Dr Tom M Palmer

Search results

• 2022

  A review of group-based methods for teaching statistics in higher education

  Jones, E. M. & Palmer, T. M., 1 Mar 2022, In: Teaching Mathematics and Its Application. 41, 1, p. 69-86 18 p., hrab002.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Higher Education 100%
  • Teaching Statistics 93%
  • Collaborative Learning 75%
  • statistics 44%
  • Review 43%
  16 Downloads (Pure)

• Effectiveness of BNT162b2 booster doses in England: an observational study in OpenSAFELY-TPP

  Hulme, W. J., Williamson, E. J., Horne, E., Green, A. CA., Nab, L., Keogh, R., Parker, E. PK., Walker, V. M., Palmer, T. M., Curtis, H. J., Wiedemann, M., Cunningham, C., Walker, A. J., Fisher, L., MacKenna, B., Rentsch, C. T., Schultze, A., Bhaskaran, K., Tazare, J., Tomlinson, L. A. & 24 others, McDonald, H. I., Morton, C. E., Croker, R., Andrews, C. D., Hopcroft, L. EM., Park, R. Y., Massey, J., Mehrkar, A., Morley, J., Bacon, S. CJ., Evans, D., Inglesby, P., Hickman, G., Davy, S., Dillingham, I., Ward, T., Mahalingasivam, V., Zheng, B., Douglas, I. J., Evans, S. JW., Bates, C., Sterne, J. AC., Hernan, M. A. & Goldacre, B., 6 Jun 2022, (E-pub ahead of print) (medRxiv).

  Research output: Working paper › Preprint

  • England 100%
  • Observational Studies 78%
  • SARS Virus 45%
  • National Institutes of Health (U.S.) 40%
  • Organized Financing 27%

• Effects of general and central adiposity on circulating lipoprotein, lipid, and metabolite levels in UK Biobank: A multivariable Mendelian randomization study

  Bell, J. A., Richardson, T. G., Wang, Q., Sanderson, E. C. M., Palmer, T. M., Walker, V. M., O'Keefe, L. M., Timpson, N. J., Cichonska, A., Julkunen, H., Wurtz, P., Holmes, M. V. & Davey Smith, G., 6 Jul 2022, In: The Lancet Regional Health - Europe. 21, 100457.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Waist-Hip Ratio 100%
  • Adiposity 90%
  • Random Allocation 84%
  • Lipoproteins 81%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 58%
  5 Downloads (Pure)

• Mendelian randomization

  Sanderson, E., Glymour, M. M., Holmes, M. V., Kang, H., Morrison, J., Munafò, M. R., Palmer, T., Schooling, C. M., Wallace, C., Zhao, Q. & Davey Smith, G., 10 Feb 2022, (E-pub ahead of print) In: Nature Reviews Methods Primers. 2, 1, 6.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • epidemiological studies 100%
  • triangulation 91%
  • Law 44%
  • evidence 35%
  14 Downloads (Pure)

• Sensitivity to missing not at random dropout in clinical trials: Use and interpretation of the trimmed means estimator

  Hazewinkel, A-D., Bowden, J., Wade, K. H., Palmer, T., Wiles, N. J. & Tilling, K., 15 Apr 2022, In: Statistics in Medicine. 41, 8, p. 1462-1481 20 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Trimmed Mean 100%
  • Drop out 96%
  • Missing at Random 90%
  • Clinical Trials 69%
  • Interpretation 51%
  37 Downloads (Pure)

• The consultation open and close study: A feasibility study of a complex intervention

  Murphy, C., Scott, A. P., Salisbury, C., Walter, S. R. & Palmer, T. M., 14 Apr 2022, (E-pub ahead of print) In: NIHR Open Research. p. 1 -58 58 p.

  Research output: Contribution to journal › Article (Academic Journal)

  Open Access

  File

  • Feasibility Studies 100%
  • Referral and Consultation 70%
  • General Practice 47%
  • Telephone 46%
  • General Practitioners 44%

• Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: Findings from a Mendelian randomisation study

  Hamilton, F. W., Thomas, M., Arnold, D. T., Palmer, T. M., Moran, E., Mentzer, A. J., Maskell, N. A., Baillie, J. K., Summers, C., Hingorani, A. D., MacGowan, A. P., Khandaker, G. M., Mitchell, R. E., Davey Smith, G., Ghazal, P. & Timpson, N. J., 15 Jul 2022, (E-pub ahead of print) p. 2022.07.14.22277638, (medRxiv).

