CENTRE FOR CASUAL ANALYSES IN TRANSLATIONAL EPIDEMIOLOGY (CAiTE)

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2018

Maternal thyroid function and child educational attainment: Prospective cohort study

Nelson, S. M., Haig, C., McConnachie, A., Sattar, N., Ring, S. M., Davey Smith, G., Lawlor, D. A. & Lindsay, R. S., 20 Feb 2018, In : BMJ. 360, 8 p., 84.

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15 Citations (Scopus)
266 Downloads (Pure)
2017

Age at menarche and lung function: a Mendelian randomization study

Gill, D., Sheehan, N., Wielscher, M., Nick, S., Amaral, A., Thompson, J., Granell, R., Leynaert, B., Gómez Real, F., Hall, I., Tobin, M., Auvinen, J., Ring, S., Jarvelin, M-R., Wain, L. V., Henderson, J., Jarvis, D. & Minelli, C., 17 Jun 2017, In : European Journal of Epidemiology. 10 p.

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14 Citations (Scopus)
832 Downloads (Pure)

Body mass index trajectories from 2 to 18 years – exploring differences between European cohorts

Graversen, L., Howe, L. D., Sorensen, T., Sovio, U., Hohwü, L., Tilling, K. M., Laitinen, J., Taanila, A., Pouta, A., Järvelin, M. R. & Obel, C., Apr 2017, In : Pediatric Obesity. 12, 2, p. 102-109 8 p.

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3 Citations (Scopus)
252 Downloads (Pure)

Programming of Adiposity in Childhood and Adolescence: Associations With Birth Weight and Cord Blood Adipokines

Simpson, J., Smith, A. D. A. C., Fraser, A., Sattar, N., Lindsay, R. S., Ring, S. M., Tilling, K., Davey Smith, G., Lawlor, D. A. & Nelson, S. M., 1 Feb 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 2, p. 499-506 8 p.

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23 Citations (Scopus)
401 Downloads (Pure)

The epigenetic clock and physical development during childhood and adolescence: longitudinal analysis from a UK birth cohort

Simpkin, A., Howe, L., Tilling, K., Gaunt, T., Lyttleton, O., McArdle, W., Ring, S., Horvath, S., Davey Smith, G. & Relton, C., Apr 2017, In : International Journal of Epidemiology. 46, 2, p. 549-558 10 p.

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31 Citations (Scopus)
221 Downloads (Pure)
2016

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: genetic variants as instruments for circulating levels.

Bonilla, C., Lewis, S., Rowlands, M-A., Gaunt, T., Davey Smith, G., Gunnell, D., Palmer, T., Donovan, J., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A. & 22 others, Schleutker, J., Nordestgaard, B. G., Travis, R. C., Pashayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., The PRACTICAL, C., Lathrop, M., Martin, R. & Holly, J., 1 Oct 2016, In : International Journal of Cancer. 139, 7, p. 1520-1533 14 p.

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9 Citations (Scopus)
398 Downloads (Pure)

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence

Wang, Q., Würtz, P., Auro, K., Morin-Papunen, L., Kangas, A. J., Soininen, P., Tiainen, M., Tynkkynen, T., Joensuu, A., Havulinna, A. S., Aalto, K., Salmi, M., Blankenberg, S., Zeller, T., Viikari, J., Kähönen, M., Lehtimäki, T., Salomaa, V., Jalkanen, S., Järvelin, M-R. & 5 others, Perola, M., Raitakari, O. T., Lawlor, D. A., Kettunen, J. & Ala-Korpela, M., Oct 2016, In : International Journal of Epidemiology. 45, 5, p. 1445-1457 13 p.

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22 Citations (Scopus)
385 Downloads (Pure)

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

Rodriguez, S., Gaunt, T. R., Guo, Y., Zheng, J., Barnes, M. R., Tang, W., Danish, F., Johnson, A., Castillo, B. A., Li, Y. R., Hakonarson, H., Buxbaum, S. G., Palmer, T., Tsai, M. Y., Lange, L. A., Ebrahim, S., Davey Smith, G., Lawlor, D. A., Folsom, A. R., Hoogeveen, R. & 3 others, Reiner, A., Keating, B. & Day, I. N., Jan 2016, In : European Journal of Human Genetics. 24, 1, p. 106-112 7 p.

