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Analysing the cell biology of Parkinson's Disease-linked missense mutation in the retromer VPS35 subunit.

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  1. 2018
  2. Published

    Structural insights into the architecture and membrane interactions of the conserved COMMD proteins

    Healy, M. D., Hospenthal, M. K., Hall, R. J., Chandra, M., Chilton, M., Tillu, V., Chen, K. E., Celligoi, D. J., McDonald, F. J., Cullen, P. J., Lott, J. S., Collins, B. M. & Ghai, R., 13 Aug 2018, In : eLife. 7, 29 p., e35898.

    Research output: Contribution to journalArticle

  3. 2017
  4. Published

    The emerging role of retromer in neuroprotection

    McMillan, K. J., Korswagen, H. C. & Cullen, P. J., Aug 2017, In : Current Opinion in Cell Biology. 47, p. 72-82 11 p.

    Research output: Contribution to journalArticle

  5. 2016
  6. Published

    Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins

    McMillan, K. J., Gallon, M. J., Jellett, A. P., Clairfeuille, T., Tilley, F. C., McGough, I., Danson, C. M., Heesom, K. J., Wilkinson, K. A., Collins, B. M. & Cullen, P. J., 15 Aug 2016, In : Journal of Cell Biology. 214, 4, p. 389-399 11 p.

    Research output: Contribution to journalArticle

  7. 2015
  8. Published

    Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes

    Wang, W., Wang, X., Fujioka, H., Hoppel, C., Whone, A. L., Caldwell, M. A., Cullen, P. J., Liu, J. & Zhu, X., 30 Nov 2015, In : Nature Medicine.

    Research output: Contribution to journalArticle

  9. Published

    A defect in the retromer accessory protein, SNX27, manifests by infantile myoclonic epilepsy and neurodegeneration

    Damseh, N., Danson, C. M., Al-Ashhab, M., Abu-Libdeh, B., Gallon, M., Sharma, K., Yaacov, B., Caldwell, M. A., Edvardson, S., Cullen, P. J., Elpeleg, O. & Coulthard, E., Jul 2015, In : neurogenetics. 16, 3, p. 215-21 7 p.

    Research output: Contribution to journalArticle

  10. 2014
  11. Published

    Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation

    McGough, I. J., Steinberg, F., Jia, D., Barbuti, P. A., McMillan, K. J., Heesom, K. J., Whone, A. L., Caldwell, M. A., Billadeau, D. D., Rosen, M. K. & Cullen, P. J., 21 Jul 2014, In : Current Biology. 24, 14, p. 1670-1676 7 p.

    Research output: Contribution to journalArticle

  12. Published

    Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation: Erratum

    McGough, I. J., Steinberg, F., Jia, D., Barbuti, P. A., McMillan, K. J., Heesom, K. J., Whone, A. L., Caldwell, M. A., Billadeau, D. D., Rosen, M. K. & Cullen, P. J., 21 Jul 2014, In : Current Biology. 24, 14, p. 1678 1 p.

    Research output: Contribution to journalArticle

  13. Published

    Retromer: A Master Conductor of Endosome Sorting

    Burd, C. & Cullen, P. J., Feb 2014, In : Cold Spring Harbor Perspectives in Biology. 6, 2, 13 p., 016774.

    Research output: Contribution to journalArticle