  Research output: Working paper › Preprint

  • Random Allocation 100%
  • Sepsis 82%
  • National Institutes of Health (U.S.) 46%
  • Interleukin-6 Receptors 33%
  • Genome-Wide Association Study 33%

• Treatment group outcome variance difference after dropout as an indicator of missing-not-at-random bias in randomized clinical trials

  Hazewinkel, A-D., Tilling, K., Wade, K. H. & Palmer, T., 18 Apr 2022, (E-pub ahead of print) p. 2022.04.15.22273918, (medRxiv).

  Research output: Working paper › Preprint

  • Randomized Controlled Trials 100%
  • Epidemiology 43%
  • Research Ethics Committees 39%
  • Biomedical Research 37%
  • Epidemiologic Effect Modifiers 27%

• Waning effectiveness of BNT162b2 and ChAdOx1 COVID-19 vaccines over six months since second dose: a cohort study using linked electronic health records

  Horne, E. MF., Hulme, W. J., Keogh, R. H., Palmer, T. M., Williamson, E. J., Parker, E. PK., Green, A., Walker, V., Walker, A. J., Curtis, H., Fisher, L., MacKenna, B., Croker, R., Hopcroft, L., Park, R. Y., Massey, J., Morely, J., Mehrkar, A., Bacon, S., Evans, D. & 9 others, Inglesby, P., Morton, C. E., Hickman, G., Davy, S., Ward, T., Dillingham, I., Goldacre, B., Hernan, M. A. & Sterne, J. AC., 1 Jan 2022, p. 2022.03.23.22272804, (medRxiv).

  Research output: Working paper › Preprint

  • Electronic Health Records 100%
  • Vaccines 73%
  • Cohort Studies 66%
  • National Institutes of Health (U.S.) 41%
  • SARS Virus 32%
• 2021

  Changes in presentations with features potentially indicating cancer in primary care during the COVID-19 pandemic: a retrospective cohort study

  Scott, L. J., Murphy, C., Price, S., Horwood, J. P., Denholm, R. E., Lewis, R., Palmer, T. M. & Salisbury, C., 24 May 2021, In: BMJ Open. 11, 5, 11 p., e050131.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • insulin receptor-related receptor 100%
  • Pandemics 95%
  • Primary Health Care 70%
  • Cohort Studies 61%
  • Retrospective Studies 60%
  1 Citation (Scopus)

  22 Downloads (Pure)

• Sex differences in the risk of coronary heart disease associated with type 2 diabetes: a Mendelian Randomization analysis

  Peters, T., Holmes, M. V., Richards, B., Palmer, T. M., Forgetta, V., Lindgren, C. M., Asselbergs, F. W., Nelson, C. P., Samani, N. J., McCarthy, M. I., Mahajan, A., Davey Smith, G., Woodward, M., O'Keeffe, L. M. & Peters, S. A., Feb 2021, In: Diabetes Care. 44, 2, p. 556-562 7 p., dc201137.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Mendelian Randomization Analysis 100%
  • Sex Characteristics 58%
  • Coronary Disease 54%
  • Type 2 Diabetes Mellitus 46%
  • Random Allocation 27%
  4 Citations (Scopus)

  25 Downloads (Pure)

• Software aplpication profile: Bayesian estimation of inverse variance weighted and MR-Egger models for two-sample Mendelian randomization studies - mrbayes

  Uche-Ikonne, O., Dondelinger, F. & Palmer, T., 1 Feb 2021, In: International Journal of Epidemiology. 50, 1, p. 43-49

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

• The role of combinatorial health technologies in supporting older people with long-term conditions: Responsibilisation or co-management of healthcare?