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15 Citations (Scopus)
401 Downloads (Pure)

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H. & 31 others, Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A-P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J-J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Kurki, M. I., Kals, M., Stergiakouli, E., Smith, G. D. & International Headache Genetics Consortium, Aug 2016, In : Nature Genetics. 48, 8, p. 856-66 11 p.

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203 Citations (Scopus)
100 Downloads (Pure)

Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies

Simpkin, A. J., Hemani, G., Suderman, M., Gaunt, T. R., Lyttleton, O., McArdle, W. L., Ring, S. M., Sharp, G. C., Tilling, K., Horvath, S., Kunze, S., Peters, A., Waldenberger, M., Ward-Caviness, C., Nohr, E. A., Sorensen, T., Relton, C. L. & Smith, G. D., 1 Jan 2016, In : Human Molecular Genetics. 25, 1, p. 191-201 11 p.

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74 Citations (Scopus)
265 Downloads (Pure)

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

Bonilla, C., Lewis, S. J., Martin, R. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, B. G., Travis, R. C., Pashayan, N. & 17 others, Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Lathrop, M., Davey Smith, G. & the PRACTICAL Consortium, 4 Apr 2016, In : BMC Medicine. 14, 1, 66.

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20 Citations (Scopus)
249 Downloads (Pure)

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K., Shah, S. & 31 others, Kleber, M. E., Guo, X., Lyytikäinen, L-P., Fava, C., Eriksson, N., Nolte, I. M., Magnusson, P. K., Salfati, E. L., Rallidis, L. S., Theusch, E., Smith, A. J. P., Folkersen, L., Witkowska, K., Pers, T. H., Joehanes, R., Drenos, F., Eicher, J. D., Evans, A., Hunt, S. C., Kim, Y. K., Kivimaki, M., Kuh, D., Lin, L., Tobin, M. D., Wain, L. V., Wilson, J. F., Cooper, R. S., Wong, A., Kumari, M., Palmer, C. N. A. & CHARGE-EchoGen Consortium, Oct 2016, In : Nature Genetics. 48, 10, p. 1171-1184 14 p.

Research output: Contribution to journalArticle (Academic Journal)

