Professor Raimondo Ascione

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• Active

  Regulatory bench-testing of a transformational polymeric heart valve: a key step toward a first-in-human trial to benefit patients aged 18-80 plus with one valve type.

  Ascione, R. (Principal Investigator) & Mumford, A. D. (Co-Investigator)

  1/06/22 → 31/05/25

  Project: Research

• SOCS BHF RM/17/3/33381 OAFI

  Ascione, R. (Principal Investigator)

  8/03/18 → …

  Project: Research

• Pericardial adipose tissue stem cells extraction and expansion for cardiovascular regenerative medicine applications.

  Ascione, R. (Principal Investigator) & Norris, C. E. (Student)

  8/07/13 → …

  Project: Research

  • Cardiovascular System 100%
  • Cardiovascular Disease 100%
  • Biomedical Research 100%
  • Adipose Tissue 100%
  • Doctor of Philosophy 100%
• Not started

  59516: Collaboration Agreement: Special Project Grant: A Polymeric Prosthetic Heart Valve from anisotropic nanocomposites device optimisation and in vivo testing

  Ascione, R. (Principal Investigator)

  Project: Research

• Finished

  Immunoengineering Body Fat: Modelling microphages in a 3D-bioprinted human adipose tissue model

  Ascione, R. (Principal Investigator)

  1/01/23 → 30/06/24

  Project: Research

• PoliValve: Improving patients’ quality of life and reducing healthcare costs throughnext generation heart valves

  Ascione, R. (Principal Investigator)

  1/10/21 → 30/09/22

  Project: Research

• 8065 COVID-19 CoA (Extension to R100684-101) Innovate UK: (Arterius) Preclinical Development and Testing of Innovative Bioresorbable Stents to Treat Patients with Severe Peripheral Arterial Disease

  Ascione, R. (Principal Investigator)

  1/06/21 → 30/09/21

  Project: Research

• BHF via Oxford: Coronary microvascular actions of neuropeptide Y

  Ascione, R. (Principal Investigator)

  22/03/21 → 21/03/24

  Project: Research

• Preclinical Development and Testing of Innovative Bioresorbable Stents to Treat Patients with Severe Peripheral Arterial Disease.

  Ascione, R. (Principal Investigator) & George, S. J. (Co-Investigator)

  4/03/19 → 28/02/21

  Project: Research

  • Limb Amputation 100%
  • Vascular Stent 100%
  • Apoplexy 100%
  • Arteriosclerosis Obliterans 100%

• 8065 Innovate UK: (Arterius) Preclinical Development and Testing of Innovative Bioresorbable Stents to Treat Patients with Severe Peripheral Arterial Disease

  Ascione, R. (Principal Investigator)

  1/03/19 → 30/11/21

  Project: Research

• 8065 BHF via Edinburgh: BHF Centre for Cardiovascular Regenerative Medicine Award (II) RM/17/3/33381

  Ascione, R. (Principal Investigator)

  1/01/19 → 30/06/22

  Project: Research, Parent

• Rework of Consecutive isoprenaline/adenosine as a novel treatment to improve myocardial protection in an advanced porcine model of cardiac surgery with cardioplegic arrest

  Ascione, R. (Principal Investigator)

  1/12/18 → 31/05/21

  Project: Research

• 8065 MRC via Imperial Vascular constructs using human pluripotent stem cells in the therapy of peripheralarterial disease MR/R0250021/01

  Ascione, R. (Principal Investigator)

  8/10/18 → 7/02/21

  Project: Research

• Building greater capacity for Industry engagement at the TBRC

  Ascione, R. (Principal Investigator)

  1/09/18 → 31/08/19

  Project: Research

• 8064 EBI MRC CiC - Prof Raimondo Ascione

  Ascione, R. (Principal Investigator)

  1/09/18 → 30/06/21

  Project: Research

• BHF grant award in collaboration with Edinburgh (PI Gillian Gray) and Astrazeneca: TAF05 BHF Translational Award

