Research output per year
Research output per year
- 19 results
Search results
-
2024
Contrasting consequences of podocyte insulin-like growth factor 1 receptor inhibition
Hurcombe, J. A., Barrington, F., Marchetti, M., Betin, V. M. S., Bowen, E. E., Lay, A. C., Ni, L., Dayalan, L., Pope, R. J. P., Brinkkoetter, P. T., Holzenberger, M., Welsh, G. I. & Coward, R. J. M., 17 May 2024, In: iScience. 27, 5, 18 p., 109749.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease
Lay, A. C., Tran, V. D. T., Nair, V., Betin, V. M. S., Hurcombe, J. A., Barrington, A. F., Pope, R. J. P., Burdet, F., Mehl, F., Kryvokhyzha, D., Ahmad, A., C. Sinton, M., Lewis, P., Wilson, M. C., Menon, R., Otto, E. A., Heesom, K. J., C. Looker, H., Nelson, R. G. & Ju, W. & 4 others, , 19 Nov 2024, (E-pub ahead of print) In: Nature Communications. 15, 1, 19 p., 10018.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)9 Downloads (Pure) -
2023
Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation
Bowen, E. E., Hurcombe, J. A., Barrington, F., Keir, L. S., Farmer, L. K., Wherlock, M. D., Ortiz-Sandoval, C. G., Bruno, V., Bohorquez-Hernandez, A., Diatlov, D., Rostam-Shirazi, N., Wells, S., Stewart, M., Teboul, L., Lay, A. C., Butler, M. J., Pope, R. J. P., Larkai, E. M. S., Morgan, B. P. & Moppett, J. & 6 others, , 10 Nov 2023, In: Med (New York, N.Y.). 4, 11, p. 761-777.e8Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
2021
IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes
Lay, A. C., Hale, L. J., Stowell-Connolly, H., Pope, R. J. P., Nair, V., Ju, W., Marquez, E., Rollason, R., Hurcombe, J. A., Hayes, B., Roberts, T., Gillam, L., Allington, J., Nelson, R. G., Kretzler, M., Holly, J. M. P., Perks, C. M., McArdle, C. A., Welsh, G. I. & Coward, R. J. M., Jul 2021, In: Diabetologia. 64, 7, p. 1690-1702 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile24 Citations (Scopus)98 Downloads (Pure) -
2020
An information theoretic approach to insulin sensing by human kidney podocytes
Pope, R. J., Garner, K. L., Voliotis, M., Lay, A. C., Betin, V. M., Tsaneva-Atanasova, K., Welsh, G. I., Coward, R. J. & McArdle, C. A., 1 Aug 2020, In: Molecular and Cellular Endocrinology. 518, 110976.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile4 Citations (Scopus)63 Downloads (Pure) -
2013
Galanin stimulates neurite outgrowth from sensory neurons by inhibition of Cdc42 and Rho GTPases and activation of cofilin
Hobson, S., Vanderplank, P. A., Pope, R. J. P., Kerr, N. C. H. & Wynick, D., 2013, In: Journal of Neurochemistry. 127, 2, p. 199-208 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
28 Citations (Scopus) -
RhoG regulates platelet granule secretion and thrombus formation in mice
Goggs, R., Harper, M. T., Pope, R. J., Savage, J. S., Williams, C. M., Mundell, S. J., Heesom, K. J., Bass, M., Mellor, H. & Poole, A. W., 8 Oct 2013, In: Journal of Biological Chemistry.Research output: Contribution to journal › Article (Academic Journal) › peer-review
34 Citations (Scopus) -
2012
ARF6-Dependent Regulation of P2Y Receptor Traffic and Function in Human Platelets
Kanamarlapudi, V., Owens, S. E., Saha, K., Pope, R. J. & Mundell, S. J., 2012, In: PLoS ONE. 7, 8, p. e43532Research output: Contribution to journal › Article (Academic Journal) › peer-review
26 Citations (Scopus) -
Arrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization
Nisar, S. P., Cunningham, M., Saxena, K., Pope, R. J., Kelly, E. & Mundell, S. J., 13 Jul 2012, In: Journal of Biological Chemistry. 287, 29, p. 24505-24515 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
32 Citations (Scopus) -
2010
Characterisation of the nociceptive phenotype of suppressible galanin overexpressing transgenic mice
Pope, R., Holmes, F., Kerr, N. & Wynick, D., Oct 2010, In: Molecular Pain. 6Research output: Contribution to journal › Article (Academic Journal) › peer-review
13 Citations (Scopus) -
Galanin acts as a trophic factor to the central and peripheral nervous systems
Hobson, S., Bacon, A., Elliot-Hunt, C., Holmes, F., Kerr, N., Pope, R., Vanderplank, P. & Wynick, D., 2010, Galanin. Birkhäuser Basel, p. 25 - 38 16 p. (EXS; vol. 102).Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
31 Citations (Scopus) -
The expression of ELK transcription factors in adult DRG: Novel isoforms, antisense transcripts and upregulation by nerve damage
Kerr, N., Pintzas, A., Holmes, F., Hobson, S., Pope, R., Wallace, M., Wasylyk, C., Wasylyk, B. & Wynick, D., 2010, In: Molecular and Cellular Neuroscience. 44, p. 165 - 177Research output: Contribution to journal › Article (Academic Journal) › peer-review
19 Citations (Scopus) -
2009
A role for galanin in human and experimental inflammatory demyelination
Wraith, D., Pope, R., Butzkueven, H., Holder, H., Vanderplank, P., Lowrey, P., Day, M., Gundlach, A., Kilpatrick, T., Scolding, N. & Wynick, D., 8 Sept 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 36, p. 15466 - 15471 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
40 Citations (Scopus) -
2008
Galanin acts as a trophic factor to the central and peripheral nervous systems
Hobson, S., Bacon, A., Elliott-Hunt, C., Holmes, F., Kerr, N., Pope, R., Vanderplank, P. & Wynick, D., 2008, In: Cellular and Molecular Life Sciences. 65, p. 1806 - 1812Research output: Contribution to journal › Article (Academic Journal) › peer-review
51 Citations (Scopus) -
2007
Activation of the galanin receptor 2 (GalR2) protects the hippocampus from neuronal damage
Elliott-Hunt, C., Pope, R., Vanderplank, P. & Wynick, D., Feb 2007, In: Journal of Neurochemistry. 100 (3), p. 780 - 789 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
89 Citations (Scopus) -
2006
Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour
Hobson, S., Holmes, F., Kerr, N., Pope, R. & Wynick, D., Nov 2006, In: Journal of Neurochemistry. 99 (3), p. 1000 - 1010 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
80 Citations (Scopus) -
2004
Galanin acts as a neuroprotective factor to the hippocampus
Elliott-Hunt, C., Marsh, B., Bacon, A., Pope, R., Vanderplank, P. & Wynick, D., 6 Apr 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101 (14), p. 5105 - 5110 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
123 Citations (Scopus) -
2003
Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior
Holmes, F., Bacon, A., Pope, R., Vanderplank, P., Kerr, N., Sukumaran, M., Pachnis, V. & Wynick, D., 13 May 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100 (10), p. 6180 - 6185 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
67 Citations (Scopus) -
2001
Endogenous galanin potentiates spinal nociceptive processing following inflammation
Kerr, B., Gupta, Y., Pope, R., Thompson, S., Wynick, D. & McMahon, S., Sept 2001, In: PAIN. 93 (3), p. 267 - 277 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
44 Citations (Scopus)