1988 …2020

Research output per year

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Article (Academic Journal)
2020

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA.

Pooley, J., Rivers, C. A., Kilcooley, M., Paul, S. N., Cavga, A. D., Kershaw, Y. M., Muratcioglu, S., Gursoy, A., Keskin, O. & Lightman, S. L., 10 Jan 2020, In : PLoS ONE. 15, 1, 35 p., e0227520.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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53 Downloads (Pure)

Dynamic pituitary-adrenal interactions in the critically ill after cardiac surgery

Gibbison, B., Keenan, D. M., Roelfsema, F., Evans, J., Phillips, K., Rogers, C. A., Angelini, G. D. & Lightman, S. L., 1 May 2020, In : The Journal of clinical endocrinology and metabolism. 105, 5, dgz206.

Research output: Contribution to journalArticle (Academic Journal)

Involvement of CREB-regulated transcription coactivators (CRTC) in transcriptional activation of steroidogenic acute regulatory protein (Star) by ACTH

Smith, L. I. F., Victoria Huang, Mark Olah, Loc Trinh, Ying Liu, Hazell, G., Conway-Campbell, B., Zhao, Z., Antoine Martinez, Anne-Marie Lefrancois-Martinez, Lightman, S., Spiga, F. & Greti Aguilera, 1 Jan 2020, In : Molecular and Cellular Endocrinology. 499, 11 p., 110612.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
108 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
24 Downloads (Pure)

Research Priorities for the COVID-19 pandemic and beyond: A call to action for psychological science

Aggleton, J. P., Armitage, C. J., Chakrabarti, B., Cooper, C. L., Creswell, C., Dunsmuir, S., Fiske, S. T., Gathercole, S., Gough, B., Ireland, J. L., Jones, M. V., Jowett, A., Kagan, C., Karanika-Murray, M., Kaye, L., Kumari, V., Lewandowsky, S., Lightman, S. L., Malpass, D., Meins, E. & 9 others, Morgan, B. P., Morrison Coulthard, L., O’Connor, D. B., Reicher, S. D., Schacter, D. L., Sherman, S. M., Simms, V., Williams, A. & Wykes, T., 19 Jul 2020, In : British Journal of Psychology. p. 1-27 27 p., e12468.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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7 Downloads (Pure)

The Peacock study: feasibility of the dynamic characterisation of the paediatric hypothalamic-pituitary-adrenal function during and after cardiac surgery

Fudulu, D. P., Angelini, G. D., Papadopoulou, F. F., Evans, J., Walker-Smith, T. A. F., Kema, I., Van Fassen, M., Stoica, S., Caputo, M., Lightman, S. & Gibbison, B. J. J., 25 May 2020, In : BMC Cardiovascular Disorders. 20, 1, 8 p., 245 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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24 Downloads (Pure)
2019

Continuous Free Cortisol Profiles - Circadian Rhythms in Healthy Men

Bhake, R. C., Kluckner, V., Stassen, H., Russell, G. M., Leendertz, J., Stevens, K., Linthorst, A. C. E. & Lightman, S. L., Dec 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 5935-5947 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
17 Downloads (Pure)

Continuous Free Cortisol Profiles in Healthy Men - Validation of Microdialysis Method

Bhake, R., Russell, G. M., Kershaw, Y., Stevens, K., Zaccardi, F., Warburton, V. E. C., Linthorst, A. C. E. & Lightman, S. L., 16 Sep 2019, In : The Journal of clinical endocrinology and metabolism. dgz002.

