1988 …2020

Research output per year

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Research Output

2000

GABAA receptor mediated elevation of Ca2+ and modulation of gonadotropin-releasing hormone action in αT3-1 gonadotropes

Williams, B., Bence, M., Everest, HM., Forrest-Owen, WF., Lightman, SL. & McArdle, CA., 2000, In : Journal of Neuroendocrinology. 12, p. 159 - 166

Research output: Contribution to journalArticle (Academic Journal)

12 Citations (Scopus)

Glucocorticoids modulate BDNF mRNA expression in the rat hippocampus after traumatic brain injury

Grundy, PL., Patel, N., Harbuz, MS., Lightman, SL. & Sharples, PM., 2000, In : NeuroReport. 11, p. 3381 - 3384 15.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)

Impulsiveness and the prolactin response to d-fenfluramine

Evans, J., Platt, HF., Lightman, SL. & Nutt, DJ., 2000, In : Psychopharmacology. 149, p. 147 - 152

Research output: Contribution to journalArticle (Academic Journal)

30 Citations (Scopus)

Local regulation of glucocorticoid activity in sites of inflammation

Rook, G., Baker, R., Walker, B., Honour, J., Jessop, DS., Hernandez-Pando, R., Arriaga, K., Shaw, R., Zumla, A. & Lightman, SL., 2000, In : Annals of the New York Academy of Sciences. 917, p. 913 - 922

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

Local regulation of glucocorticoid activity in sites of inflammation: insights from the study of tuberculosis

Rook, G., Baker, R., Walker, B., Honour, J., Jessop, DS., Hernandez-Pando, R., Arriaga, K., Shaw, R., Zumla, A. & Lightman, SL., 2000, In : Annals of the New York Academy of Sciences. 917, p. 913 - 922

Research output: Contribution to journalArticle (Academic Journal)

Management of pituitary tumours

Lightman, SL., 2000, In : Prescribers' Journal. 40, p. 86 - 92 2.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Patient Progress - Stressed Out

Lightman, SL., 2000

Research output: Non-textual formPerformance

Significance of pulsatility in the HPA axis

Lightman, SL., Windle, RJ., Julian, MD., Harbuz, MS., Shanks, NM., Wood, SA., Kershaw, YM. & Ingram, CD., 2000, Mechanisms and biological significance of pulsatile hormone secretion. Chadwick, D. J. & Goode, J. A. (eds.). John Wiley & Sons, Inc, p. 244 - 260

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

65 Citations (Scopus)

Stress

Lightman, SL., 2000

Research output: Non-textual formPerformance

Stress busting

Lightman, SL., 2000

Research output: Non-textual formPerformance

The role of stressors and psychosocial variables in the stress process: A study of chronic caregiver stress

Vedhara, K., Shanks, NM., Anderson, S. & Lightman, SL., 2000, In : Psychosomatic Medicine. 62, p. 374 - 385

Research output: Contribution to journalArticle (Academic Journal)

65 Citations (Scopus)

Thyroid and sympathetic influences on leptin production in hypothyroidism and hyperthyroidism

Pinkney, JH., Goodrick, SW., Katz, J., Johnson, AB., Lightman, SL., Medbak, S., Coppack, SW. & Mohamed-Ali, V., 2000, In : International Journal of Obesity and Related Metabolic Disorders. 24, p. 1 - 2 (Suppl 1).

Research output: Contribution to journalArticle (Academic Journal)

Thyroid and sympathetic influences on leptin production in hypothyroidism and hyperthyroidism. 'Endocrinology of obesity: Basic, clinical and therapeutic aspects' Satellite symposium of 8th International Congress on Obesity, Venice 1998

Pinkney, JH., Goodrick, SW., Katz, J., Johnson, AB., Lightman, SL., Medbak, S., Coppack, SW. & Mohamed-Ali, V., 2000, International Journal of Obesity.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

1999

Activation of the hypothalamo-pituitary axis in adrenalectomized rats: potentiation by chronic stress

Marti, O., Harbuz, MS., Andres, R., Lightman, SL. & Armario, A., 1999, In : Brain Research. 821, p. 1 - 7

Research output: Contribution to journalArticle (Academic Journal)

Alterations in hypothalamic-pituitary-adrenal function correlated with the onset of murine SLE in MRL +/+ and lpr/lpr mice

Shanks, NM., Moore, PM., Perks, PA. & Lightman, SL., 1999, In : Brain, Behavior, and Immunity. 13, p. 348 - 360

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Assessing viral gene therapy in neuroendocrine models

Geddes, BJ., Harding, TC., Lightman, SL. & Uney, JB., 1999, In : Frontiers in Neuroendocrinology. 20, p. 296 - 316

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)

Assessing viral gene therapy in nneuroendocrine models

Geddes, BJ., Harding, TC., Lightman, SL. & Uney, JB., 1999, In : Frontiers in Neuroendocrinology. 20, p. 296 - 316

Research output: Contribution to journalArticle (Academic Journal)

Chronic stress in elderly carers of dementia patients is associated with increased vulnerability to infectious disease

Vedhara, K., Cox, NKN., Wilcock, GK., Perks, PA., Hunt, MA., Anderson, SJ., Lightman, SL. & Shanks, NM., 1999, In : Lancet. 353, p. 627 - 631

Research output: Contribution to journalArticle (Academic Journal)

365 Citations (Scopus)

Correlates and Predictors of Psychological and Physical Morbidity in Chronic Caregiver Stress

Vedhara, K., Shanks, NM., Lightman, SL. & Wilcock, GK., 1999, In : Psychological Medicine.

