a mixed-methods longitudinal study

Murphy, M., Scott, L. J., Salisbury, C., Turner, A., Scott, A., Denholm, R., Iyer, G., Lewis, R., MacLeod, J. & Horwood, J., Mar 2021, In: British Journal of General Practice. 71, 704, p. E166-E177 12 p., e166-e177.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

299 Citations (Scopus)

316 Downloads (Pure)

Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource

CVD-COVID-UK consortium, Wood, A., Denholm, R., Hollings, S., Cooper, J., Ip, S., Walker, V., Denaxas, S., Akbari, A., Banerjee, A., Whiteley, W., Lai, A., Sterne, J. & Sudlow, C., 7 Apr 2021, In: BMJ (Clinical Research ed.). 373, p. n826 n826.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

100 Citations (Scopus)

91 Downloads (Pure)

Maintaining face-to-face contact during the COVID-19 pandemic: a longitudinal qualitative investigation in UK primary care

Turner, A., Scott, A., Horwood, J., Salisbury, C., Denholm, R., Scott, L., Iyer, G., Macleod, J. & Murphy, M., Oct 2021, In: British Journal of General Practice Open. 5, 5, p. 1-11 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

19 Citations (Scopus)

102 Downloads (Pure)

Primary Care implementation of Germ Defence, a digital behaviour change intervention to improve household infection control during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial

Horwood, J., Chalder, M., Ainsworth, B., Denison-Day, J., de Vocht, F., Elwenspoek, M. M. C., Craggs, P., Denholm, R., Sterne, J., Rice, C., Miller, S., Stuart, B., Little, P., Moore, M., Willcox, M., Macleod, J., Gullford, M., Morton, K., Towler, L. & Francis, N. & 2 others, Amlôt, R. & Yardley, L., 9 Apr 2021, In: Trials. 22, 1, 3 p., 263.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

6 Citations (Scopus)

66 Downloads (Pure)

2020

Impact of emergency hospital admissions upon patterns of primary care prescribing: a retrospective cohort analysis of electronic records

Denholm, R. E., Morris, R. W., Purdy, S. & Payne, R. A., 1 Jun 2020, In: British Journal of General Practice Open. 70, 695, p. e399-e405 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

70 Downloads (Pure)

International prescribing patterns and polypharmacy in older people with advanced chronic kidney disease: results from the European Quality Study

Hayward, S., Hole, B., Denholm, R., Duncan, P., Caskey, F. J. & al., E., 16 Jun 2020, In: Nephrology Dialysis Transplantation. 9 p., gfaa064.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

33 Citations (Scopus)

64 Downloads (Pure)

Uptake of direct oral anticoagulants in primary care: an ecological and economic study

Denholm, R., Thom, H. H. Z., Hollingworth, W. & Payne, R., 23 Jun 2020, In: British Journal of General Practice Open.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

2 Citations (Scopus)

Use of antibiotics and asthma medication for acute lower respiratory tract infections in people with and without asthma: retrospective cohort study

Denholm, R., Van der Werf, E. T. & Hay, A. D., 6 Jan 2020, In: Respiratory Research. 21, 12 p., 4 (2020).

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

14 Citations (Scopus)

213 Downloads (Pure)

2019

Completeness and validity of alcohol recording in general practice within the UK: a cross-sectional study

Mansfield, K., Crellin, E., Denholm, R., Quint, J. K., Smeeth, L., Cook, S. & Herrett, E., 26 Nov 2019, In: BMJ Open. 9, 11, 11 p., e031537.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

21 Citations (Scopus)

120 Downloads (Pure)

Ethnic and age differences in right-left breast asymmetry in a large population-based screening population

Hudson, S. M., Wilkinson, L. S., Denholm, R., De Stavola, B. L. & dos Santos Silva, I., 4 Nov 2019, In: British Journal of Radiology. 93, 1105, 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

8 Citations (Scopus)

48 Downloads (Pure)

Polypharmacy patterns in the last year of life in patients with dementia

Denholm, R., Morris, R. & Payne, R., 25 Jul 2019, (E-pub ahead of print) In: European Journal of Clinical Pharmacology. 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

16 Citations (Scopus)

229 Downloads (Pure)

2018

Circulating growth and sex hormone levels and breast tissue composition in young nulliparous women

Denholm, R., De Stavola, B. L., Hipwell, J. H., Doran, S. J., Holly, J. M. P., Folkerd, E., Dowsett, M., Leach, M. O., Hawkes, D. J. & Dos-Santos-Silva, I., 1 Dec 2018, In: Cancer Epidemiology, Biomarkers and Prevention. 27, 12, p. 1500-1508 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

4 Citations (Scopus)

125 Downloads (Pure)

Growth Trajectories, Breast Size, and Breast-Tissue Composition in a British Pre-Birth Cohort of Young Women

Denholm, R., De Stavola, B., Hipwell, J. H., Doran, S. J., Busana, M. C., Leach, M. O., Hawkes, D. J. & Dos-Santos-Silva, I., Jun 2018, In: American Journal of Epidemiology. 187, 6, p. 1259-1268 10 p., kwx358.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

9 Citations (Scopus)

322 Downloads (Pure)

THREE AUTHORS REPLY

Denholm, R., 23 May 2018, In: American Journal of Epidemiology.