  Varey, S. E., Dixon, M., Hernandez, A., Mateus, C., Palmer, T. M. & Milligan, C., 1 Jan 2021, In: Social Science and Medicine. 269, 11 p., 113545.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • co-management 100%
  • Biomedical Technology 94%
  • Older People 91%
  • Healthcare 57%
  • Health 48%
  11 Downloads (Pure)

• To Adjust or Not to Adjust? When a "Confounder" Is Only Measured After Exposure

  Groenwold, R. H. H., Palmer, T. M. & Tilling, K. M., 1 Mar 2021, In: Epidemiology. 32, 2, p. 194-201 8 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Observational Studies 100%
  • Blood Pressure 81%
  • Literacy 76%
  • Neuroticism 75%
  • Pupil 69%
  6 Citations (Scopus)

  17 Downloads (Pure)
• 2020

  Assessment of a causal relationship between body mass index and atopic dermatitis

  Budu-Aggrey, A., Watkins, S. H., Brumpton, B. M., Løset, M., Tyrrell, J., Modalsli, E. H., Vie, G. Å., Palmer, T., Fritsche, L. G., Nielsen, J. B., Romundstad, P. R., Davey Smith, G., Åsvold, B. O., Paternoster, L. & Brown, S. J., 17 Apr 2020, (E-pub ahead of print) In: Journal of Allergy and Clinical Immunology. 147, 1, p. 400-403 3 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Atopic Dermatitis 100%
  • Body Mass Index 68%
  36 Downloads (Pure)

• Collider bias undermines our understanding of COVID-19 disease risk and severity

  Griffith, G. J., Morris, T. T., Tudball, M. J., Herbert, A., Mancano, G., Pike, L., Sharp, G. C., Sterne, J., Palmer, T. M., Davey Smith, G., Tilling, K., Zuccolo, L., Davies, N. M. & Hemani, G., 12 Nov 2020, In: Nature Communications. 11, 12 p., 5749 (2020).

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • infectious diseases 100%
  • SARS Virus 87%
  • Behavioral Genetics 84%
  • Infections 56%
  • Datasets 47%
  168 Citations (Scopus)

  200 Downloads (Pure)

• Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

  Richardson, T. G., Sanderson, E., Palmer, T. M., Ala-Korpela, M., Ference, B. A., Davey Smith, G. & Holmes, M. V., 23 Mar 2020, In: PLoS Medicine. 17, 3, p. e1003062

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Mendelian Randomization Analysis 100%
  • Apolipoproteins 73%
  • Lipoproteins 58%
  • Coronary Disease 54%
  • Apolipoproteins B 48%
  99 Citations (Scopus)

• Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

  Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T. S., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B. E., Chen, Y., Matic, L. & 63 others, Gale, J. D., Lee, J., Zhang, W., Quazi, A., Ala-Korpela, M., Choi, S. H., Claringbould, A., Danesh, J., Davey Smith, G., de Masi, F., Elmståhl, S., Engström, G., Fauman, E., Fernandez, C., Franke, L., Franks, P. W., Giedraitis, V., Haley, C., Hamsten, A., Ingason, A., Johansson, Å., Joshi, P. K., Lind, L., Lindgren, C. M., Lubitz, S., Palmer, T., Macdonald-Dunlop, E., Magnusson, M., Melander, O., Michaelsson, K., Morris, A. P., Mägi, R., Nagle, M. W., Nilsson, P. M., Nilsson, J., Orho-Melander, M., Polasek, O., Prins, B., Pålsson, E., Qi, T., Sjögren, M., Sundström, J., Surendran, P., Võsa, U., Werge, T., Wernersson, R., Westra, H-J., Yang, J., Zhernakova, A., Ärnlöv, J., Fu, J., Smith, J. G., Esko, T., Hayward, C., Gyllensten, U., Landen, M., Siegbahn, A., Wilson, J. F., Wallentin, L., Butterworth, A. S., Holmes, M. V., Ingelsson, E. & Mälarstig, A., 16 Oct 2020, In: Nature Metabolism. 2, p. 1135–1148 (2020) 15 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Drug Evaluation 100%
  • Proteins 29%
  • Quantitative Trait Loci 25%
  • Interleukin-16 15%
  • Chemokine Receptors 11%
  41 Citations (Scopus)

  36 Downloads (Pure)

• The MRC IEU OpenGWAS data infrastructure

  Elsworth, B., Lyon, M., Alexander, T., Liu, Y., Matthews, P., Hallett, J., Bates, P., Palmer, T., Haberland, V., Smith, G. D., Zheng, J., Haycock, P., Gaunt, T. R. & Hemani, G., 10 Aug 2020, In: bioRxiv.