Research output: Contribution to journalArticle (Academic Journal)

Differential effects of psychological and immunological challenge on HPA axis function in adjuvant-induced arthritis

Harbuz, MS., Windle, RJ., Jessop, DS., Renshaw, D., Ingram, CD. & Lightman, SL., 1999, In : Annals of the New York Academy of Sciences. 876, p. 43 - 52

Research output: Contribution to journalArticle (Academic Journal)

Dynamic control of HPA function and its contribution to adaptive plasticity of the stress response

Lightman, SL., Windle, RJ., Ma, X-M., Harbuz, MS., Shanks, NM., Julian, MD., Wood, SA., Kershaw, YM. & Ingram, CD., 1999, Control Mechanisms of Stress and Emotion: Neuroendocrine-Based Studies. Yamashita, H., Funder, J. W., Verbalis, J. G., Ueta, Y. & Endo, Y. (eds.). Amsterdam:Elsevier, p. 111 - 125

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Effects of leptin on fasting-induced inhibition of neuronal nitric oxide synthase mRNA in the paraventricular and supraoptic nuclei of rats

Isse, T., Ueta, Y., Serino, R., Noguchi, J., Yamamoto, Y., Nomura, M., Shibuya, I., Lightman, SL. & Yamashita, H., 1999, In : Brain Research. 846, p. 229 - 235

Research output: Contribution to journalArticle (Academic Journal)

39 Citations (Scopus)

Fos mRNA expression in the forebrain of male and female Lewis rats following an acute immunological challenge

Julian, MD., Windle, RJ., Lightman, SL. & Ingram, CD., 1999, 29th Annual Meeting of Society for Neuroscience, USA. Vol. 25. p. 156 - 156 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

IgG response to influenza vaccination in elderly caregivers of dementia patients

Cox, N., Vedhara, K., Perks, PA., Lightman, SL. & Shanks, NM., 1999, British Society for Immunology, Harrogate. Immunology, Vol. 98 (Suppl). p. 158 - 158 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Insertion of an amino acid in the DNA-binding domain of the glucocorticoid receptor as a result of alternative splicing

Rivers, C. A., Levy, A., Hancock, J., Lightman, SL. & Norman, MR., 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 11, p. 4283 - 4286 4 p.

Research output: Contribution to journalArticle (Academic Journal)

105 Citations (Scopus)

LPS induced c-fos expression in the PVN and the A1/A2 brainstem noradrenergic cell groups is altered by adrenalectomy

Conde, GL., Chowdrey, H. S., Renshaw, D., Lightman, SL. & Harbuz, MS., 1999, In : Neuroendocrinology. 70, p. 175 - 185

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)
25 Citations (Scopus)

The hypothalamic-pituitary-adrenal axis response to endotoxin is attenuated during lactation

Shanks, NM., Windle, RJ., Perks, PA., Wood, SA., Ingram, CD. & Lightman, SL., 1999, In : Journal of Neuroendocrinology. 11, p. 857 - 865

Research output: Contribution to journalArticle (Academic Journal)

81 Citations (Scopus)

The 'Ology Hour - Physiology

Lightman, SL., 1999

Research output: Non-textual formPerformance

TV Interview on Stress for BBC TV

Lightman, SL., 1999

Research output: Non-textual formPerformance

Vasopressin and corticotropin-releasing hormone gene responses to novel stress in rats adapted to repeated restraint

Ma, X-M., Lightman, SL. & Aguilera, G., 1999, In : Endocrinology. 140, p. 3623 - 3632

Research output: Contribution to journalArticle (Academic Journal)

159 Citations (Scopus)
1998

Anterior pituitary cell population control: basal cell turnover and the effects of adrenalectomy and dexamethasone treatment

Nolan, LA., Kavanagh, E., Lightman, SL. & Levy, A., 1998, In : Journal of Neuroendocrinology. 10, p. 207 - 215

Research output: Contribution to journalArticle (Academic Journal)

101 Citations (Scopus)

Chronic stress in humans is associated with altered lymphocyte proliferation

Bauer, ME., Vedhara, K., Shanks, NM., Perks, PA., Tallon, D., Anderson, SJ., Wilcock, GK. & Lightman, SL., 1998, Unknown. Vol. 5. p. 5 - 5 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Differential effects of psychological and immunological challenge on HPA axis function in adjuvant-induced arthritis

