Adapting high throughput technologies to understand the process of viral zoonosis

Matthews, David A (Principal Investigator)

School of Cellular and Molecular Medicine

Status	Finished
Effective start/end date	4/01/16 → 3/01/20
Links	http://gtr.rcuk.ac.uk/projects?ref=BB/M02542X/1

Structured keywords

UNCOVER
Bristol BioDesign Institute
BrisSynBio
Covid19

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Project entry on Gateway to Research

14 Article (Academic Journal)

Direct RNA sequencing of Respiratory Syncytial Virus infected human cells generates a detailed overview of RSV polycistronic mRNA and transcript abundance.
Donovan-Banfield, IA., Milligan, R., Hall, S., Gao, T., Murphy, E. M. R., Li, J. B., Shalwi, G., Hiscox, J., Zhuang, X., McKeating, J., Fearns, R. & Matthews, D. A., 10 Nov 2022, In: PLoS ONE. 17, 11, p. 1-20 e0276697.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

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2 Downloads (Pure)
Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein
Davidson, A. D., Kavanagh Williamson, M., Lewis, S. D., Shoemark, D. K., Carroll, M. W., Heesom, K. J., Zambon, M., Ellis, J., Lewis, P. A., Hiscox, J. A. & Matthews, D. A., 28 Jul 2020, In: Genome Medicine. 12, 15 p., 68.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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196 Citations (Scopus)

135 Downloads (Pure)
Deep splicing plasticity of the human adenovirus type 5 transcriptome drives virus evolution
Donovan-Banfield, IA., Turnell, A. S., Hiscox, J. A., Leppard, K. N. & Matthews, D. A., 13 Mar 2020, In: Communications Biology. 3, 14 p., 124 (2020).
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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25 Citations (Scopus)

94 Downloads (Pure)