  Ascione, R. (Principal Investigator)

  1/07/18 → 30/09/22

  Project: Research

• 8065 Heart Harvest for Langendorff Experiement - Andy Scott Imperial College (closed)

  Ascione, R. (Principal Investigator)

  1/07/18 → 30/09/18

  Project: Research

• Building a pharma testbed interface with industry for TBRC

  Ascione, R. (Principal Investigator)

  1/05/18 → 31/08/18

  Project: Research

• 8065 MRC VIA CAMBRIDGE MR/M015769/1 MitoSNO extension

  Ascione, R. (Principal Investigator)

  1/04/18 → 30/09/18

  Project: Research

• BHF Centre of Regenerative Medicine (Edinburgh) - Clinical translation of novel therapy

  Ascione, R. (Principal Investigator)

  1/10/17 → 30/06/22

  Project: Research

• Determination of the SK channel composition contributing to atrial action potential duration

  Ascione, R. (Co-Principal Investigator) & Marrion, N. V. (Principal Investigator)

  26/06/17 → 25/06/18

  Project: Research

  • Amino Terminal Sequence 100%
  • Cognitive Disorders 100%
  • Tauopathy 100%
  • Calcium Current 100%
  • C-Terminus 100%

• TBRC: The Succinate in Pigs (SiP) study

  Ascione, R. (Principal Investigator)

  10/06/17 → 9/10/17

  Project: Research

• Bio-engineering of small arterial grafts using acellular vascular matrix from human saphenous veins (SVG) as an alternative to SVG and synthetic grafts for coronary and peripheral vascular surgery.

  Ascione, R. (Principal Investigator)

  1/06/17 → 30/11/20

  Project: Research

• SMARTsurg

  Ascione, R. (Principal Investigator)

  1/02/17 → 31/01/20

  Project: Research, Parent

  • Surgeon 100%
  • Minimally Invasive Procedure 100%
  • Orthopedic Surgery 25%
  • Wearable Sensor 25%
  • Confined Space 25%

• SMARTsurg

  Ascione, R. (Principal Investigator)

  1/01/17 → 30/06/21

  Project: Research

• 8065 H2020 WP1 SMARTsurg 732515

  Ascione, R. (Principal Investigator)

  1/01/17 → 30/06/21

  Project: Research

• Polymeric Prosthetic Heart Valve from anisotropic nanocomposites. Device optimisation and in-vivo testing

  Ascione, R. (Principal Investigator)

  British Heart Foundation

  1/06/15 → 31/05/22

  Project: Research

  • T-Tubule 100%
  • Cardiac Muscle Cell 100%
  • Pig 100%
  • Myocyte 100%
  • Cardiopulmonary Bypass 100%

• MitoSNO - Selective S-nitrosation of mitochondrial complex I by MitoSNO as a new therapy for cardiac ischemia-reperfusion injury

  Ascione, R. (Principal Investigator)

  1/05/15 → 30/09/18

  Project: Research, Parent

• MitoSNO - Selective S-nitrosation of mitochondrial complex I by MitoSNO as a new therapy for cardiac ischemia-reperfusion injury

  Ascione, R. (Principal Investigator)

  Medical Research Council

  1/05/15 → 1/02/19

  Project: Research

• Mathematical bio-modelling of ischemic heart failure following acute MI

  Ascione, R. (Principal Investigator)

  1/03/15 → 28/02/18

  Project: Research

• i4i - Development of a novel clinical platelet analyser

  Ascione, R. (Principal Investigator)

  1/08/14 → 1/08/16

  Project: Research

• Regenerative Medicine Capital - MRC: Pre-Clinical In-Vivo Functional Imaging for Translational Regenerative Medicine

  Ascione, R. (Principal Investigator)

  1/01/14 → 1/01/19

  Project: Research

  • Pig 100%
  • Atrial Fibrillation 66%
  • Heart Surgery 66%
  • Oxidative Stress 66%
  • Vibratome 66%

• SPHERE (EPSRC IRC)