Research output: Contribution to journal › Letter (Academic Journal)

1 Citation (Scopus)

2017

Breast MRI segmentation for density estimation: Do different methods give the same results and how much do differences matter?

Doran, S. J., Hipwell, J. H., Denholm, R., Eiben, B., Busana, M., Hawkes, D. J., Leach, M. O. & Dos Santos Silva, I., 1 Sept 2017, In: Medical Physics. 44, 9, p. 4573-4592 20 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

24 Citations (Scopus)

267 Downloads (Pure)

2016

Environmental carcinogen exposure and lifestyle factors affecting cancer risk in Qatar: findings from a qualitative review

Denholm, R., Schüz, J., Straif, K., Ali, F. M. H., Bonas, F., Gjebrea, O., Sifton, C. & Olsson, A. C., 15 Jun 2016, In: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit. 22, 3, p. 219-27 9 p.

Research output: Contribution to journal › Review article (Academic Journal) › peer-review

Open Access

File

6 Citations (Scopus)

266 Downloads (Pure)

Height and Risk of Adult Cancers: a Review

dos Santos Silva, I. & Denholm, R., 15 Jul 2016, In: Current Epidemiology Reports. 3, 3, p. 191-200 9 p.

Research output: Contribution to journal › Review article (Academic Journal) › peer-review

Open Access

3 Downloads (Pure)

Impact of type of full-field digital image on mammographic density assessment and breast cancer risk estimation: a case-control study

Busana, M. C., Eng, A., Denholm, R., Dowsett, M., Vinnicombe, S., Allen, S. & Dos-Santos-Silva, I., 26 Sept 2016, In: Breast Cancer Research. 18, 12 p., 96.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

15 Citations (Scopus)

281 Downloads (Pure)

Pre-natal exposures and breast tissue composition: Findings from a British pre-birth cohort of young women and a systematic review

Denholm, R., De Stavola, B., Hipwell, J. H., Doran, S. J., Busana, M. C., Eng, A., Jeffreys, M., Leach, M. O., Hawkes, D. & dos Santos Silva, I., 12 Oct 2016, In: Breast Cancer Research. 18, 14 p., 102.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

17 Citations (Scopus)

266 Downloads (Pure)

2014

Child maltreatment and household dysfunction: Associations with pubertal development in a British birth cohort

Li, L., Denholm, R. & Power, C., 1 Jan 2014, In: International Journal of Epidemiology. 43, 4, p. 1163-1173 11 p., dyu071.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

41 Citations (Scopus)

Is previous respiratory disease a risk factor for lung cancer?

Denholm, R., Schüz, J., Straif, K., Stücker, I., Jöckel, K. H., Brenner, D. R., De Matteis, S., Boffetta, P., Guida, F., Brüske, I., Wichmann, H. E., Landi, M. T., Caporaso, N., Siemiatycki, J., Ahrens, W., Pohlabeln, H., Zaridze, D., Field, J. K., McLaughlin, J. & Demers, P. & 15 others, Szeszenia-Dabrowska, N., Lissowska, J., Rudnai, P., Fabianova, E., Dumitru, R. S., Bencko, V., Foretova, L., Janout, V., Kendzia, B., Peters, S., Behrens, T., Vermeulen, R., Brüning, T., Kromhout, H. & Olsson, A. C., 1 Sept 2014, In: American Journal of Respiratory and Critical Care Medicine. 190, 5, p. 549-559 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

99 Citations (Scopus)

2013

Adverse childhood experiences and child-to-adult height trajectories in the 1958 British birth cohort

Denholm, R., Power, C. & Li, L., 1 Oct 2013, In: International Journal of Epidemiology. 42, 5, p. 1399-1409 11 p., dyt169.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

28 Citations (Scopus)

Child maltreatment and household dysfunction in a British Birth Cohort

Denholm, R., Power, C., Li, L. & Thomas, C., 1 Sept 2013, In: Child Abuse Review. 22, 5, p. 340-353 14 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

34 Citations (Scopus)

2010

Distribution and characteristics of sexual health service provision in primary and community care in England

Yung, M., Denholm, R., Peake, J. & Hughes, G., Sept 2010, In: International Journal of STD and AIDS. 21, 9, p. 650-2 3 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

10 Citations (Scopus)

Dr Rachel E Denholm

Research output

Search results