Dr Sarah J Lewis

B.Sc.(Sheff.), Ph.D.(Manc.)

  • BS8 2BN

19962020

Research output per year

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Research Output

2020

A Mendelian randomization study of the causal association between anxiety phenotypes and schizophrenia

Jones, H. J., Martin, D., Lewis, S. J., Davey Smith, G., O'Donovan, M. C., Owen, M. J., Walters, J. T. R. & Zammit, S., 28 May 2020, (Accepted/In press) In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics.

Research output: Contribution to journalArticle (Academic Journal)

Cleft lip/palate and educational attainment: cause, consequence, or correlation? A Mendelian randomization study

Dardani, C., Howe, L. J. M. S., Mukhopadhyay, N., Stergiakouli, E., Wren, Y. E., Humphries, K. J., Davies, A. J. V., Ho, K. M., Weinberg, S., Marazita, M., Mangold, E., Ludwig, K., Relton, C. L., Davey Smith, G., Lewis, S. J., Sandy, J. R., Davies, N. M. & Sharp, G. C., 25 Feb 2020, (Accepted/In press) In : International Journal of Epidemiology.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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64 Downloads (Pure)

Physical activity and risks of breast and colorectal cancer: A Mendelian randomization analysis

Papadimitriou, N., Dimou, N. L., Tsilidis, K. K., Banbury, B., Martin, R. M., Lewis, S. J., Kazmi, N., Robinson, T. M., Albanes, D., Aleksandrova, K., Berndt, S. I., Bishop, T. D., Brenner, H., Buchanan, D. D., Bueno-de-Mesquita, H. B., Campbell, P. T., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Ellingjord-Dale, M. & 62 others, Figueiredo, J. C., Gallinger, S., Giles, G. G., Giovannucci, E., Gruber, S. B., Gsur, A., Hampe, J., Hampel, H., Harlid, S., Harrison, T. A., Hoffmeister, M., Hopper, J. L., Hsu, L., Huerta, J-M., Huyghe, J. R., Jenkins, M. A., Keku, T. O., Kühn, T., La Vecchia, C., Le Marchand, L., Li, C., Li, L., Lindblom, A., Lindor, N. M., Lynch, B., Markowitz, S., Masala, G., May, A., Milne, R. L., Monninkhof, E., Moreno, L., Moreno, V., Newcomb, P., Offit, K., Perduca, V., Pharoah, P., Platz, E. A., Potter, J. D., Rennert, G., Riboli, E., Sanchez, M-J., Schmit, S. L., Schoen, R. E., Severi, G., Sieri, S., Slattery, M. L., Song, M., Tangen, C. M., Thibodeau, S., Travis, R. C., Trichopoulou, A., Ulrich, C. M., van Duijnhoven, F. J., Van Guelpen, B., Vodicka, P., White, E., Wolk, A., Woods, M., Wu, A. H., Peters, U., Gunter, M. J. & Murphy, N., 30 Jan 2020, In : Nature Communications. 11, 10 p., 597 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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66 Downloads (Pure)
2019
Open Access
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1 Citation (Scopus)
209 Downloads (Pure)

Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate

Howe, L., Richardson, T., Arathimos, R., Alvizi, L., Passos-Bueno, M. R., Stanier, P., Nohr, E. A., Ludwig, K., Mangold, E., Knapp, M., Stergiakouli, E., St Pourcain, B., Davey Smith, G., Sandy, J., Relton, C., Lewis, S., Hemani, G. & Sharp, G., 1 Feb 2019, In : Epigenomics. 11, 2, p. 133-145 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
163 Downloads (Pure)

Genetic evidence for assortative mating on alcohol consumption in the UK Biobank

Howe, L. J., Lawson, D. J., Davies, N. M., St. Pourcain, B., Lewis, S. J., Davey Smith, G. & Hemani, G., 19 Nov 2019, In : Nature Communications. 10, 10 p., 5039 (2019).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
132 Downloads (Pure)

Physical activity during the school holidays: Parent perceptions and practical considerations

Collison, L., Lewis, S., Reid, T., Matthews, J., Sebire, S., Thompson, J. & Jago, R., 14 May 2019, In : International Journal of Environmental Research and Public Health. 16, 10, 14 p., 1697.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
120 Downloads (Pure)