Research output: Contribution to journalArticle (Academic Journal)

Dynamics of ACTH-Mediated Regulation of Gene Transcription in ATC1 and ATC7 Adrenal Zona Fasciculata Cell Lines

Hazell, G., Horn, G., Lightman, S. L. & Spiga, F., 15 Feb 2019, In : Endocrinology. 160, 3, p. 587-604 18 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
185 Downloads (Pure)

Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and cognitive capability at older ages: individual participant meta-analysis of five cohorts

Gardner, M., Lightman, S., Kuh, D., Comijs, H., Deeg, D., Gallacher, J., Geoffroy, M-C., Kivimaki, M., Kumari, M., Power, C., Hardy, R., Richards, M. & Ben-Shlomo, Y., 14 Mar 2019, In : Scientific Reports. 9, 1, 13 p., 4555.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
131 Downloads (Pure)

Glucocorticoid Receptor-Tethered Mineralocorticoid Receptors Increase Glucocorticoid-Induced Transcriptional Responses

Rivers, C. A., Rogers, M. F., Stubbs, F. E., Conway-Campbell, B. L., Lightman, S. L. & Pooley, J. R., 1 May 2019, In : Endocrinology. 160, 5, p. 1044-1056 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
173 Downloads (Pure)

Growth hormone secretion, fatigue and quality of life after childhood traumatic brain injury

Daskas, N., Sharples, P. M., Likeman, M., Lightman, S. L. & Crowne, E. C., Oct 2019, In : European Journal of Endocrinology. 181, 3, p. 331-338 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Improving glucocorticoid replacement profiles in adrenal insufficiency

Choudhury, S., Lightman, S. & Meeran, K., 6 May 2019, In : Clinical Endocrinology. 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
17 Downloads (Pure)

Role of the posterodorsal medial amygdala in predator odour stress‐induced puberty delay in female rats

Li, X. F., Adekunbi, D. A., Alobaid, H. M., Li, S., Pilot, M., Lightman, S. L. & O'Byrne, K. T., 1 Jun 2019, In : Journal of Neuroendocrinology. 31, 6, 12 p., e12719.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
162 Downloads (Pure)

Seasonal variation in antidepressant prescriptions, environmental light and web queries for seasonal affective disorder

Lansdall-Welfare, T., Lightman, S. & Cristianini, N., 1 Aug 2019, In : British Journal of Psychiatry. 215, 2, p. 481-484 4 p.

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

The Origin of GnRH Pulse Generation: An Integrative Mathematical-Experimental Approach

Voliotis, M., Li, X. F., De Burgh, R., Lass, G., Lightman, S. L., O'Byrne, K. T. & Tsaneva-Atanasova, K., 4 Dec 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 49, p. 9738-9747 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
30 Downloads (Pure)

Thirty years of neuroendocrinology: technological advances pave the way for molecular discovery

Stubbs, F., Conway-Campbell, B. & Lightman, S., 22 Mar 2019, In : Journal of Neuroendocrinology. 31, 3, 10 p., e12653.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
72 Downloads (Pure)

Utilization of the Allen Gene Expression Atlas to gain further insight into glucocorticoid physiology in the adult mouse brain

Kalafatakis, K., Giannakeas, N., Lightman, S., Charalampopoulos, I., Russell, G., Tsipouras, M. & Tzallas, A., 27 Jul 2019, In : Neuroscience Letters. 706, p. 194-200 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
40 Downloads (Pure)
2018

Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals

Turton, S., Myers, J. F. M., Mick, I., Colasanti, A., Venkataraman, A., Durant, C., Waldman, A., Brailsford, A., Parkin, M. C., Dawe, G., Rabiner, E. A., Gunn, R. N., Lightman, S. L., Nutt, D. J. & Lingford-Hughes, A., 25 Jun 2018, In : Molecular Psychiatry. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
207 Downloads (Pure)

Corticosteroids and other anti-Inflammatory strategies in pediatric heart surgery: a national survey of practice

Fudulu, D., Schadenberg, A. W. L., Gibbison, B., Jenkins, I. A., Lightman, S., Angelini, G. & Stoica, S., May 2018, In : World Journal for Pediatric and Congenital Heart Surgery. 9, 3, p. 289-293 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
295 Downloads (Pure)

Diurnal variations of psychometric indicators in Twitter content

Dzogang, F., Lightman, S. & Cristianini, N., 20 Jun 2018, In : PLoS ONE. 13, 6, 18 p., e019700.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
258 Downloads (Pure)