  Research output: Contribution to journal › Article (Academic Journal)

  • genome-wide association study 100%
  • infrastructure 94%
  • metadata 64%
  • Python 61%
  • imports 41%
• 2019

  A Mendelian Randomization dictionary: Useful definitions and descriptions for undertaking, understanding and interpreting Mendelian Randomization studies

  Lawlor, D. A., Wade, K. H., Borges, M. C., Palmer, T., Hartwig, F. P., Hemani, G. & Bowden, J., 5 Feb 2019, OSF Preprints.

  Research output: Working paper

  • Dictionary Definitions 100%
  • Randomization 84%
  • Dictionary 30%
  • Web Sites 17%
  • Online Discussion 12%

• Apolipoprotein B underlies the causal relationship of circulating blood lipids with coronary heart disease

  Richardson, T. G., Sanderson, E., Palmer, T. M., Ala-Korpela, M., Ference, B. A., Davey Smith, G. & Holmes, M. V., 29 Aug 2019, In: medRxiv.

  Research output: Contribution to journal › Article (Academic Journal)

  Open Access

  File

  • Apolipoproteins B 100%
  • Coronary Disease 79%
  • Lipids 58%
  • LDL Cholesterol 58%
  • Apolipoprotein A-I 44%
  40 Downloads (Pure)

• Associations of mortality with own blood pressure using son's blood pressure as an instrumental variable

  Carslake, D., Fraser, A., May, M., Palmer, T., Silventoinen, K., Tynelius, P., Lawlor, D. & Smith, G. D., 20 Jun 2019, In: Scientific Reports. 9, 1, 12 p., 8986.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Nuclear Family 100%
  • Blood Pressure 59%
  • Mortality 46%
  • Cardiovascular Diseases 11%
  • Causality 7%
  202 Downloads (Pure)

• Conditioning on a mediator

  Groenwold, R., Palmer, T. & Tilling, K. M., 23 Dec 2019, OSF Preprints.

  Research output: Working paper

• Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

  Budu-Aggrey, A., Brumpton, B., Tyrrell, J., Watkins, S., Modalsli, E. H., Celis-Morales, C., Ferguson, L. D., Vie, G. Å., Palmer, T., Fritsche, L. G., Løset, M., Nielsen, J. B., Zhou, W., Tsoi, L. C., Wood, A. R., Jones, S. E., Beaumont, R., Saunes, M., Romundstad, P. R., Siebert, S. & 8 others, McInnes, I. B., Elder, J. T., Davey Smith, G., Frayling, T. M., Åsvold, B. O., Brown, S. J., Sattar, N. & Paternoster, L., Jan 2019, In: PLoS Medicine. 19, 1, p. 71-86 18 p., e1002739.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Psoriasis 100%
  • Random Allocation 99%
  • Body Mass Index 72%
  • Mendelian Randomization Analysis 20%
  • Skin Diseases 12%
  72 Citations (Scopus)

  247 Downloads (Pure)
• 2018

  Attachment and therapeutic alliance in psychological therapy for people with recent onset psychosis who use cannabis

  Berry, K., Palmer, T., Gregg, L., Barrowclough, C. & Lobban, F., 1 May 2018, In: Clinical Psychology and Psychotherapy. 25, 3, p. 440-445 6 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Therapeutic Alliance 100%
  • psychosis 85%
  • Cannabis 78%
  • Psychotic Disorders 69%
  • Psychology 50%
  9 Citations (Scopus)

• How effective and cost effective are innovative combinatorial technologies and practices for supporting older people with long-term conditions to remain well in the community?

  Varey, S. E., Hernandez Huerta, M. A., Palmer, T. M., Mateus, C., Wilkinson, J., Dixon, M. P. & Milligan, C., 28 Feb 2018, In: BMJ Open. 8, 2

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Program Evaluation 100%
  • Technology 87%
  • Costs and Cost Analysis 82%
  • Health 65%
  • Biomedical Technology 56%

• Instrumental variable methods for a binary outcome were used to informatively address noncompliance in a randomized trial in surgery

  Cook, J. A., MacLennan, G. S., Palmer, T., Lois, N. & Emsley, R., 1 Apr 2018, In: Journal of Clinical Epidemiology. 96, p. 126-132 7 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  • Retinal Perforations 100%
  • Uncertainty 37%
  • Clinical Protocols 20%
  • Random Allocation 19%
  • Intention 18%
  4 Citations (Scopus)

• Lancashire and Cumbria Innovation Alliance Test Bed: Final Evaluation Report for a Targeted Supported Self-Care Programme

  Milligan, C., Mateus, C., Palmer, T., Varey, S., Hernandez Huerta, A. & Dixon, M., 30 Jun 2018, Lancaster University: Lancaster University.

