Projects per year
Personal profile
Research interests
Biology computes... from individual cells deciding how to differentiate during development, to social insects coordinating their actions when scavenging for food; the ability to perform complex computations and process information enables life.
I head up the Biocompute Lab at the University of Bristol, which explores the molecular-scale mechanisms that individual cells and groups of cells use to make sense of their world. We apply tools and methods from the field of synthetic biology to create new living systems from the ground-up. By studying these artificial systems using novel techniques we are developing based on sequencing, microfluidics and computational modelling, we aim to better understand the rules governing how biological parts are best pieced together to perform useful computations. Understanding the computational architecture of cells opens new ways of reprogramming them to tackle problems spanning the sustainable production of materials to novel therapeutics. It also provides key insights into how biology controls the complex processes and structures sustaining life.
External positions
Postdoctoral Associate, MIT, Massachusetts Institute of Technology (MIT)
Apr 2014 → Dec 2015Marie Curie Fellow/Associate Scientist, DSM
Apr 2012 → Apr 2014Fingerprint Dive into the research topics where Thomas E Gorochowski is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
Next-generation agent-based modelling framework for multicellular design
1/06/18 → 31/03/21
Project: Research
Research Output
An Engineering Theory of Evolution
Grierson, C. S., Castle, S. D. & Gorochowski, T. E., 26 Aug 2020, Preprints.org.Research output: Contribution to specialist publication › Article (Specialist Publication)
Cheetah: a computational toolkit for cybergenetic control
Gorochowski, T. E., Pedone, E., De Cesare, I., Zamora, C., Haener, D., Marucci, L., Postiglione, L., Shannon, B. M., Grierson, C. S., Savery, N. J. & Di Bernardo, M., 5 Aug 2020, bioRxiv.Research output: Contribution to specialist publication › Article (Specialist Publication)
Precision design of stable genetic circuits carried in highly‐insulated E. coli genomic landing pads
Park, Y., Espah Borujeni, A., Gorochowski, T. E., Shin, J. & Voigt, C. A., 19 Aug 2020, In : Molecular Systems Biology. 16, 8, e9584.Research output: Contribution to journal › Article (Academic Journal)
Open Access