1988 …2020

Research output per year

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Research Output

Article (Academic Journal)

ABCG4: a novel human white family ABC-transporter expressed predominantly in the brain and eye

Oldfield, S., Lowry, CA., Ruddick, JP. & Lightman, SL., 2002, In : Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1591, p. 175 - 179

Research output: Contribution to journalArticle (Academic Journal)

A better use of corticosteroids

Andrews, RC. & Lightman, SL., 2000, In : Practitioner. 244, p. 667 - 667 1 p.

Research output: Contribution to journalArticle (Academic Journal)

ACTH-Dependent Ultradian Rhythm of Corticosterone Secretion

Spiga, F., Waite, EJ., Liu, Y., Kershaw, YM., Aguilera, G. & Lightman, SL., Apr 2011, In : Endocrinology. 152(4), p. 1448 - 1457

Research output: Contribution to journalArticle (Academic Journal)

69 Citations (Scopus)

Activation of specific ATP receptors induces a rapid increase in intracellular calcium ions in rat hypothalamic neurons

Chen, Z-P., Levy, A. & Lightman, SL., 1994, In : Brain Research. 641, p. 249 - 256 7 p.

Research output: Contribution to journalArticle (Academic Journal)

53 Citations (Scopus)

Activation of the hypothalamo-pituitary axis in adrenalectomized rats: potentiation by chronic stress

Marti, O., Harbuz, MS., Andres, R., Lightman, SL. & Armario, A., 1999, In : Brain Research. 821, p. 1 - 7

Research output: Contribution to journalArticle (Academic Journal)

Activation of the Orexin 1 Receptor Is a Critical Component of CO(2)-Mediated Anxiety and Hypertension but not Bradycardia

Johnson, PL., Samuels, BC., Fitz, SD., Lightman, SL., Lowry, CA. & Shekhar, A., Mar 2012, In : Neuropsychopharmacology.

Research output: Contribution to journalArticle (Academic Journal)

62 Citations (Scopus)

Acute carbon dioxide exposure in healthy adults: evaluation of a novel means of investigating the stress response

Kaye, J., Buchanan, F., Kendrick, A., Johnson, P., Lowry, CA., Bailey, JE., Nutt, DJ. & Lightman, SL., 2004, In : Journal of Neuroendocrinology. 16, p. 256 - 264 (3).

Research output: Contribution to journalArticle (Academic Journal)

89 Citations (Scopus)

Acute Glucocorticoid Administration Rapidly Suppresses Basal and Stress-Induced Hypothalamo-Pituitary-Adrenal Axis Activity

Andrews, MH., Wood, SA., Windle, RJ., Lightman, SL. & Ingram, CD., Jan 2012, In : Endocrinology. 153(1), p. 200 - 211 12 p.

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)

Acute hypercarbic gas exposure reveals functionally distinct subpopulations of serotonergic neurons in rats

Johnson, P., Hollis, JH., Moratalla, R., Lightman, SL. & Lowry, CA., Jul 2005, In : Journal of Psychopharmacology. 19 (4), p. 327 - 341 16 p.

Research output: Contribution to journalArticle (Academic Journal)

60 Citations (Scopus)

Acute stress causes rapid synaptic insertion of Ca2+ -permeable AMPA receptors to facilitate long-term potentiation in the hippocampus

Whitehead, G., Jo, J., Hogg, E. L., Piers, T., Kim, D-H., Seaton, G., Seok, H., Bru-Mercier, G., Son, G. H., Regan, P. L., Hildebrandt, L., Waite, E., Kim, B-C., Kerrigan, T. L., Kim, K., Whitcomb, D. J., Collingridge, G. L., Lightman, S. L. & Cho, K., Dec 2013, In : Brain. 136, 12, p. 3753-3765 13 p.