Harbuz, MS., Windle, RJ., Jessop, DS., Renshaw, D., Ingram, CD. & Lightman, SL., 1998, Unknown. Vol. 16. p. 636 - 636 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Dynamic patterns of basal and stress-induced hypothalamo-pituitary-adrenal (HPA) activity in male and female Lewis rats

Julian, MD., Windle, RJ., Wood, SA., Kershaw, YM., Ingram, CD. & Lightman, SL., 1998, Unknown. Vol. 9.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Dynamics of the hypothalamo-pituitary-adrenal (HPA) axis during ageing in the rat

Julian, MD., Windle, RJ., Wood, SA., Kershaw, YM., Lightman, SL. & Ingram, CD., 1998, In : Folia Endocrinologica Japonica. 74 (2), p. 465 - 465 1 p.

Research output: Contribution to journalArticle (Academic Journal)

Hypothalamic plasticity in response to acute and chronic stress

Lightman, SL., Windle, RJ., Ma, XM., Harbuz, MS., Wood, SA., Kershaw, YM. & Ingram, CD., 1998, Unknown. p. 21 - 21 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Hypovolemia upregulates the expression of neuronal nitric oxide synthase gene in the paraventricular and supraoptic nuclei of rats

Ueta, Y., Levy, A., Lightman, SL., Hara, Y., Serino, R., Nomura, M., Shibuya, I., Hattori, Y. & Yamashita, H., 1998, In : Brain Research. 790, p. 25 - 32

Research output: Contribution to journalArticle (Academic Journal)

Inflammatory disease as chronic stress

Shanks, NM., Harbuz, MS., Jessop, DS., Perks, PA., Moore, PM. & Lightman, SL., 1998, Neuroimmunomodulation: Molecular aspects, integrative systems and clinical advances Vol. 840. M., S., L., C., G. & S. (eds.). New York Academy of Sciences, p. 599 - 607

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

44 Citations (Scopus)

Lactation: a physiological model of stress hyporesponsiveness of the neuroendocrine system

Lightman, SL., Windle, RJ., Da Costa, APC., Shanks, NM. & Ingram, CD., 1998, New Frontiers in Stress Research . Modulation of brain function. Levy, A., Grauer, E., Ben-Nathan, D. & de Kloet, ER. (eds.). Harwood Academic Publishers gmbh, The Netherlands, p. 59 - 71

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects

Pinkney, JH., Goodrick, S., Katz, JR., Johnson, AB., Lightman, SL., Coppack, SW., Yudkin, JS. & Mohamed-Ali, V., 1998, Unknown. p. 361 - 361 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

139 Citations (Scopus)

Long-term efects of neonatal exposure to endotoxin on the development of neuroendocrine-immune interactions

Shanks, NM., Perks, PA. & Lightman, SL., 1998, 5th Internet World Congress on Biomedical Sciences. Open for viewing Dec. 7-16, 1998.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Molecular biology of endocrine systems: Basic principles

Vallejo, M. & Lightman, SL., 1998, Clinical Endocrinology. Grossman, A. (ed.). Blackwell Scientific Publications, p. 3 - 23

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Neonatal handling and endotoxin exposure differentially alter neuroendocrine-immune interactions and adjuvant-induced arthritis

Shanks, NM., Perks, PA., Harbuz, MS., Jessop, DS. & Lightman, SL., 1998, Unknown. Vol. 5. p. 46 - 46 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Neuronal nitric oxide synthase gene expression in human pituitary tumours: a possible association with somatotroph adenomas and growth hormone-releasing hormone gene expression

Ueta, Y., Levy, A., Powell, M., Lightman, SL., Yoshimasa, K., Yokata, A. & Yamashita, H., 1998, In : Clinical Endocrinology. 49, 29-38-29-38.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)
1997

A central injection of interleukin-1b affects the expression of CRH, AVP, b-endorphin and ACTH in the rat spleen and thymus

Jessop, DS., Douthwaite, JA., Conde, GL., Lightman, SL. & Harbuz, MS., 1997, Proceedings of the Endocrine Society 79th Annual Congress: Minneapolis, Minnesota, USA. 11-14 June 1997. p. 283 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Effects of acute stress or centrally injected interleukin-1b on neuropeptide expression in the immune system

Jessop, DS., Douthwaite, JA., Conde, GL., Lightman, SL., Dayan, CM. & Harbuz, MS., 1997, In : Stress. 2, p. 133 - 144

Research output: Contribution to journalArticle (Academic Journal)

Effects of maternal iodine deficiency and thyroidectomy on basal neuroendocrine function in rat pups

Kondo, K., Levy, A. & Lightman, SL., 1997, In : Journal of Endocrinology. 152, p. 423 - 430

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)