  Research output: Book/Report › Authored book

• Older people with long term conditions using technologies supporting home based care

  Mateus, C., Hernandez, A., Palmer, T., Varey, S. & Milligan, C., Oct 2018, In: Value in Health. 21, Suppl. 3, p. S220-S220

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

• Reading comprehension difficulties in children with rolandic epilepsy

  Currie, N. K., Lew, A. R., Palmer, T. M., Basu, H., De Goede, C., Iyer, A. & Cain, K., 1 Mar 2018, In: Developmental Medicine and Child Neurology. 60, 3, p. 275-282 8 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  • Rolandic Epilepsy 100%
  • Reading 56%
  • Child 28%
  13 Citations (Scopus)

• Software Application Profile: mrrobust - a tool for performing two-sample summary Mendelian randomization analyses

  Spiller, W., Davies, N. & Palmer, T. M., 12 Sep 2018, (E-pub ahead of print) In: International Journal of Epidemiology. 7 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Mendelian Randomization Analysis 100%
  • Software 46%
  • Genome-Wide Association Study 32%
  • Epidemiology 24%
  • Statistics 24%
  52 Citations (Scopus)

  298 Downloads (Pure)

• UK families with children with rare chromosome disorders: Changing experiences of diagnosis and counselling (2003-2013)

  Szczepura, A., Wynn, S., Searle, B., Khan, A. J., Palmer, T., Biggerstaff, D., Elliott, J. & Hultén, M. A., 1 May 2018, In: Clinical Genetics. 93, 5, p. 972-981 10 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Chromosome Disorders 100%
  • Counseling 58%
  • Self-Help Groups 32%
  • Child 29%
  • Referral and Consultation 20%
  2 Citations (Scopus)
• 2017

  Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis

  Dale, C. E., Fatemifar, G., Palmer, T. M., White, J., Prieto-Merino, D., Zabaneh, D., Engmann, J. E. L., Shah, T., Wong, A., Warren, H. R., McLachlan, S., Trompet, S., Moldovan, M., Morris, R. W., Sofat, R., Kumari, M., Hyppönen, E., Jefferis, B. J., Gaunt, T., Ben-Shlomo, Y. & 25 others, Zhou, A., Gentry-Maharaj, A., Ryan, A., UCLEB Consortium, METASTROKE consortium, de Mutsert, R., Noordam, R., Caulfield, M. J., Jukema, J. W., Worrall, B., Munroe, P. B., Menon, U., Power, C., Kuh, D. J. L., Lawlor, D. A., Humphries, S. E., Mook-Kanamori, D. O., Davey Smith, G., Sattar, N., Kivimaki, M. J., Price, J. F., Dudridge, F., Hingorani, A., Holmes, M. V. & Cass, J. P., 13 Jun 2017, In: Circulation. 135, 24, p. 2373-2388 16 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Mendelian Randomization Analysis 100%
  • Body Fat Distribution 83%
  • Waist-Hip Ratio 72%
  • Adiposity 64%
  • Coronary Disease 54%
  174 Citations (Scopus)

  377 Downloads (Pure)

• Correcting the Standard Errors of 2-Stage Residual Inclusion Estimators for Mendelian Randomization Studies

  Palmer, T. M., Holmes, M. V., Keating, B. J. & Sheehan, N. A., 1 Nov 2017, In: American Journal of Epidemiology. 186, 9, p. 1104-1114 11 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  • Random Allocation 100%
  • Research Personnel 71%
  • Least-Squares Analysis 37%
  • Genotype 24%
  5 Citations (Scopus)

