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Dr Sian M Noble

B.Sc., Ph.D.(Bristol)

  • BS8 1NU

20002020

Research output per year

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Personal profile

Research interests

I’m involved in assessing the cost-effectiveness of interventions in a wide range of randomised controlled trials. Recent and current trials include: investigating the feasibility of using CBT during pregnancy; The ProtecT trial of treatments for localised prostate cancer; The CAP study of population level PSA testing; The ROMIO feasibility study, preparing for a trial of surgical techniques for oesophagectomy. The APEX trial which is evaluating the use of local anaesthetic wound infiltration during Total Joint replacement surgery to reduce long term pain, and School based interventions in relation to: Hand washing to reduce pupil and staff absenteeism; an exercise and nutrition intervention to improve and a CBT based intervention to improve depressive symptoms in Chilean schoolchildren.

My methodological research interests stems from the challenges of conducting and analysing economic evaluations alongside randomised controlled trials. I have a particular interest in the prevention of missing data, through the improvement of resource use questionnaire design and the use of routine data.

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Projects

ProtecT Study: 8071 Dept of Health 96/20/99 Original ProtecT code

Neal, D. E., Hamdy, F. C., Davies, C. F., Davis, M. J., Down, E. A., Harrison, S., Hill, L., Khazragui, H. F., Lane, A. A., Metcalfe, C., Noble, S. M., Peters, T., Taylor, H. J., Turner, E. L., Wade, J., Walsh, E. I. & Donovan , J. L.

1/06/08 → 30/06/21

Project: Research

The use of the RUL in reducing recall bias

Noble, S. M.

1/06/13 → 1/12/14

Project: Research

Research Output

  • 70 Article (Academic Journal)
  • 1 Commissioned report

Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

Hamdy, F. C., Donovan, J. L., Lane, J. A., Mason, M., Metcalfe, C., Holding, P., Wade, J., Noble, S., Garfield, K., Young, G., Davis, M., Peters, T. J., Turner, E. L., Martin, R. M., Oxley, J., Robinson, M., Staffurth, J., Walsh, E., Blazeby, J., Bryant, R. & 16 others, Bollina, P., Catto, J., Doble, A., Doherty, A., Gillatt, D., Gnanapragasam, V., Hughes, O., Kockelbergh, R., Kynaston, H., Paul, A., Paez, E., Powell, P., Prescott, S., Rosario, D., Rowe, E. & Neal, D., 28 Jul 2020, (Accepted/In press) In : Health technology assessment (Winchester, England). 24, 37, p. 1-176 176 p.

Research output: Contribution to journal › Article (Academic Journal)

Open Access
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    • 26 Downloads (Pure)

    Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey

    Thorn, J. C., Hollingworth, W., Noble, S. M. & Davies, C. F., 1 Oct 2020, (Accepted/In press) In : Value in Health.

    Research output: Contribution to journal › Article (Academic Journal)

    2 Downloads (Pure)

    Diagnostic Assessment of Lower Urinary Tract Symptoms in Men Considering Prostate Surgery: A Noninferiority Randomised Controlled Trial of Urodynamics in 26 Hospitals

    Drake, M. J., Lewis, A. L., Young, G., Abrams, P. H., Blair, P. S., Chapple, C., Glazener, C., Horwood, J. P., McGrath, J., Noble, S. M., Taylor, G. & Lane, J. A., 30 Jun 2020, In : European Urology. 10 p.

    Research output: Contribution to journal › Article (Academic Journal)