Research output per year
Research output per year
PhD, diploma
BS8 1TD
Each year, as many people die of fungal infections as of tuberculosis or malaria. Individuals at risk of contracting fungal infections include patients suffering from HIV/AIDS, undergoing cancer chemotherapy or organ transplantations and low-birthweight infants. Incidence rates of fungal infections are on the rise and so are the economic costs associated with life-threatening fungal infections due to the need for extended hospitalisations.
To mitigate the impact of fungal infections on human health and life, it is imperative to understand how fungi cause disease in humans. This will allow us identify suitable drug targets to effectively treat fungal infections. At Bristol's School of Cellular and Molecular Medicine, we aim to understand how heat shock protein Hsp90, a regulator of the cell’s protein homeostasis, regulates fungal virulence and evolution. We employ a two-pronged approach by combining research into the basic biology of Hsp90 in fungi with targeted quests for novel drug targets as currently available antifungal therapies are either ineffective or riddled by the emergence of antifungal drug resistance.
Duke University
2002 → 2009
Humboldt-Universität zu Berlin
1997 → 2002
Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Research output: Contribution to journal › Article (Academic Journal) › peer-review
Research output: Contribution to journal › Article (Academic Journal) › peer-review
Diezmann, S. (Contributor), University of Bristol, 1 Jan 2019
DOI: 10.3410/f.736330300.793563564, https://doi.org/10.3410%2Ff.736330300.793563564
Dataset
Stephanie Diezmann (Advisor)
Activity: Membership types › Membership or peer review panel or committee
Stephanie Diezmann (Participant)
Activity: Participating in or organising an event types › Participation in conference
Stephanie Diezmann (Editor)
Activity: Publication peer-review and editorial work types › Editorial activity