• Education and coronary heart disease: mendelian randomisation study

  Tillmann, T., Vaucher, J., Okbay, A., Pikhart, H., Peasey, A., Kubinova, R., Pajak, A., Tamosiunas, A., Malyutina, S., Hartwig, F. P., Fischer, K., Veronesi, G., Palmer, T., Bowden, J., Davey Smith, G., Bobak, M. & Holmes, M. V., 30 Aug 2017, In: BMJ. 358, 10 p., j3542.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Random Allocation 100%
  • Coronary Disease 90%
  • Education 64%
  • Genetic Predisposition to Disease 38%
  • Odds Ratio 24%
  76 Citations (Scopus)

  225 Downloads (Pure)

• Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis

  Roetker, N. S., Armasu, S. M., Pankow, J. S., Lutsey, P. L., Tang, W., Rosenberg, M. A., Palmer, T. M., MacLehose, R. F., Heckbert, S. R., Cushman, M., de Andrade, M. & Folsom, A. R., 1 Jul 2017, In: Journal of Thrombosis and Haemostasis. 15, 7, p. 1334-1343 10 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Mendelian Randomization Analysis 100%
  • Venous Thromboembolism 67%
  • Meta-Analysis 46%
  • Random Allocation 12%
  • Odds Ratio 11%
  9 Citations (Scopus)

• Using genetic variation to explore the causal effect of maternal pregnancy adiposity on future offspring adiposity: a Mendelian randomization study

  Richmond, R., Timpson, N., Felix, J. F., Palmer, T. M., Gaillard, R., McMahon, G., Davey Smith, G., Jaddoe, V. W. V. & Lawlor, D., 24 Jan 2017, In: PLoS Medicine. 14, 1, 17 p., e1002221.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Adiposity 100%
  • Random Allocation 93%
  • Genetic Variation 92%
  • Body Mass Index 68%
  • Mothers 60%
  47 Citations (Scopus)

  377 Downloads (Pure)
• 2016

  Antipsychotic prescribing in care homes before and after launch of a national dementia strategy: an observational study in English institutions over a 4-year period

  Szczepura, A., Wild, D., Khan, A. J., Owen, D. W., Palmer, T., Muhammad, T., Clark, M. D. & Bowman, C., 20 Sep 2016, In: BMJ Open. 6, 9, p. e009882

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  • Home Care Services 100%
  • Antipsychotic Agents 86%
  • Dementia 79%
  • Observational Studies 73%
  • Long-Term Care 38%
  30 Citations (Scopus)

• Erratum: Genetic evidence for causal relationships between maternal obesity-related traits and birth weight (JAMA (2016) 315:11 (1129-1140) 10.1001/JAMA.2016.1975))

  Tyrrell, J., Richmond, R. C. & Palmer, T. M., 19 Apr 2016, In: JAMA - Journal of the American Medical Association. 315, 15, 1 p.

  Research output: Contribution to journal › Comment/debate (Academic Journal) › peer-review

• Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

  Tyrrell, J., Richmond, R. C., Palmer, T. M., Feenstra, B., Rangarajan, J., Metrusky, S., Cavadino, A., Paternoster, L., Armstrong, L. L., De Silva, N. M. G., Wood, A. R., Horikoshi, M., Geller, F., Myhre, R., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Painter, J. N., Hottenga, J. J., Allard, C. & 44 others, Berry, D. J., Bouchard, L., Das, S., Evans, D. M., Hakonarson, H., Hayes, M. G., Heikkinen, J., Hofman, A., Knight, B. A., Lind, P. A., McCarthy, M. I., McMahon, G., Medland, S. E., Melbye, M., Morris, A. P., Nodzenski, M., Reichetzeder, C., Ring, S. M., Sebed, S., Sengpiel, V., Sorensen, T. I. A., Willemsen, G., de Geus, E. J. C., Martin, N. G., Spector, T. D., Power, C., Järvelin, M-R., Bisgaard, H., Grant, S. F. A., Nohr, E. A., Jaddoe, VW., Jacobsson, B., Murray, J. C., Hocher, B., Hattersley, A. T., Scholtens, D. M., Davey Smith, G., Hivert, M-F., Felix, J. F., Hyppönen, E., Lowe, W. L., Frayling, T. M., Lawlor, D. A. & Freathy, R. M., 15 Mar 2016, In: JAMA - Journal of the American Medical Association. 315, 11, p. 1129-1140 12 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Maternal Obesity 100%
  • Birth Weight 69%
  • Blood Pressure 43%
  • Mothers 35%
  • Body Mass Index 32%
  142 Citations (Scopus)

