Dr Sean Harrison

BA (Hons)

  • BS8 2BN

20082020

Research output per year

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Personal profile

Research interests

My current work, with Laura Howe and Neil Davies, uses Mendelian Randomization to examine the effect of health conditions and risk factors on socioeonomic outcomes. This work is part of the Health Foundation's project, entitled: "Social and economic consequences of health: causal inference methods and longitudinal, intergenerational data".

The aim of my PhD was to determine if individual characteristics can be identified that are associated both with prostate cancer and PSA. The main analyses included a systematic review with standard and individual participant data meta-analyses, with Mendelian Randomization providing additional information.

I have developed a novel method of synthesising data that can't be meta-analysed - the albatross plot - which has been used in several different contexts.

In the future, I aim to continue using evidence synthesis to answer clinical questions, and to develop automation methods that speed-up the process. 

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Projects

Research Output

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

Brumpton, B., Sanderson, E., Hartwig, F. P., Harrison, S., Cho, Y., Howe, L. D., Hughes, A., Havdahl, A., Howe, L., Morris, T., Windmeijer, F., Evans, D. M., Davey Smith, G., Hemani, G., Davies, N. M. & al., E., 12 Jun 2020, (Accepted/In press) In : Nature Communications.

Research output: Contribution to journalArticle (Academic Journal)

  • Mendelian Randomization analysis of the causal effect of adiposity on hospital costs

    Dixon, P., Hollingworth, W., Harrison, S., Davies, N. M. & Davey Smith, G., 1 Mar 2020, In : Journal of Health Economics. 70, 22 p., 102300.

    Research output: Contribution to journalArticle (Academic Journal)

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