1992 …2020

Research output per year

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Personal profile

Research interests

Understanding the mechanisms underlying basic functions of the brain, such as synaptic transmission and plasticity. These represent fundamental functions and abilities of the brain that affect its output activities. These also forms the molecular basis of the brain activity which are involved in neurological conditions affecting learning and memory and/or implicated in Alzheimer's disease and epilepsy. We are investigating the roles different receptor systems in the control of synaptic plasticity and epileptiform activity in the hippocampus.

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Research Output

  • 55 Article (Academic Journal)
  • 3 Review article (Academic Journal)
  • 1 Chapter in a book
  • 1 Letter (Academic Journal)

(2S,6S)- and (2R,6R)- hydroxynorketamine inhibit the induction of NMDA receptor-dependent LTP at hippocampal CA1 synapses in mice

Kang, H. H., Park, P., Han, M., Tidball, P. J., Bortolotto, Z. A., Lodge, D. & Kaang, B-K., 20 Aug 2020, (Accepted/In press) In : Brain and Neuroscience Advances.

Research output: Contribution to journalArticle (Academic Journal)

  • Differential sensitivity of three forms of hippocampal synaptic potentiation to depotentiation

    Park, P., Sanderson, T. M., Bortolotto, Z. A., Georgiou, J., Zhuo, M., Kaang, B. K. & Collingridge, G. L., 3 Apr 2019, In : Molecular Brain. 12, 1, 5 p., 30.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
  • 2 Citations (Scopus)
    124 Downloads (Pure)

    Hippocampus-dependent fear conditioning is not sensitized by muscarinic receptor activation following systemic injection of pilocarpine

    Hoeller, A. A., Lach, G., Costa, A. P. R., Walz, R., Bortolotto, Z. A. & De Lima, T. C. M., 1 Dec 2019, In : Neurology Psychiatry and Brain Research. 34, p. 44-49 6 p.

    Research output: Contribution to journalArticle (Academic Journal)

  • Supervised Work

    Functional study of Kainate receptors in the mossy fibre pathway in the hippocampus

    Author: Lee, Y., 28 Nov 2019

    Supervisor: Bortolotto, Z. (Supervisor) & Collingridge, G. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)


    Modulation of alternative splicing regulators during epithelial-mesenchymal transition in cancer progression

    Author: Li, L., 24 Mar 2020

    Supervisor: Gaston, K. (Supervisor), Oltean, S. (Supervisor) & Bortolotto, Z. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)