  410 Downloads (Pure)

• Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk

  Tragante, V., Asselbergs, F. W., Swerdlow, D. I., Palmer, T. M., Moore, J. H., de Bakker, P. I. W., Keating, B. J. & Holmes, M. V., 1 May 2016, In: Human Genetics. 135, 5, p. 453-467 15 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  • oxidized low density lipoprotein 100%
  • Coronary Disease 88%
  • Lipids 65%
  • Coronary Artery Disease 44%
  • LDL Cholesterol 32%
  9 Citations (Scopus)

• Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

  Rodriguez, S., Gaunt, T. R., Guo, Y., Zheng, J., Barnes, M. R., Tang, W., Danish, F., Johnson, A., Castillo, B. A., Li, Y. R., Hakonarson, H., Buxbaum, S. G., Palmer, T., Tsai, M. Y., Lange, L. A., Ebrahim, S., Davey Smith, G., Lawlor, D. A., Folsom, A. R., Hoogeveen, R. & 3 others, Reiner, A., Keating, B. & Day, I. N., Jan 2016, In: European Journal of Human Genetics. 24, 1, p. 106-112 7 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Gallbladder Diseases 100%
  • Single Nucleotide Polymorphism 60%
  • Obesity 50%
  • Lipids 47%
  • Genes 29%
  20 Citations (Scopus)

  451 Downloads (Pure)

• Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

  White, J., Sofat, R., Hemani, G., Shah, T., Engmann, J., Dale, C., Shah, S., Kruger, F. A., Giambartolomei, C., Swerdlow, D. I., Palmer, T., McLachlan, S., Langenberg, C., Zabaneh, D., Lovering, R., Cavadino, A., Jefferis, B., Finan, C., Wong, A., Amuzu, A. & 31 others, Ong, K., Gaunt, T. R., Warren, H., Davies, T-L., Drenos, F., Cooper, J., Ebrahim, S., Lawlor, D. A., Talmud, P. J., Humphries, S. E., Power, C., Hypponen, E., Richards, M., Hardy, R., Kuh, D., Wareham, N., Ben-Shlomo, Y., Day, I. N., Whincup, P., Morris, R., Strachan, M. W. J., Price, J., Kumari, M., Kivimaki, M., Plagnol, V., Whittaker, J. C., Smith, G. D., Dudbridge, F., Casas, J. P., Holmes, M. V. & UCLEB (University College London-London School of Hygiene & Tropical Medicine-Edinburgh-Bristol Consortium, Apr 2016, In: Lancet Diabetes and Endocrinology. 4, 4, p. 327-336 10 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Mendelian Randomization Analysis 100%
  • Uric Acid 63%
  • Coronary Disease 54%
  • Single Nucleotide Polymorphism 15%
  • Random Allocation 12%
  74 Citations (Scopus)

  224 Downloads (Pure)
• 2015

  Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

  Nüesch, E., Dale, C., Palmer, T. M., White, J., Keating, B. J., van Iperen, E. P., Goel, A., Padmanabhan, S., Asselbergs, F. W., Verschuren, W. M., Wijmenga, C., Van der Schouw, Y. T., Onland-Moret, N. C., Lange, L. A., Hovingh, G. K., Sivapalaratnam, S., Morris, R. W., Whincup, P. H., Wannamethe, G. S., Gaunt, T. R. & 24 others, Ebrahim, S., Steel, L., Nair, N., Reiner, A. P., Kooperberg, C., Bolton, J. L., McLachlan, S., Price, J. F., Strachan, M. W., Robertson, C. M., Kleber, M. E., Delgado, G., Ben-Shlomo, Y., Lawlor, D. A., Cooper, J., Davies, T. L., Drenos, F., Kivimaki, M., Shah, S., Warren, H., Wong, A., Davey Smith, G., Leon, D. A. & EPIC-Netherland Investigators, 15 May 2015, In: International Journal of Epidemiology.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Mendelian Randomization Analysis 100%
  • Coronary Disease 54%
  • Meta-Analysis 46%
  • Stroke 42%
  • Blood Pressure 23%
  61 Citations (Scopus)