Prenatal alcohol exposure and facial morphology in a UK cohort

Howe, L. J., Sharp, G. C., Hemani, G., Zuccolo, L., Richmond, S. & Lewis, S. J., 1 Apr 2019, In : Drug and Alcohol Dependence. 197, p. 42-47 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
60 Downloads (Pure)

Sex hormone binding globulin and risk of breast cancer: A Mendelian randomization study

Dimou, N. L., Papadimitriou, N., Gill, D., Christakoudi, S., Murphy, N., Gunter, M. J., Travis, R. C., Key, T. J., Fortner, R. T., Haycock, P. C., Lewis, S. J., Muir, K., Martin, R. M. & Tsilidis, K. K., 29 May 2019, In : International Journal of Epidemiology. 48, 3, p. 807-816 10 p., dyz107.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
41 Downloads (Pure)
Open Access
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117 Downloads (Pure)
2018
Open Access
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14 Citations (Scopus)
134 Downloads (Pure)

Circulating selenium and prostate cancer risk: A mendelian randomization analysis

Yarmolinsky, J., Bonilla, C., Haycock, P., Langdon, R., Lotta, L. A., Langenberg, C., Relton, C., Lewis, S., Evans, D., Davey Smith, G. & Martin, R., Sep 2018, In : Journal of the National Cancer Institute. 110, 9, p. 1035-1038 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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12 Citations (Scopus)
212 Downloads (Pure)

Circulating vitamin D concentrations and risk of breast and prostate cancer: a Mendelian randomization study

Jiang, X., Dimou, N. L., Al-Dabhani, K., Lewis, S., Martin, R., Haycock, P., Gunter, M. J., Key, T. J., Eeles, R. A., Muir, K., Neal, D., Giles, G. G., Giovannucci, E. L., Stampfer, M. J., Pierce, B., Schildkraut, J., Andersen, S., Thompson, D. J., Zheng, W., Kraft, P. & 1 others, Tsilidis, K., 28 Dec 2018, In : International Journal of Epidemiology. 9 p., dyy284.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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7 Citations (Scopus)
104 Downloads (Pure)

Exploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans

Cho, Y., Kwak, S., Lewis, S. J., Wade, K. H., Relton, C. L., Smith, G. D. & Shin, M-J., 11 Jan 2018, In : Scientific Reports. 8, 1, 8 p., 458.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
194 Downloads (Pure)

Facial Genetics: A Brief Overview: A Brief Overview

Richmond, S., Howe, L. J., Lewis, S., Stergiakouli, E. & Zhurov, A., 16 Oct 2018, In : Frontiers in Genetics. 9, p. 462

Research output: Contribution to journalReview article (Academic Journal)

12 Citations (Scopus)

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

the PRACTICAL Consortium, 11 Jun 2018, In : Nature Communications. 9, 1, 19 p., 2256.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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21 Citations (Scopus)
203 Downloads (Pure)

Influence of maternal and own genotype at tanning dependence-related SNPs on sun exposure in childhood

Khouja, J., Lewis, S. & Bonilla, C., 12 Apr 2018, In : BMC Medical Genetics. 19, 1, 8 p., 62.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
190 Downloads (Pure)

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology

Howe, L. J., Lee, M. K., Sharp, G. C., Davey Smith, G., St Pourcain, B., Shaffer, J. R., Ludwig, K. U., Mangold, E., Marazita, M. L., Feingold, E., Zhurov, A., Stergiakouli, E., Sandy, J., Richmond, S., Weinberg, S. M., Hemani, G. & Lewis, S. J., 1 Aug 2018, In : PLoS Genetics. 14, 8, 18 p., e1007501.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
241 Downloads (Pure)

Maternal iron status during pregnancy and respiratory and atopic outcomes in the offspring: a Mendelian randomization study

Bedard, A., Lewis, S., Burgess, S., Henderson, J. & Shaheen, S., 2018, In : BMJ Open Respiratory Research. 30, 5, 10 p., e000275.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
119 Downloads (Pure)

