Anti-angiogenic compounds based on modulation of VEGF splicing

Oltean, Sebastian (Principal Investigator)

Status	Finished
Effective start/end date	1/10/16 → 1/02/17
Links	http://gtr.rcuk.ac.uk/projects?ref=BB/P012035/1

Research Groups and Themes

Academic Respiratory Unit

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Project entry on Gateway to Research

6 Article (Academic Journal)
1 Editorial (Academic Journal)
1 Review article (Academic Journal)

The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor
Legge, D. N., Moriarty, W. F., Lee, D. A., Szemes, M., Zahed, A., Panousopoulos, L., Chung, W. Y., Aghabi, Y., Barratt, J., Williams, R., Pritchard-Jones, K., Malik, K. T. A., Oltean, S. & Brown, K. W., 28 Sept 2021, In: Molecular Oncology. 18 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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5 Citations (Scopus)

191 Downloads (Pure)
The natural drug DIAVIT is protective in a type II mouse model of diabetic nephropathy
Stevens, M., Neal, C. R., Craciun, E. C., Dronca, M., Harper, S. J. & Oltean, S., 13 Mar 2019, In: PLOS ONE. 14, 3, 20 p., e0212910.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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9 Citations (Scopus)

321 Downloads (Pure)
The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo
Stevens, M., Star, E., Lee, M., Innes, E., Li, L., Bowler, E., Harper, S., Bates, D. O. & Oltean, S., 21 Aug 2019, In: RNA Biology. 16, 12, p. 1672-1681 11 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
File
7 Citations (Scopus)

202 Downloads (Pure)