  Craddock, I. J. (Principal Investigator), Coyle, D. T. (Principal Investigator), Flach, P. A. (Principal Investigator), Kaleshi, D. (Principal Investigator), Mirmehdi, M. (Principal Investigator), Piechocki, R. J. (Principal Investigator), Stark, B. H. (Principal Investigator), Ascione, R. (Co-Principal Investigator), Ashburn, A. M. (Collaborator), Burnett, M. E. (Collaborator), Damen, D. (Co-Principal Investigator), Gooberman-Hill, R. (Principal Investigator), Harwin, W. S. (Collaborator), Hilton, G. (Co-Principal Investigator), Holderbaum, W. (Collaborator), Holley, A. P. (Manager), Manchester, V. A. (Administrator), Meller, B. J. (Other ), Stack, E. (Collaborator) & Gilchrist, I. D. (Principal Investigator)

  1/10/13 → 30/09/18

  Project: Research, Parent

  • Energy Engineering 100%
  • Internet-Of-Things 96%
  • Residential Environment 95%
  • Activity Recognition 78%
  • Antenna 59%

• SPHERE (EPSRC IRC)

  Coyle, D. T. (Principal Investigator), Flach, P. A. (Principal Investigator), Kaleshi, D. (Principal Investigator), Mirmehdi, M. (Principal Investigator), Piechocki, R. J. (Principal Investigator), Stark, B. H. (Principal Investigator), Ascione, R. (Co-Principal Investigator), Ashburn, A. M. (Collaborator), Burnett, M. E. (Collaborator), Damen, D. (Co-Principal Investigator), Gooberman-Hill, R. (Researcher), Harwin, W. S. (Collaborator), Hilton, G. (Co-Principal Investigator), Holderbaum, W. (Collaborator), Holley, A. P. (Manager), Manchester, V. A. (Administrator), Meller, B. J. (Other ), Stack, E. (Collaborator), Craddock, I. J. (Principal Investigator) & Gilchrist, I. D. (Principal Investigator)

  1/10/13 → 31/03/19

  Project: Research

• Development of a novel clinical platelet analyser

  Day, J. C. C. (Co-Principal Investigator), Poole, A. W. (Co-Principal Investigator) & Ascione, R. (Co-Principal Investigator)

  1/01/12 → 1/01/13

  Project: Research

  • Platelet 100%
  • Bleeding 100%
  • Antiplatelet 100%
  • Thrombocyte Aggregation 66%
  • Thrombocyte Function 66%

• Lung protection in a pig model of cardiopulmonary bypass and cardioplegic arrest

  Ascione, R. (Principal Investigator)

  1/08/10 → 1/01/13

  Project: Research

  • T-Tubule 100%
  • Cardiac Muscle Cell 100%
  • Pig 100%
  • Myocyte 100%
  • Cardiopulmonary Bypass 100%

• PROPERATIVE VOLUME REPLACEMENT VS. USUAL CARE IN DIABETIC PATIENTS HAVING CABG SURGERY: A RANDOMISED CONTROLLED TRIAL (VERDICT)

  Ascione, R. (Principal Investigator)

  1/08/08 → 1/02/14

  Project: Research

• TRANSPLANTATION OF ENRICHED AUTOLOGOUS BONE-MARROW DERIVED CD133+ CELLS IN PATIENTS HAVING CORONARY SURGERY AFTER STEMI

  Ascione, R. (Principal Investigator)

  1/06/07 → 1/08/13

  Project: Research

  • Angiogenin 100%
  • Cardiac Muscle Cell 100%
  • Stromal Cell-Derived Factor 1 100%
  • Myocardial Infarction 100%
  • Stromal Cell Derived Factor 1 100%

• ON PUMP VS OFF PUMP CORONARY SURGERY

  Ascione, R.

  1/04/01 → 1/04/02

  Project: Research

• British Heart Found PG/200013

  Ascione, R.

  1/01/97 → 1/02/97

  Project: Research