Mendelian randomization does not support serum calcium in prostate cancer risk

Yarmolinsky, J., Berryman, K., Langdon, R., Bonilla, C., the PRACTICAL Consortium, Davey Smith, G., Martin, R. & Lewis, S., 10 Oct 2018, In : Cancer Causes and Control. 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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177 Downloads (Pure)

Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study

Sun, Y-Q., Brumpton, B., Bonilla, C., Lewis, S., Burgess, S., Skorpen, F., Chen, Y., Nilsen, T. I., Romundstad, P. & Mai, X-M., 7 Jun 2018, In : European Respiratory Journal. 51, 6

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
54 Downloads (Pure)
2017

Association of timing of menarche with depressive symptoms and depression in adolescence: Mendelian randomisation study

Sequeira, M-E., Lewis, S. J., Bonilla, C., Davey Smith, G. & Joinson, C., Jan 2017, In : British Journal of Psychiatry. 210, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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26 Citations (Scopus)
230 Downloads (Pure)

Circulating vitamin D concentration and risk of seven cancers: a Mendelian randomization study

Dimitrakopoulou, V. I., GECCO, the PRACTICAL Consortium, GAME-ON Network, CORECT, DRIVE, ELLIPSE, FOCI-OCAC & TRICL-ILLCO, 31 Oct 2017, In : BMJ. 359, 12 p., j4761.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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257 Downloads (Pure)
Open Access
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5 Citations (Scopus)
204 Downloads (Pure)

Distinct DNA methylation profiles in subtypes of orofacial cleft

Sharp, G., Ho, K., Davies, A., Stergiakouli, E., Humphries, K., McArdle, W., Sandy, J., Davey Smith, G., Lewis, S. & Relton, C., 8 Jun 2017, In : Clinical Epigenetics. 9, 63, 18 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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26 Citations (Scopus)
211 Downloads (Pure)

Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis

Harrison, S., Lennon, R., Holly, J. M. P., Higgins, J., Gardner, M. P., Perks, C., Gaunt, T., Tan, V., Borwick, C., Emmett, P., Jeffreys, M., Northstone, K., Rinaldi, S., Thomas, S., Turner, S., Pease, A., Vilenchik, V., Martin, R. & Lewis, S., Jun 2017, In : Cancer Causes and Control. 28, 6, p. 497–528 32 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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23 Citations (Scopus)
378 Downloads (Pure)
Open Access
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217 Downloads (Pure)
Open Access
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46 Citations (Scopus)
260 Downloads (Pure)

Setting up a cohort study in speech and language therapy: lessons from The UK Cleft Collective Speech and Language (CC-SL) study

Wren, Y., Humphries, K., Stock, N. M., Rumsey, N., Lewis, S., Davies, A., Bennett, R. & Sandy, J., 18 Dec 2017, In : International Journal of Language and Communication Disorders. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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243 Downloads (Pure)
Open Access
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22 Citations (Scopus)
274 Downloads (Pure)
2016

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: genetic variants as instruments for circulating levels.

Bonilla, C., Lewis, S., Rowlands, M-A., Gaunt, T., Davey Smith, G., Gunnell, D., Palmer, T., Donovan, J., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A. & 22 others, Schleutker, J., Nordestgaard, B. G., Travis, R. C., Pashayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., The PRACTICAL, C., Lathrop, M., Martin, R. & Holly, J., 1 Oct 2016, In : International Journal of Cancer. 139, 7, p. 1520-1533 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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7 Citations (Scopus)
349 Downloads (Pure)

Blood lipids and prostate cancer: a Mendelian randomization analysis

Bull, C. J., Bonilla, C., Holly, J. M. P., Perks, C. M., Davies, N., Haycock, P., Yu, O. H. Y., Richards, J. B., Eeles, R., Easton, D., Kote-Jarai, Z., Amin Al Olama, A., Benlloch, S., Muir, K., Giles, G. G., MacInnis, R. J., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J. & 23 others, Nordestgaard, B. G., Travis, R. C., Neal, D., Pashayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Micheal, A., Pandha, H., Smith, G. D., Lewis, S. J., Martin, R. M. & the PRACTICAL Consortium, Jun 2016, In : Cancer Medicine. 5, 6, p. 1125-1136 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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20 Citations (Scopus)
222 Downloads (Pure)