180 Citations (Scopus)

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 190 others, Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Havulinna, A. S., Zhang, H., Donnelly, L. A., Groves, C. J., Rayner, N. W., Neville, M. J., Robertson, N. R., Yiorkas, A. M., Herzig, K. H., Kajantie, E., Zhang, W., Willems, S. M., Lannfelt, L., Malerba, G., Soranzo, N., Trabetti, E., Verweij, N., Evangelou, E., Moayyeri, A., Vergnaud, A. C., Nelson, C. P., Poveda, A., Varga, T. V., Caslake, M., De Craen, A. J. M., Trompet, S., Luan, JA., Scott, R. A., Harris, S. E., Liewald, D. C. M., Marioni, R., Menni, C., Farmaki, A. E., Hallmans, G., Renström, F., Huffman, J. E., Hassinen, M., Burgess, S., Vasan, R. S., Felix, J. F., Uria-Nickelsen, M., Malarstig, A., Reilly, D. F., Hoek, M., Vogt, T. F., Lin, H., Lieb, W., Traylor, M., Markus, H. S., Highland, H. M., Justice, A. E., Marouli, E., Lindström, J., Uusitupa, M., Komulainen, P., Lakka, T. A., Rauramaa, R., Polasek, O., Rudan, I., Rolandsson, O., Franks, P. W., Dedoussis, G., Spector, T. D., Jousilahti, P., Männistö, S., Deary, I. J., Starr, J. M., Langenberg, C., Wareham, N. J., Brown, M. J., Dominiczak, A. F., Connell, J. M., Jukema, J. W., Sattar, N., Ford, I., Packard, C. J., Esko, T., Mägi, R., Metspalu, A., De Boer, R. A., Van Der Meer, P., Van Der Harst, P., Gambaro, G., Ingelsson, E., Lind, L., De Bakker, P. I. W., Numans, M. E., Brandslund, I., Christensen, C., Petersen, E. R. B., Korpi-Hyövälti, E., Oksa, H., Chambers, J. C., Kooner, J. S., Blakemore, A. I. F., Franks, S., Jarvelin, M. R., Husemoen, L. L., Linneberg, A., Skaaby, T., Thuesen, B., Karpe, F., Tuomilehto, J., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., Holmen, O. L., Hveem, K., Willer, C. J., Tuomi, T., Groop, L., Käräjämäki, A., Palotie, A., Ripatti, S., Salomaa, V., Alam, D. S., Majumder, A. A. S., Di Angelantonio, E., Chowdhury, R., McCarthy, M. I., Poulter, N., Stanton, A. V., Sever, P., Amouyel, P., Arveiler, D., Blankenberg, S., Ferrières, J., Kee, F., Kuulasmaa, K., Müller-Nurasyid, M., Veronesi, G., Virtamo, J., Deloukas, P., Elliott, P., Zeggini, E., Kathiresan, S., Melander, O., Kuusisto, J., Laakso, M., Padmanabhan, S., Porteous, D. J., Hayward, C., Scotland, G., Collins, F. S., Mohlke, K. L., Hansen, T., Pedersen, O., Boehnke, M., Stringham, H. M., Frossard, P., Newton-Cheh, C., Tobin, M. D., Nordestgaard, B. G., Caulfield, M. J., Mahajan, A., Morris, A. P., Tomaszewski, M., Samani, N. J., Saleheen, D., Asselbergs, F. W., Lindgren, C. M., Danesh, J., Wain, L. V., Butterworth, A. S., Howson, J. M. M. & Munroe, P. B., Oct 2016, In : Nature Genetics. 48, 10, p. 1151-1161 11 p.

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127 Citations (Scopus)
437 Downloads (Pure)
2015

A genome-wide association study of body mass index across early life and childhood

Warrington, N. M., Howe, L. D., Paternoster, L., Kaakinen, M., Herrala, S., Huikari, V., Wu, Y. Y., Kemp, J. P., Timpson, N. J., Pourcain, B. S., Davey Smith, G., Tilling, K., Jarvelin, M-R., Pennell, C. E., Evans, D. M., Lawlor, D. A., Briollais, L. & Palmer, L. J., 7 May 2015, In : International Journal of Epidemiology. 44, 2, p. 700-712 12 p.

Research output: Contribution to journalArticle (Academic Journal)

61 Citations (Scopus)

Commentary: an even clearer portrait of bias in observational studies?

Davies, N. M., Jul 2015, In : Epidemiology. 26, 4, p. 505-8 4 p.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium

Linneberg, A., Jacobsen, R. K., Skaaby, T., Taylor, A. E., Fluharty, M. E., Jeppesen, J. L., Bjorngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R. E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T. S., Wannamethee, S. G., Lahti, J., Raikkonen, K. & 40 others, Palotie, A., Wong, A., Dalgård, C., Ford, I., Ben-Shlomo, Y., Christiansen, L., Kyvik, K. O., Kuh, D. J. L., Eriksson, J. G., Whincup, P. H., Mbarek, H., De Geus, E. J. C., Vink, J. M., Boomsma, D. I., Smith, G. D., Lawlor, D. A., Kisialiou, A., McConnachie, A., Padmanabhan, S., Jukema, J. W., Power, C., Hypponen, E., Preisig, M., Waeber, G., Vollenweider, P., Korhonen, T., Laatikainen, T., Salomaa, V., Kaprio, J., Kivimaki, M. J., Smith, B. H., Hayward, C., Sorensen, T., Thuesen, B. H., Sattar, N., Morris, R. W., Romundstad, P. R., Munafò, M. R., Jarvelin, M. R. & Husemoen, L. L. N., 1 Dec 2015, In : Circulation: Cardiovascular Genetics. 8, 6, p. 832-841 10 p.