Research output: Contribution to journalArticle (Academic Journal)

48 Citations (Scopus)

Adaptive changes in basal and stress-induced HPA activity in lactating and post-lactating female rats

Windle, R. J., Wood, S. A., Kershaw, Y. M., Lightman, S. L. & Ingram, C. D., Feb 2013, In : Endocrinology. 154, 2, p. 749-61 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Adrenalectomy further suppresses the NT-3 mRNA response to traumatic brain injury but this effect is not reversed with corticosterone

Grundy, PL., Patel, N., Harbuz, MS., Lightman, SL. & Sharples, PM., 2004, In : Molecular Brain Research. 120, p. 188 - 192 (2).

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)

Adverse early life experience and social stress during adulthood interact to increase serotonin transporter mRNA expression

Gardner, K. L., Hale, M. W., Lightman, S. L., Plotsky, P. M. & Lowry, C. A., 11 Dec 2009, In : Brain Research. 1305, p. 47-63 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus

Gardner, K. L., Hale, M. W., Oldfield, S., Lightman, S. L., Plotsky, P. M. & Lowry, C. A., 10 Nov 2009, In : Neuroscience. 163, 4, p. 991-1001 11 p.

Research output: Contribution to journalArticle (Academic Journal)

79 Citations (Scopus)

A glucocorticoid sensitive biphasic rhythm of testosterone secretion

Waite, EJ., Kershaw, YM., Spiga, F. & Lightman, SL., Sep 2009, In : Journal of Neuroendocrinology. 21, p. 737 - 741

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)
12 Citations (Scopus)

Alterations in hypothalamic-pituitary-adrenal function correlated with the onset of murine SLE in MRL +/+ and lpr/lpr mice

Shanks, NM., Moore, PM., Perks, PA. & Lightman, SL., 1999, In : Brain, Behavior, and Immunity. 13, p. 348 - 360

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Altered glucocorticoid immunoregulation in treatment resistant depression

Bauer, ME., Papadopoulos, A., Poon, L., Perks, P., Lightman, SL., Checkley, S. & Shanks, NM., 2003, In : Psychoneuroendocrinology. 28, p. 48 - 65

Research output: Contribution to journalArticle (Academic Journal)

64 Citations (Scopus)

Anatomical and functional evidence for a stress-responsive, monoamine-accumulating area in the dorsomedial hypothalamus of adult rat brain

Lowry, CA., Plant, A., Shanks, NM., Ingram, CD. & Lightman, SL., Jan 2003, In : Hormones and Behavior. 43 (1), p. 254 - 262 9 p.

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)

A neurodevelopmental model for anorexia nervosa

Connan, F., Campbell, JC., Katzman, M., Lightman, SL. & Treasure, J., 2003, In : Physiology and Behavior. 79, p. 13 - 24

Research output: Contribution to journalArticle (Academic Journal)

171 Citations (Scopus)

A new test for autonomic cardiovascular and neuroendocrine responses in diabetes mellitus: evidence for early vagal dysfunction

Kaye, JM., Corrall, RJM. & Lightman, SL., Jan 2005, In : Diabetologia. 48 (1), p. 180 - 186 7 p.

Research output: Contribution to journalArticle (Academic Journal)

12 Citations (Scopus)

An investigation into the effects of social evaluation on cardiovascular and endocrine responses to the CO2 stress test in humans

Vedhara, K., Brant, H. D., Alexiou, A., Petrie, KJ., Miles, JNV. & Lightman, S. L., 2010, In : Stress. 13, 3, p. 195-202

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)

An investigation into the relationship between salivary cortisol, stress, anxiety, and depression

Vedhara, K., Miles, J., Bennett, PN., Plummer, S., Tallon, D., Brooks, E., Gale, L., Munnock, K., Schreiber-Kounine, C., Fowler, C., Lightman, SL., Sammon, A., Rayter, Z. & Farndon, J., Feb 2003, In : Biological Psychology. 62 (2), p. 89 - 96 8 p.