Kisspeptin neurones in the posterodorsal medial amygdala modulate sexual partner preference and anxiety in male mice

Adekunbi, D. A., Li, X. F., Lass, G., Shetty, K., Adegoke, O. A., Yeo, S. H., Colledge, W. H., Lightman, S. L. & O'Byrne, K. T., 1 Mar 2018, In : Journal of Neuroendocrinology. 30, 3, 9 p., e12572.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
223 Downloads (Pure)

Pulsatility of glucocorticoid hormones in pregnancy: Changes with gestation and obesity

Stirrat, L. I., Walker, J. J., Stryjakowska, K., Jones, N., Homer, N. Z. M., Andrew, R., Norman, J. E., Lightman, S. L. & Reynolds, R. M., 1 Apr 2018, In : Clinical Endocrinology. 88, 4, p. 592-600 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
10 Citations (Scopus)
204 Downloads (Pure)

SKOV3 cells containing a truncated ARID1a protein have a restricted genome-wide response to glucocorticoids

Stubbs, F. E., Birnie, M. T., Biddie, S. C., Lightman, S. L. & Conway-Campbell, B. L., 5 Feb 2018, In : Molecular and Cellular Endocrinology. 461, p. 226-235 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
250 Downloads (Pure)

Some distorted thoughts about ketamine as a psychedelic and a novel hypothesis based on NMDA receptor-mediated synaptic plasticity

Ingram, R., Kang, H. H., Lightman, S., Jane, D., Bortolotto, Z., Collingridge, G., Lodge, D. & Volianskis, A., 6 Jun 2018, In : Neuropharmacology.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
196 Downloads (Pure)

The emerging importance of ultradian glucocorticoid rhythms within metabolic pathology

Flynn, B. P., Conway-Campbell, B. L. & Lightman, S. L., 1 Jun 2018, In : Annales d'Endocrinologie. 79, 3, p. 112-114 3 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
229 Downloads (Pure)

Ultradian rhythmicity of plasma cortisol is necessary for normal emotional and cognitive responses in man

Kalafatakis, K., Russell, G. M., Harmer, C. J., Munafo, M. R., Marchant, N., Wilson, A., Brooks, J. C., Durant, C., Thakrar, J., Murphy, P., Thai, N. J. & Lightman, S. L., 24 Apr 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 17, p. E4091-E4100 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
23 Citations (Scopus)
373 Downloads (Pure)
2017

Circadian mood variations in Twitter content

Cristianini, N., Dzogang, F. & Lightman, S., 2017, In : Brain and Neuroscience Advances.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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247 Downloads (Pure)

Corticosteroids in septic shock: a systematic review and network meta-analysis

Gibbison, B., Lopez-Lopez, J. A., Higgins, J., Miller, T., Angelini, G., Lightman, S. & Annane, D., 28 Mar 2017, In : Critical Care. 21, 1, 3 p., 78.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
44 Citations (Scopus)
329 Downloads (Pure)

Dynamic responses of the adrenal steroidogenic regulatory network

Spiga, F., Zavala, E., Walker, J., Zhao, Z., Terry, J. & Lightman, S., 1 Aug 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 31, p. E6466-E6474 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
20 Citations (Scopus)
213 Downloads (Pure)

Dysfunctional Skin-Derived Glucocorticoid Synthesis Is a Pathogenic Mechanism of Psoriasis

Hannen, R., Udeh-Momoh, C., Upton, J., Wright, M., Michael, A., Gulati, A., Rajpopat, S., Clayton, N., Halsall, D., Burrin, J., Flower, R., Sevilla, L., Latorre, V., Frame, J., Lightman, S., Perez, P. & Philpott, M., 1 Aug 2017, In : Journal of Investigative Dermatology. p. 1630-1637 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
129 Downloads (Pure)

Genome-wide identification of basic helix-loop helix and NF-1 motifs underlying GR binding sites in male rat hippocampus