• A Mendelian randomization study of circulating uric acid and type 2 diabetes

  Sluijs, I., Holmes, M. V., van der Schouw, Y. T., Beulens, J. W. J., Asselbergs, F. W., Huerta, J. M., Palmer, T. M., Arriola, L., Balkau, B., Barricarte, A., Boeing, H., Clavel-Chapelon, F., Fagherazzi, G., Franks, P. W., Gavrila, D., Kaaks, R., Khaw, K. T., Kühn, T., Molina-Montes, E., Mortensen, L. M. & 23 others, Nilsson, P. M., Overvad, K., Palli, D., Panico, S., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sala, N., Schmidt, J. A., Scott, R. A., Sieri, S., Slimani, N., Spijkerman, A. M., Tjonneland, A., Travis Dphil, R. C., Tumino, R., van der A, D. L., Sharp, S. J., Forouhi, N. G., Langenberg, C., Riboli, E., Wareham, N. J. & consortium, I., Aug 2015, In: Diabetes. 64, 8, p. 3028-3036 9 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Uric Acid 100%
  • Random Allocation 96%
  • Type 2 Diabetes Mellitus 73%
  • Risk Adjustment 14%
  • Datasets 8%
  72 Citations (Scopus)

• Effect of smoking on physical and cognitive capability in later life: a multicohort study using observational and genetic approaches

  North, T-L., Palmer, T. M., Lewis, S. J., Cooper, R., Power, C., Pattie, A., Starr, J. M., Deary, I. J., Martin, R. M., Aihie Sayer, A., Kumari, M., Cooper, C., Kivimaki, M., Kuh, D., Ben-Shlomo, Y. & Day, I. N. M., 2015, In: BMJ Open. 5, 12, p. e008393

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Observational Studies 100%
  • Smoking 93%
  • Smokers 90%
  • Random Allocation 83%
  • Ex-Smokers 83%
  24 Citations (Scopus)

• Estimating Structural Mean Models with Multiple Instrumental Variables using the Generalised Method of Moments

  Clarke, P. S., Palmer, T. M. & Windmeijer, F., 2015, In: Statistical Science. 30, 1, p. 96-117 22 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Instrumental Variables 100%
  • Generalized Method of Moments 81%
  • Hypertension 19%
  • Model 18%
  • Multiplicative 15%
  9 Citations (Scopus)

  33 Downloads (Pure)

• Fitting fixed-and random-effects meta-analysis models using structural equation modeling with the sem and gsem commands

  Palmer, T. M. & Sterne, J. A. C., 1 Jan 2015, In: Stata Journal. 15, 3, p. 645-671 27 p., st0398.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Structural Equation Modeling 100%
  • Model Analysis 89%
  • Fixed Effects 84%
  • Random Effects 73%
  • Framework 41%
  3 Citations (Scopus)

• Improving health outcomes for young people with long term conditions

  Griffiths, F. E., Atherton, H., Barker, J. R., Cave, J. AK., Dennick, K., Dowdall, P., Fraser, J., Huxley, C., Kim, S-W., Madan, J. J., Matharu, H., Musumadi, L., Palmer, T. M., Paul, M., Sankaranarayanan, S., Slowther, A-M., Sujan, M. A., Sutcliffe, P. A. & Sturt, J., 1 Jan 2015, In: Digital Health. 1

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Communication 100%
  • Health 64%
  • Social Media 27%
  • Patient Care Team 26%
  • Patient Participation 25%

• Systematic review and metaanalysis of genetic association studies of urinary symptoms and prolapse in women

  Cartwright, R., Kirby, A. C., Tikkinen, K. A. O., Mangera, A., Thiagamoorthy, G., Rajan, P., Pesonen, J., Ambrose, C., Gonzalez-Maffe, J., Bennett, P., Palmer, T., Walley, A., Järvelin, M. R., Chapple, C. & Khullar, V., 1 Feb 2015, In: American Journal of Obstetrics and Gynecology. 212, 2, p. 199.e1-199.e24

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  • Prolapse 100%
  • Genetic Association Studies 93%
  • Overactive Urinary Bladder 82%
  • Systematic Reviews 64%
  • Lower Urinary Tract Symptoms 53%
  55 Citations (Scopus)