Research output: Contribution to journalArticle (Academic Journal)

An investigation of hypothalamic-pituitary-adrenal axis hyperactivity in anorexia nervosa: the role of CRH and AVP

Connan, F., Lightman, SL., Landau, S., Wheeler, M., Treasure, J. & Campbell, IC., Jan 2007, In : Journal of Pyschiatric Research. 41 (1-2), p. 131 - 143

Research output: Contribution to journalArticle (Academic Journal)

56 Citations (Scopus)

A novel prednisolone suppression test for the hypothalamic-pituitary-adrenal axis

Pariante, CM., Pappadopoulos, AS., Poon, L., Checkley, SA., English, J., Kerwin, RW. & Lightman, SL., 1 Jun 2002, In : Biological Psychiatry. 51 (11), p. 922 - 930 9 p.

Research output: Contribution to journalArticle (Academic Journal)

59 Citations (Scopus)

Anterior pituitary cell population control: basal cell turnover and the effects of adrenalectomy and dexamethasone treatment

Nolan, LA., Kavanagh, E., Lightman, SL. & Levy, A., 1998, In : Journal of Neuroendocrinology. 10, p. 207 - 215

Research output: Contribution to journalArticle (Academic Journal)

101 Citations (Scopus)

A pilot exploration of heart rate variability and salivary cortisol responses to compassion-focused imagery.

Rockliff, H., Gilbert, P., McEwan, K., Lightman, S. & Glover, D., 2008, In : Clinical Neuropsychiatry: Journal of Treatment Evaluation. 5, 3, p. 132-139

Research output: Contribution to journalArticle (Academic Journal)

Are adhesion molecules involved in stress-induced changes in lymphocyte distribution?

Bauer, ME., Perks, PA., Lightman, SL. & Shanks, NM., 2001, In : Life Sciences. 69, p. 1167 - 1179

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Are tuberomammillary histaminergic neurons involved in CO2 mediated arousal?

Johnson, P., Moratalla, R., Lightman, SL. & Lowry, CA., 2005, In : Experimental Neurology. 193(1), p. 228 - 233 6 p.

Research output: Contribution to journalArticle (Academic Journal)

27 Citations (Scopus)

Arginine vasopressin secretion in Kenyan children with severe malaria

Sowunmi, A., Newton, CRJC., Waruiru, C., Lightman, SL. & Dunger, DB., 2000, In : Journal of Tropical Pediatrics. 46, p. 195 - 199

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

A role for the medial preoptic area in CGRP-induced suppression of pulsatile LH secretion in the female rat

Li, X. F., Kinsey-Jones, J. S., Bowe, J. E., Wilkinson, E. S., Brain, S. D., Lightman, S. L. & O'Byrne, K. T., May 2009, In : Stress. 12, 3, p. 259-67 9 p.

Research output: Contribution to journalArticle (Academic Journal)

A simple complex case: Restoration of circadian cortisol activity

Bhake, R. & Lightman, S., 2015, In : AIMS Medical Science. 2, 3, p. 182-185

Research output: Contribution to journalArticle (Academic Journal)

A simple test for growth hormone deficiency in adults

Mahajan, TA. & Lightman, SL., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, p. 1473 - 1476 4.

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)

A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system

Lopes, M. W., Leal, R. B., Guarnieri, R., Schwarzbold, M. L., Hoeller, A. A., Diaz, A. P., Boos, G., Lin, K., Linhares, M. N., Nunes, J. C., Quevedo, J., Bortolotto, Z. A., Markowitsch, H. J., Lightman, S. L. & Walz, R., Dec 2016, In : Translational Psychiatry. 6, 12, 9 p., e986.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
227 Downloads (Pure)

Assessing viral gene therapy in neuroendocrine models

Geddes, BJ., Harding, TC., Lightman, SL. & Uney, JB., 1999, In : Frontiers in Neuroendocrinology. 20, p. 296 - 316

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)

Assessing viral gene therapy in nneuroendocrine models

Geddes, BJ., Harding, TC., Lightman, SL. & Uney, JB., 1999, In : Frontiers in Neuroendocrinology. 20, p. 296 - 316

Research output: Contribution to journalArticle (Academic Journal)

ATP-mediated killing of Mycobacterium bovis bacille calmette-Guerin within human macrophages is calcium dependent and associated with the acidification of mycobacteria-containing phagosomes