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42 Citations (Scopus)
388 Downloads (Pure)

Estimating Structural Mean Models with Multiple Instrumental Variables using the Generalised Method of Moments

Clarke, P. S., Palmer, T. M. & Windmeijer, F., 2015, In : Statistical Science. 30, 1, p. 96-117 22 p.

Research output: Contribution to journalArticle (Academic Journal)

8 Citations (Scopus)
33 Downloads (Pure)

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sorensen, T., Munafò, M. R. & Sattar, N., 11 Aug 2015, In : BMJ Open. 5, 8, 12 p., e008808.

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26 Citations (Scopus)
370 Downloads (Pure)

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight evidence from genetic analysis and randomised trials

Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J. & 113 others, Howard, P., Cooper, J. A., Drenos, F., Li, Y. R., Lowe, G., Gallacher, J., Stewart, M. C. W., Tzoulaki, I., Buxbaum, S. G., Van Der A, D. L., Forouhi, N. G., Onland-Moret, N. C., Van Der Schouw, Y. T., Schnabel, R. B., Hubacek, J. A., Kubinova, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S., Baldassarre, D., Sennblad, B., Tremoli, E., De Faire, U., Veglia, F., Ford, I., Jukema, J. W., Westendorp, R. G. J., De Borst, G. J., De Jong, P. A., Algra, A., Spiering, W., Der Zee, A. H. M. V., Klungel, O. H., De Boer, A., Doevendans, P. A., Eaton, C. B., Robinson, J. G., Duggan, D., Kjekshus, J., Downs, J. R., Gotto, A. M., Keech, A. C., Marchioli, R., Tognoni, G., Sever, P. S., Poulter, N. R., Waters, D. D., Pedersen, T. R., Amarenco, P., Nakamura, H., McMurray, J. J. V., Lewsey, J. D., Chasman, D. I., Ridker, P. M., Maggioni, A. P., Tavazzi, L., Ray, K. K., Seshasai, S. R. K., Manson, J. E., Price, J. F., Whincup, P. H., Morris, R. W., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Schreiner, P. J., Fornage, M., Siscovick, D. S., Cushman, M., Kumari, M., Wareham, N. J., Verschuren, W. M. M., Redline, S., Patel, S. R., Whittaker, J. C., Hamsten, A., Delaney, J. A., Dale, C., Gaunt, T. R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B. A., Van Der Harst, P., Brunner, E. J., Tybjaerg-Hansen, A., Marmot, M. G., Krauss, R. M., Tsai, M., Coresh, J., Hoogeveen, R. C., Psaty, B. M., Lange, L. A., Hakonarson, H., Dudbridge, F., Humphries, S. E., Talmud, P. J., Kivimäki, M., Timpson, N. J., Langenberg, C., Asselbergs, F. W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J. G., Reiner, A. P., Keating, B. J., Hingorani, A. D. & Sattar, N., 24 Jan 2015, In : Lancet. 385, 9965, p. 351-361 11 p.

Research output: Contribution to journalArticle (Academic Journal)

333 Citations (Scopus)

Longitudinal analysis of DNA methylation associated with birth weight and gestational age

Simpkin, A. J., Suderman, M., Gaunt, T. R., Lyttleton, O., McArdle, W. L., Ring, S. M., Tilling, K., Smith, G. D. & Relton, C. L., 13 Apr 2015, In : Human Molecular Genetics. 24, 13, p. 3752-3763 12 p.

Research output: Contribution to journalArticle (Academic Journal)

62 Citations (Scopus)

Long term risk factors for coronary heart disease and stroke: Influence of duration of follow-up over four decades of mortality surveillance

Batty, G. D., Shipley, M., Smith, G. D. & Kivimaki, M., 12 Sep 2015, In : European Journal of Preventive Cardiology. 22, 9, p. 1139-1145 7 p.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)
26 Citations (Scopus)

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

Davies, N. M., Gaunt, T. R., Lewis, S. J., Holly, J. M. P., Donovan, J. L., Hamdy, F. C., Kemp, J. P., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, B. G., Travis, R. C. & 20 others, Neal, D., Pashayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Lathrop, M., Davey Smith, G., Martin, R. M. & the PRACTICAL Consortium, Nov 2015, In : Cancer Causes and Control. 26, p. 1603-1616 14 p.

