Personal profile
Research interests
The overall aim of my research is to understand the contributions the mammalian cerebellum makes to the control of voluntary limb movements.
The cerebellum is the largest motor structure within the brain and to succeed in this aim would substantially increase knowledge of the way in which movements are controlled, as well as shed light on the functional organization of a major neural structure and the pathways linking it to other parts of the nervous system.
In particular, the climbing fibre pathways connecting the inferior olive (a brainstem nucleus) to the cerebellum play a vital but enigmatic role in the regulation of movements. In the short to medium term a key aim of my work is to test and refine the hypothesis that these connections provide 'error signals' to the cerebellum during performance of both new and well-rehearsed movements.
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Collaborations and top research areas from the last five years
Research output
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Cerebellar cortical organization: a one-map hypothesis
Apps, R. & Hawkes, R., Sept 2009, In: Nature Reviews Neuroscience. 10, 9, p. 670-681 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
419 Citations (Scopus) -
Structural basis of cerebellar microcircuits in the rat
Cerminara, N. L., Aoki, H., Loft, M., Sugihara, I. & Apps, R., 16 Oct 2013, In: Journal of Neuroscience. 33, 42, p. 16427-16442 16 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile40 Citations (Scopus)846 Downloads (Pure) -
Bidirectional Cerebellar Control of Supra-Second Timing in Rats
Boven, E. J. P., Pickford, J., Apps, R. & Cerminara, N. L., 22 Jan 2026, (E-pub ahead of print) In: eNeuro. 13, 2, 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus)
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CEN: 8051 956414 — CEN - H2020 Marie Sklodowska Curie ITN
Apps, R. (Principal Investigator)
1/06/21 → 31/05/25
Project: Research
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Acetylcholine in cerebellar dependent motor learning
Apps, R. (Principal Investigator)
1/01/19 → 30/06/23
Project: Research
Datasets
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Neuronal activity patterns in microcircuits of the cerebellar cortical C3 zone during reaching
Cerminara, N. (Creator), Apps, R. (Creator), Darch, H. (Creator), Houghton, C. (Contributor), Garwicz, M. (Contributor) & Marple-Horvat, D. (Contributor), University of Bristol, 1 Aug 2022
DOI: 10.5523/bris.2kgpk2eeewino2eka4kk8xa61r, http://data.bris.ac.uk/data/dataset/2kgpk2eeewino2eka4kk8xa61r
Dataset
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Frontiers in Systems Neuroscience (Journal)
Apps, R. (Editor)
1 Jan 2024 → 31 Dec 2024Activity: Publication peer-review and editorial work types › Publication peer-review
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Early career investigators’ grant funding workshop: The role of the cerebellum in fear circuits.
Lawrenson, C. L. (Organiser), Apps, R. (Participant), Lumb, B. (Participant) & Paci, E. (Participant)
1 Jul 2018 → 2 Jul 2018Activity: Participating in or organising an event types › Participation in workshop, seminar, course