Adapting high throughput technologies to understand the process of viral zoonosis

2022

Direct RNA sequencing of Respiratory Syncytial Virus infected human cells generates a detailed overview of RSV polycistronic mRNA and transcript abundance.

Donovan-Banfield, IA., Milligan, R., Hall, S., Gao, T., Murphy, E. M. R., Li, J. B., Shalwi, G., Hiscox, J., Zhuang, X., McKeating, J., Fearns, R. & Matthews, D. A., 10 Nov 2022, In: PLoS ONE. 17, 11, p. 1-20 e0276697.

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2020

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

Davidson, A. D., Kavanagh Williamson, M., Lewis, S. D., Shoemark, D. K., Carroll, M. W., Heesom, K. J., Zambon, M., Ellis, J., Lewis, P. A., Hiscox, J. A. & Matthews, D. A., 28 Jul 2020, In: Genome Medicine. 12, 15 p., 68.

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206 Citations (Scopus)

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Deep splicing plasticity of the human adenovirus type 5 transcriptome drives virus evolution

Donovan-Banfield, IA., Turnell, A. S., Hiscox, J. A., Leppard, K. N. & Matthews, D. A., 13 Mar 2020, In: Communications Biology. 3, 14 p., 124 (2020).

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25 Citations (Scopus)

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Neuropilin-1 is a host factor for SARS-CoV-2 infection

Daly, J., Simonetti, B., Klein, K., Kavanagh Williamson, M., Anton Plagaro, C., Shoemark, D. K., Sessions, R. B., Matthews, D. A., Davidson, A. D., Cullen, P. J. & Yamauchi, Y., 13 Nov 2020, In: Science. 370, 6518, p. 861-865 5 p., eabd3072.

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695 Citations (Scopus)

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2019

High Resolution Analysis of Respiratory Syncytial Virus Infection In Vivo

Aljabr, W., Armstrong, S., Rickett, N. Y., Pollakis, G., Touzelet, O., Cloutman-Green, E., Matthews, D. A. & Hiscox, J. A., 10 Oct 2019, In: Viruses. 11, 10, 16 p., 926.

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5 Citations (Scopus)

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2018

High throughput discovery of protein variants using proteomics informed by transcriptomics

Matthews, D., Bessant, C. & Saha, S., 30 Apr 2018, (E-pub ahead of print) In: Nucleic Acids Research.

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4 Citations (Scopus)

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PITDB: a database of translated genomic elements

Saha, S., Chatzimichali, E. A., Matthews, D. A. & Bessant, C., 4 Jan 2018, In: Nucleic Acids Research. 46, D1, p. D1223-D1228 6 p., gkx906.

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Zika virus infection preferentially counterbalances human peripheral monocyte and/or NK cell activity

Lum, F. M., Lee, D., Chua, T. K., Tan, J. J. L., Lee, C. Y. P., Liu, X., Fang, Y., Lee, B., Yee, W. X., Rickett, N. Y., Chia, P. Y., Lim, V., Leo, Y. S., Matthews, D. A., Hiscox, J. A. & Nga, L. F. P., 28 Mar 2018, In: mSphere. 3, 2, e00120-18.

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23 Citations (Scopus)

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2017

Comparison of protein expression during wild-type, and E1B-55k-deletion, adenovirus infection using quantitative time-course proteomics

Fu, Y. R., Turnell, A. S., Davis, S., Heesom, K. J., Evans, V. C. & Matthews, D. A., 20 Jun 2017, In: Journal of General Virology. 98, 6, p. 1377-1388 12 p.

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9 Citations (Scopus)

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Deep sequencing of RNA from blood and oral swab samples reveals the presence of nucleic acid from a number of pathogens in patients with acute Ebola virus disease and is consistent with bacterial translocation across the gut

Carroll, M. W., Haldenby, S., Rickett, N. Y., Pályi, B., Garcia-Dorival, I., Liu, X., Barker, G., Bore, J. A., Koundouno, F. R., Williamson, E. D., Laws, T. R., Kerber, R., Sissoko, D., Magyar, N., Di Caro, A., Biava, M., Fletcher, T. E., Sprecher, A., Ng, L. F. P., Rénia, L., & 6 othersMagassouba, N., Günther, S., Wölfel, R., Stoecker, K., Matthews, D. A. & Hiscox, J. A., 23 Aug 2017, In: mSphere. 2, 4, 19 p., e00325-17.

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Proteomics Informed by Transcriptomics for Characterising Active Transposable Elements and Genome Annotation in Aedes Aegypti

Maringer, K., Yousuf, A., Heesom, K., Fan, J., Lee, D., Fernandez-Sesma, A., Bessant, C., Matthews, D. & Davidson, A., 19 Jan 2017, In: BMC Genomics. 18, 18 p., 101.

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33 Citations (Scopus)

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Proteomics informed by transcriptomics for characterising differential cellular susceptibility to Nelson Bay orthoreovirus infection

Mok, L., Wynne, J. W., Tachedjian, M., Shiell, B. J., Ford, K., Matthews, D., Bacic, A. & Michalski, W. P., 14 Aug 2017, In: BMC Genomics. 18, 615, 17 p.

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4 Citations (Scopus)

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Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

Liu, X., Matthews, D., Connor, J. H., Carroll, M. W. & Hiscox, J. A., 19 Jan 2017, In: Genome Biology. 18, 17 p., 4.

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Virus genomes reveal factors that spread and sustained the Ebola epidemic

Dudas, G. & et al., 20 Apr 2017, In: Nature. 544, 7650, p. 309-315 7 p.

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Adapting high throughput technologies to understand the process of viral zoonosis

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