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34 Citations (Scopus)
308 Downloads (Pure)

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 31 others, Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H-J., White, C. C., Absher, D., Ahluwalia, T. S., Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Cadby, G., Cheng, Y-C., Chiang, C. W. K., Paternoster, L., Wong, A., Cole, J. H., Kumari, M., McArdle, W. L., Kivimaki, M. J., Palmer, L. J., Sorensen, T. & CHARGE Consortium, Oct 2015, In : PLoS Genetics. 11, 10, 42 p., e1005378.

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132 Citations (Scopus)
269 Downloads (Pure)

The many weak instruments problem and Mendelian randomization

Davies, N. M., Von Hinke Kessler Scholder, S., Farbmacher, H., Burgess, S., Windmeijer, F. & Davey Smith, G., 10 Feb 2015, In : Statistics in Medicine. 34, 3, p. 454-468 15 p.

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37 Citations (Scopus)
321 Downloads (Pure)

The role of common genetic variation in educational attainment and income: evidence from the National Child Development Study

Davies, N. M., Hemani, G., Timpson, N. J., Windmeijer, F. & Davey Smith, G., 30 Nov 2015, In : Scientific Reports. 5, 12 p., 16509.

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7 Citations (Scopus)
317 Downloads (Pure)

Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with L-ascorbic acid

Wade, K. H., Forouhi, N. G., Cook, D. G., Johnson, P., McConnachie, A., Morris, R. W., Rodriguez, S., Ye, Z., Ebrahim, S., Padmanabhan, S., Watt, G., Bruckdorfer, K. R., Wareham, N. J., Whincup, P. H., Chanock, S., Sattar, N., Lawlor, D. A., Davey Smith, G. & Timpson, N. J., Jan 2015, In : American Journal of Clinical Nutrition. 101, 1, p. 202-9 8 p.

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7 Citations (Scopus)
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7 Citations (Scopus)
355 Downloads (Pure)
2014

Approaches for drawing causal inferences from epidemiological birth cohorts: a review

Richmond, R. C., Al-Amin, A., Smith, G. D. & Relton, C. L., Nov 2014, In : Early Human Development. 90, 11, p. 769-780 12 p.

Research output: Contribution to journalArticle (Academic Journal)

71 Citations (Scopus)

Association of common genetic variants with lipid traits in the Indian population

Walia, G. K., Gupta, V., Aggarwal, A., Asghar, M., Dudbridge, F., Timpson, N., Singh, N. S., Kumar, M. R., Kinra, S., Prabhakaran, D., Reddy, K. S., Chandak, G. R., Smith, G. D. & Ebrahim, S., 3 Jul 2014, In : PLoS ONE. 9, 7, e101688.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

Perry, J. R. B., Hsu, Y-H., Chasman, D. I., Elks, C., Albrecht, E., Andrulis, I. L., Beesley, J., Berenson, G. S., Bergmann, S., Bojesen, S. E., Bolla, M. K., Buring, J. E., Campbell, H., Chang-Claude, J., Chenevix-Trench, G., Corre, T., Couch, F. J., Cox, A., Czene, K., D'adamo, A. P. & 26 others, Davies, G., Deary, I. J., Dennis, J., Easton, D. F., Engelhardt, E. G., Eriksson, J. G., Esko, T., Fasching, P. A., Figueroa, J. D., Flyger, H., Fraser, A., Garcia-Closas, M., Gasparini, P., Gieger, C., Giles, G., Guenel, P., Hägg, S., Hall, P., Hayward, C., Hopper, J., Ingelsson, E., Kardia, S. L. R., Kasiman, K., Knight, J. A., Lawlor, D. A. & kConFab investigators, 1 May 2014, In : Human Molecular Genetics. 23, 9, p. 2490-7 8 p.