Pooley, J. R., Flynn, B. P., Grøntved, L., Baek, S., Guertin, M. J., Kershaw, Y. M., Birnie, M. T., Pellatt, A., Rivers, C. A., Schiltz, R. L., Hager, G. L., Lightman, S. L. & Conway-Campbell, B. L., 13 Feb 2017, In : Endocrinology. 158, 5, p. 1486–1501 27 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
10 Citations (Scopus)
234 Downloads (Pure)

Role of amygdala kisspeptin in pubertal timing in female rats

Adekunbi, D. A., Li, X. F., Li, S., Adegoke, O. A., Iranloye, B. O., Morakinyo, A. O., Lightman, S. L., Taylor, P. D., Poston, L. & O'Byrne, K. T., 28 Aug 2017, In : PLoS ONE. 12, 8, 15 p., e0183596.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
195 Downloads (Pure)

The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis

Freeman, D., Sheaves, B., Goodwin, G. M., Yu, L-M., Nickless, A., Harrison, P. J., Emsley, R., Luik, A. I., Foster, R. G., Wadekar, V., Hinds, C., Gumley, A., Jones, R., Lightman, S., Jones, S., Bentall, R., Kinderman, P., Rowse, G., Brugha, T., Blagrove, M. & 22 others, Gregory, A. M., Fleming, L., Walklet, E., Glazebrook, C., Davies, E. B., Hollis, C., Haddock, G., John, B., Coulson, M., Fowler, D., Pugh, K., Cape, J., Moseley, P., Brown, G., Hughes, C., Obonsawin, M., Coker, S., Watkins, E., Schwannauer, M., MacMahon, K., Siriwardena, A. N. & Espie, C. A., 1 Oct 2017, In : Lancet Psychiatry. 4, 10, p. 749-758 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
121 Citations (Scopus)
332 Downloads (Pure)

Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo

George, C. L., Birnie, M. T., Flynn, B., Kershaw, Y., Lightman, S. L. & Conway-Campbell, B. L., 5 Jan 2017, In : Molecular and Cellular Endocrinology. 439, p. 46-53 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
12 Citations (Scopus)
283 Downloads (Pure)
2016

A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system

Lopes, M. W., Leal, R. B., Guarnieri, R., Schwarzbold, M. L., Hoeller, A. A., Diaz, A. P., Boos, G., Lin, K., Linhares, M. N., Nunes, J. C., Quevedo, J., Bortolotto, Z. A., Markowitsch, H. J., Lightman, S. L. & Walz, R., Dec 2016, In : Translational Psychiatry. 6, 12, 9 p., e986.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
227 Downloads (Pure)

Cortisol and CBG: Getting cortisol to the right place at the right time

Henley, D., Lightman, S. & Carrell, R., Oct 2016, In : Pharmacology and Therapeutics. 166, p. 128-135 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
12 Citations (Scopus)
185 Downloads (Pure)

Effects of the pattern of glucocorticoid replacement on neural processing, emotional reactivity and well-being in healthy male individuals: study protocol for a randomised controlled trial

Kalafatakis, K. G., Russell, G. M., Harmer, C. J., Munafo, M. R., Marchant, N. J., Wilson, A., Brooks, J. C. W., Thai, N. J., Ferguson, S. G., Stevenson, K., Durant, C. F., Schmidt, K. & Lightman, S. L., 22 Jan 2016, In : Trials. 17, 1, 17 p., 44.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
343 Downloads (Pure)

Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light

Pilorz, V., Tam, SK., Hughes, S., Pothecary, CA., Jagannath, A., Hankins, MW., Bannerman, DM., Lightman, S., Vyazovskiy, VV., Nolan, PM., Foster, RG. & Pierson, SN., 8 Jun 2016, In : PLoS Biology. 14, 6, 24 p., e1002482.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
58 Citations (Scopus)
233 Downloads (Pure)
Open Access
File
21 Citations (Scopus)
293 Downloads (Pure)

The role of hippocampal NMDA receptors in long-term emotional responses following muscarinic receptor activation

