Research output per year
Research output per year
B.Sc., Ph.D., D.Sc.(Soton)
BS8 1TD
In the jellyfish Aglantha digitale two forms of swimming arise from two separate propagating axonal impulses; a fast, overshooting action potential that depends on TTX-resistant Na+ channels, and a low amplitude spike that depends on T-type Ca2+ channels. While the Na+ action potential is propagated simply and without distortion, the shape of the Ca2+ spike depends on the past history of the axon; it is processed as well as propagated.
Patch- and voltage-clamp experiments show how three classes of K+ channels contribute to this apparently unique system. Dual Na+/Ca2+ impulses may increase the bandwidth of an axonal line of communication but it also places restrictions on the form of the synaptic input needed for spike initiation.
Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Meech, R. W. (Principal Investigator)
14/12/20 → 13/12/22
Project: Research