Professor Ruth C Massey

  • BS8 1TD

20132020

Research output per year

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Research Output

  • 18 Article (Academic Journal)
2020

A small membrane stabilising protein critical to the pathogenicity of Staphylococcus aureus

Duggan, S., Alnahari, A., Bacon, L., Massey, R. C. & al., E., 9 Jun 2020, (Accepted/In press) In : Infection and Immunity.

Research output: Contribution to journalArticle (Academic Journal)

2019

Genomic identification of cryptic susceptibility to penicillins and β-lactamase inhibitors in methicillin-resistant Staphylococcus aureus

Harrison, E., Ba, X., Coll, F., Blane, B., Restif, O., Carvell, H., Köser, C. U., Jamrozy, D., Reuter, S., Lovering, A. M., Gleadhall, N., Bellis, K. L., Uhlemann, A-C., Lowy, F. D., Massey, R. C., Grilo, I. R., Sobral, R., Larsen, J., Larsen, A. R., Vingsbo Lundberg, C. & 5 others, Parkhill, J., Paterson, G. K., Holden, M. T. G., Peacock, S. J. & Holmes, M. A., 24 Jun 2019, In : Nature Microbiology. 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
90 Downloads (Pure)

Timing Is Everything: Impact of Naturally Occurring Staphylococcus aureus AgrC Cytoplasmic Domain Adaptive Mutations on Autoinduction

Sloan, T. J., Murray, E., Yokoyama, M., Massey, R. C., Chan, W. C., Bonev, B. B. & Williams, P., 15 Oct 2019, In : Journal of Bacteriology. 201, 20, 15 p., e00409-19.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
104 Downloads (Pure)
2018

Disease-associated genotypes of the commensal skin bacterium Staphylococcus epidermidis

Méric, G., Mageiros, L., Pensar, J., Laabei, M., Yahara, K., Pascoe, B., Kittiwan, N., Tadee, P., Post, V., Lamble, S., Bowden, R., Bray, J. E., Morgenstern, M., Jolley, K. A., Maiden, M. C. J., Feil, E. J., Didelot, X., Miragaia, M., de Lencastre, H., Moriarty, T. F. & 5 others, Rohde, H., Massey, R., Mack, D., Corander, J. & Sheppard, S. K., 1 Dec 2018, In : Nature Communications. 9, 1, 11 p., 5034.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
248 Downloads (Pure)

Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA

Yokoyama, M., Stevens, E., Laabei, M., Bacon, L., Heesom, K., Bayliss, S., Ooi, N., O'Neill, A. J., Murray, E., Williams, P., Lubben, A., Reeksting, S., Meric, G., Pascoe, B., Sheppard, S. K., Recker, M., Hurst, L. D. & Massey, R. C., 18 Jul 2018, In : Genome Biology. 19, 12 p., 94.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
145 Downloads (Pure)

Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureusbacteraemia

Giulieri, S. G., Baines, S. L., Guerillot, R., Seemann, T., Gonçalves da Silva, A., Schultz, M., Massey, R. C., Holmes, N. E., Stinear, T. P. & Howden, B. P., 23 Aug 2018, In : Genome Medicine. 10, 17 p., 65.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
209 Downloads (Pure)
2017

Bacterial Toxins: Offensive, Defensive, or something else altogether

Massey, R., 21 Sep 2017, In : PLoS Pathogens.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Citations (Scopus)
233 Downloads (Pure)

Clonal differences in Staphylococcus aureus bacteraemia-associated mortality

Massey, R., Oct 2017, In : Nature Microbiology. 2, 10, p. 1381-1388 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
41 Citations (Scopus)
313 Downloads (Pure)

Cytolytic toxin production by Staphylococcus aureus is dependent upon the activity of the protoheme IX farnesyltransferase

Stevens, E., Massey, R., Laabei, M., Gardner, S. & Somerville, G., 23 Oct 2017, In : Scientific Reports. 7, 7 p., 13744.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
221 Downloads (Pure)

Promiscuous bacteria have staying power

Massey, R. C. & Wilson, D. J., 8 Sep 2017, In : eLife. 6, e30734.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
215 Downloads (Pure)