Stober, CB., Lammas, DA., Cheuk, ML., Dinikantha, S., Kumararatne, S., Lightman, SL. & McArdle, CA., 2001, In : Journal of Immunology. 166, p. 6276 - 6286

Research output: Contribution to journalArticle (Academic Journal)

68 Citations (Scopus)
38 Citations (Scopus)

Atypical depression in growth hormone deficient adults, and the beneficial effects of growth hormone treatment on depression and quality of life

Mahajan, TA., Crown, AL., Checkley, S., Farmer, A. & Lightman, SL., 2004, In : European Journal of Endocrinology. 151, p. 325 - 332

Research output: Contribution to journalArticle (Academic Journal)

46 Citations (Scopus)

Automated 24-hours sampling of subcutaneous tissue free cortisol in humans

Bhake, R. C., Leendertz, J. A., Linthorst, A. C. E. & Lightman, S. L., Apr 2013, In : Journal of Medical Engineering and Technology. 37, 3, p. 180-4 5 p.

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA.

Pooley, J., Rivers, C. A., Kilcooley, M., Paul, S. N., Cavga, A. D., Kershaw, Y. M., Muratcioglu, S., Gursoy, A., Keskin, O. & Lightman, S. L., 10 Jan 2020, In : PLoS ONE. 15, 1, 35 p., e0227520.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
53 Downloads (Pure)

Biochemical cure of recurrent acromegaly by resection of cervical spinal canal metastases

Dayan, CM., Guilding, T., Hearing, SD., Thomas, P., Nelson, RJ., Moss, TH., Bradshaw, JR., Levy, A. & Lightman, SL., 1996, In : Clinical Endocrinology. 44, p. 597 - 602

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)

Blockade of the V(1b) receptor reduces ACTH, but not corticosterone secretion induced by stress without affecting basal hypothalamic-pituitary-adrenal axis activity

Spiga, F., Harrison, L., Wood, SA., Knight, DM., MacSweeney, CP., Thomson, FJ., Craighead, M. & Lightman, SL., Mar 2009, In : Journal of Endocrinology. 200(3), p. 273 - 283

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals

Turton, S., Myers, J. F. M., Mick, I., Colasanti, A., Venkataraman, A., Durant, C., Waldman, A., Brailsford, A., Parkin, M. C., Dawe, G., Rabiner, E. A., Gunn, R. N., Lightman, S. L., Nutt, D. J. & Lingford-Hughes, A., 25 Jun 2018, In : Molecular Psychiatry. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
207 Downloads (Pure)

Bromocriptine reduces rat thyrotropin beta-subunit mRNA stability

Levy, A. & Lightman, S. L., Jan 1990, In : Journal of Endocrinological Investigation. 13, 1, p. 49-53 5 p.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

Can nerve damage disrupt neuroendocrine immune homeostasis? Leprosy as a case in point

Rook, GAW., Lightman, SL. & Heijnen, CJ., 2002, In : Trends in Immunology. 23, p. 18 - 22

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

Can side effects of steroid treatments be minimized by the temporal aspects of delivery method?

Russell, G. M. & Lightman, S. L., 26 Sep 2014, In : Expert opinion on drug safety. 13, 11, p. 1501-13

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Changes in the maternal hypothalamic-pituitary-adrenal axis during the early puerperium may be related to the postpartum 'blues'

O'Keane, V., Lightman, S., Patrick, K., Marsh, M., Papadopoulos, A. S., Pawlby, S., Seneviratne, G., Taylor, A. & Moore, R., Nov 2011, In : Journal of Neuroendocrinology. 23, 11, p. 1149-55 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Characterisation of c-Fos expression in the central nervous system of mice following right atrial injections of the 5-HT3 receptor agonist phenylbiguanide

de Vries, A., Paton, JFR., Lightman, SL. & Lowry, CA., 14 Oct 2005, In : Autonomic Neuroscience: Basic and Clinical. 123, p. 62 - 75 14 p.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)