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

Bonilla, C., Lewis, S. J., Martin, R. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, B. G., Travis, R. C., Pashayan, N. & 17 others, Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Lathrop, M., Davey Smith, G. & the PRACTICAL Consortium, 4 Apr 2016, In : BMC Medicine. 14, 1, 66.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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17 Citations (Scopus)
230 Downloads (Pure)
2015
25 Citations (Scopus)

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

Davies, N. M., Gaunt, T. R., Lewis, S. J., Holly, J. M. P., Donovan, J. L., Hamdy, F. C., Kemp, J. P., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, B. G., Travis, R. C. & 20 others, Neal, D., Pashayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Lathrop, M., Davey Smith, G., Martin, R. M. & the PRACTICAL Consortium, Nov 2015, In : Cancer Causes and Control. 26, p. 1603-1616 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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34 Citations (Scopus)
291 Downloads (Pure)
2014

Adverse effects from antidepressant treatment: randomised controlled trial of 601 depressed individuals

Crawford, A. A., Lewis, S., Nutt, D., Peters, T. J., Cowen, P., O'Donovan, M. C., Wiles, N. & Lewis, G., Aug 2014, In : Psychopharmacology. 231, 15, p. 2921-31 11 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)

Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population

Crawford, A., Dalvie, S., Lewis, S., King, A., Liberzon, I., Fein, G., Koenen, K., Ramesar, R. & Stein, D. J., Jun 2014, In : Metabolic Brain Disease. 29, 2, p. 333-40 8 p.

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)
10 Citations (Scopus)
25 Citations (Scopus)
2013

Alcohol consumption and PSA-detected prostate cancer risk-A case-control nested in the ProtecT study

Zuccolo, L., Lewis, S. J., Donovan, J. L., Hamdy, F. C., Neal, D. E. & Smith, G. D., 2013, In : International Journal of Cancer. 132, 9, p. 2176-2185 10 p.

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)
17 Citations (Scopus)
Open Access
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83 Citations (Scopus)
353 Downloads (Pure)

Effect of Prenatal Alcohol Exposure on Childhood Academic Outcomes: Contrasting Maternal and Paternal Associations in the ALSPAC Study

Alati, R., Smith, G. D., Lewis, S. J., Sayal, K., Draper, E. S., Golding, J., Fraser, R. & Gray, R., 9 Oct 2013, In : PLoS ONE. 8, 10, 9 p., 74844.

Research output: Contribution to journalArticle (Academic Journal)

29 Citations (Scopus)

Prenatal alcohol exposure and offspring cognition and school performance: a 'Mendelian randomization' natural experiment.

Zuccolo, L., Lewis, S. J., Smith, G. D., Sayal, K., Draper, E. S., Fraser, R., Barrow, M., Alati, R., Ring, S., Golding, J., Heron, J., Gray, R. & Macleod, J. A. A., Oct 2013, In : International Journal of Epidemiology. 42, 5, p. 1358-1370 13 p.

Research output: Contribution to journalArticle (Academic Journal)

49 Citations (Scopus)

Using Genetic Proxies for Lifecourse Sun Exposure to Assess the Causal Relationship of Sun Exposure with Circulating Vitamin D and Prostate Cancer Risk

Bonilla, C., Gilbert, R., Kemp, J. P., Timpson, N. J., Evans, D. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Fraser, W. D., Smith, G. D., Lewis, S. J., Lathrop, M., Martin, R. M. & Gilbert, R., Apr 2013, In : Cancer Epidemiology, Biomarkers and Prevention. 22, 4, p. 597-606 10 p.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)
2012

Fetal Alcohol Exposure and IQ at Age 8: Evidence from a Population-Based Birth-Cohort Study

Lewis, S. J., Zuccolo, L., Davey Smith, G., Macleod, J. A. A., Rodriguez, S., Draper, E. S., Barrow, M., Alati, R., Sayal, K., Ring, S., Golding, J. & Gray, R., Nov 2012, In : PLoS ONE. 7, 11, p. e49407

Research output: Contribution to journalArticle (Academic Journal)

62 Citations (Scopus)