Severe infections emerge from commensal bacteria by adaptive evolution

Young, B. C., Wu, C-H., Gordon, N. C., Cole, K., Price, J. R., Liu, E., Sheppard, A. E., Perera, S., Charlesworth, J., Golubchik, T., Iqbal, Z., Bowden, R., Massey, R. C., Paul, J., Crook, D. W., Peto, T. E., Walker, A. S., Llewelyn, M. J., Wyllie, D. H. & Wilson, D. J., 19 Dec 2017, In : eLife. 6, 25 p., e30637.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
238 Downloads (Pure)
2015

Evolutionary Trade-Offs Underlie the Multi-faceted Virulence of Staphylococcus aureus

Laabei, M., Uhlemann, A-C., Lowy, F. D., Austin, E. D., Yokoyama, M., Ouadi, K., Feil, E., Thorpe, H. A., Williams, B., Perkins, M., Peacock, S. J., Clarke, S. R., Dordel, J., Holden, M., Votintseva, A. A., Bowden, R., Crook, D. W., Young, B. C., Wilson, D. J., Recker, M. & 1 others, Massey, R. C., 2 Sep 2015, In : PLoS Biology. 13, 9, p. e1002229

Research output: Contribution to journalArticle (Academic Journal)

55 Citations (Scopus)

Manipulation of Autophagy in Phagocytes Facilitates Staphylococcus aureus Bloodstream Infection

O'Keeffe, K. M., Wilk, M. M., Leech, J. M., Murphy, A. G., Laabei, M., Monk, I. R., Massey, R. C., Lindsay, J. A., Foster, T. J., Geoghegan, J. A. & McLoughlin, R. M., Sep 2015, In : Infection and Immunity. 83, 9, p. 3445-3457 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
36 Citations (Scopus)
269 Downloads (Pure)
2014

Characterizing the genetic basis of bacterial phenotypes using genome-wide association studies: a new direction for bacteriology

Read, T. D. & Massey, R. C., 22 Nov 2014, In : Genome Medicine. 6, 11, p. 109

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
43 Citations (Scopus)
193 Downloads (Pure)

Evidence for steric regulation of fibrinogen binding to Staphylococcus aureus fibronectin-binding protein A (FnBPA)

Stemberk, V., Jones, R. P. O., Moroz, O., Atkin, K. E., Edwards, A. M., Turkenburg, J. P., Leech, A. P., Massey, R. C. & Potts, J. R., 2 May 2014, In : Journal of Biological Chemistry. 289, 18, p. 12842-12851 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
15 Citations (Scopus)
143 Downloads (Pure)

Predicting the virulence of MRSA from its genome sequence

Laabei, M., Recker, M., Rudkin, J. K., Aldeljawi, M., Gulay, Z., Sloan, T. J., Williams, P., Endres, J. L., Bayles, K. W., Fey, P. D., Yajjala, V. K., Widhelm, T., Hawkins, E., Lewis, K., Parfett, S., Scowen, L., Peacock, S. J., Holden, M., Wilson, D., Read, T. D. & 6 others, van den Elsen, J., Priest, N. K., Feil, E. J., Hurst, L. D., Josefsson, E. & Massey, R. C., May 2014, In : Genome Research. 24, 5, p. 839-49 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
82 Citations (Scopus)
229 Downloads (Pure)

Staphylococcus aureus interaction with phospholipid vesicles - a new method to accurately determine accessory gene regulator (agr) activity

Laabei, M., Jamieson, W. D., Massey, R. C. & Jenkins, A. T. A., 30 Jan 2014, In : PLoS ONE. 9, 1, 12 p., e87270.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
21 Citations (Scopus)
194 Downloads (Pure)
2013

Oxacillin alters the toxin expression profile of community-associated methicillin-resistant Staphylococcus aureus

Rudkin, J. K., Laabei, M., Edwards, A. M., Joo, H-S., Otto, M., Lennon, K. L., O'Gara, J. P., Waterfield, N. R. & Massey, R. C., 2 Dec 2013, In : Antimicrobial Agents and Chemotherapy. 58, 2, p. 1100-1107 8 p.

Research output: Contribution to journalArticle (Academic Journal)

29 Citations (Scopus)