Hoeller, A. A., Costa, A. P. R., Bicca, M. A., Matheus, F. C., Lach, G., Spiga, F., Lightman, S. L., Walz, R., Collingridge, G. L., Bortolotto, Z. A. & De Lima, T. C. M., 21 Jan 2016, In : PLoS ONE. 11, 1, 18 p., e0147293.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
240 Downloads (Pure)
2015

A simple complex case: Restoration of circadian cortisol activity

Bhake, R. & Lightman, S., 2015, In : AIMS Medical Science. 2, 3, p. 182-185

Research output: Contribution to journalArticle (Academic Journal)

Control of Body Weight by Eating Behavior in Children

Zandian, M., Bergh, C., Ioakimidis, I., Esfandiari, M., Shield, J., Lightman, S., Leon, M. & Södersten, P., 19 Oct 2015, In : Frontiers in Pediatrics. 3, 6 p., 89.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
261 Downloads (Pure)

Dynamic Pituitary-Adrenal Interactions in Response to Cardiac Surgery

Gibbison, B., Spiga, F., Walker, J. J., Russell, G. M., Zhao, Z., Stevenson, K., Henley, DE., Angelini, G. D. & Lightman, S. L., Apr 2015, In : Critical Care Medicine. 43, 4, p. 791-800 10 p.

Research output: Contribution to journalArticle (Academic Journal)

37 Citations (Scopus)

Heterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: results from a large patient cohort

Dénes, J., Swords, F., Rattenberry, E., Stals, K., Owens, M., Cranston, T., Xekouki, P., Moran, L., Kumar, A., Wassif, C., Fersht, N., Baldeweg, S. E., Morris, D., Lightman, S., Agha, A., Rees, A., Grieve, J., Powell, M., Boguszewski, C. L., Dutta, P. & 31 others, Thakker, R. V., Srirangalingam, U., Thompson, C. J., Druce, M., Higham, C., Davis, J., Eeles, R., Stevenson, M., O'Sullivan, B., Taniere, P., Skordilis, K., Gabrovska, P., Barlier, A., Webb, S. M., Aulinas, A., Drake, W. M., Bevan, J. S., Preda, C., Dalantaeva, N., Ribeiro-Oliveira, A., Garcia, I. T., Yordanova, G., Iotova, V., Evanson, J., Grossman, A. B., Trouillas, J., Ellard, S., Stratakis, C. A., Maher, E. R., Roncaroli, F. & Korbonits, M., Mar 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 3, p. E531-41

Research output: Contribution to journalArticle (Academic Journal)

Inactivation of corticotropin-releasing hormone-induced insulinotropic role by high-altitude hypoxia

Hao, K., Kong, F-P., Gao, Y-Q., Tang, J-W., Chen, J., Evans, A. M., Lightman, S. L., Chen, X-Q. & Du, J-Z., Mar 2015, In : Diabetes. 64, 3, p. 785-95 11 p.

Research output: Contribution to journalArticle (Academic Journal)

12 Citations (Scopus)

Rapid intra-adrenal feedback regulation of glucorticoid synthesis

Walker, J., Spiga, F., Gupta, R., Zhao, Z., Lightman, S. & Terry, J., 6 Jan 2015, In : Journal of the Royal Society Interface. 12, 102, p. 20140875 1 p.

Research output: Contribution to journalArticle (Academic Journal)

Relative Importance of the Arcuate and Anteroventral Periventricular Kisspeptin Neurons in Control of Puberty and Reproductive Function in Female Rats

Hu, M. H., Li, X. F., McCausland, B., Li, S. Y., Gresham, R., Kinsey-Jones, J. S., Gardiner, J. V., Sam, A. H., Bloom, S. R., Poston, L., Lightman, S. L., Murphy, K. G. & O'Byrne, K. T., Jul 2015, In : Endocrinology. 156, 7, p. 2619-31 13 p.

Research output: Contribution to journalArticle (Academic Journal)

27 Citations (Scopus)

Reversible biological adaptations in obesity

Södersten, P., Bergh, C., Shield, J. & Lightman, S., May 2015, In : Lancet Diabetes and Endocrinology. 3, 5, p. 314

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)
42 Citations (Scopus)