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)

Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin

Bolton, J. L., Hayward, C., Direk, N., Hill, L. A., Anderson, A., Huffman, J., Campbell, H., Rudan, I., Hastie, N., Wild, S. H., Velders, F. P., Hofman, A., Uitterlinden, A. G., Lahti, J., Räikkönen, K., Kajantie, E., Widen, E., Palotie, A., Eriksson, J. G., Kaakinen, M. & 27 others, Järvelin, M-R., Timpson, N. J., Davey Smith, G., Ring, S. M., Evans, D. M., St Pourcain, B., Tanaka, T., Milaneschi, Y., Bandinelli, S., Ferrucci, L., van der Harst, P., Rosmalen, J. G. M., Bakker, S. J. L., Verweij, N., Dullaart, R. P. F., Mahajan, A., Lindgren, C. M., Morris, A., Lind, L., Ingelsson, E., Anderson, L. N., Pennell, C. E., Lye, S. J., Matthews, S. G., Eriksson, J., Mellstrom, D. & CORtisol NETwork (CORNET) Consortium, Jul 2014, In : PLoS Genetics. 10, 7, p. e1004474

Research output: Contribution to journalArticle (Academic Journal)

55 Citations (Scopus)

Haptoglobin Duplicon, Hemoglobin, and Vitamin C: Analyses in the British Women's Heart and Health Study and Caerphilly Prospective Study

Guthrie, P. A. I., Abdollahi, M. R., Gaunt, T., Lawlor, D. A., Ben-Shlomo, Y., Gallacher, J., Davey Smith, G., Day, I. N. M. & Rodriguez, S., 2014, In : Disease Markers. 2014, p. 529456

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)

Instrumental variable analysis with a nonlinear exposure-outcome relationship

Burgess, S., Davies, N. M., Thompson, S. G. & EPIC InterAct Consortium, Nov 2014, In : Epidemiology. 25, 6, p. 877-85 9 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Gabrielsen, M. E., Skorpen, F., Marioni, R. E., Campbell, A., Engmann, J., Mirza, S. S., Loukola, A., Laatikainen, T., Partonen, T., Kaakinen, M., Ducci, F., Cavadino, A., Husemoen, L. L. N., Ahluwalia, T. S., Jacobsen, R. K., Skaaby, T., Ebstrup, J. F. & 42 others, Mortensen, E. L., Minica, C. C., Vink, J. M., Willemsen, G., Marques-Vidal, P., Dale, C. E., Amuzu, A., Lennon, L. T., Lahti, J., Palotie, A., Räikkönen, K., Wong, A., Paternoster, L., Wong, A. P-Y., Horwood, L. J., Murphy, M., Johnstone, E. C., Kennedy, M. A., Pausova, Z., Paus, T., Ben-Shlomo, Y., Nohr, E. A., Kuh, D., Kivimaki, M., Eriksson, J. G., Morris, R. W., Casas, J. P., Preisig, M., Boomsma, D. I., Linneberg, A., Power, C., Hyppönen, E., Veijola, J., Jarvelin, M-R., Korhonen, T., Tiemeier, H., Kumari, M., Porteous, D. J., Hayward, C., Romundstad, P. R., Smith, G. D. & Munafò, M. R., 2014, In : BMJ Open. 4, 10, e006141.

Research output: Contribution to journalArticle (Academic Journal)

58 Citations (Scopus)

Maternal diabetes in pregnancy and offspring cognitive ability: sibling study with 723,775 men from 579,857 families

Fraser, A., Almqvist, C., Larsson, H., Langstrom, N. & Lawlor, D. A., Jan 2014, In : Diabetologia. 57, 1, p. 102-109 8 p.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)
11 Citations (Scopus)

Mendelian randomization in health research: Using appropriate genetic variants and avoiding biased estimates

Taylor, A. E., Davies, N. M., Ware, J. J., Vanderweele, T., Smith, G. D. & Munafò, M. R., Mar 2014, In : Economics and Human Biology. 13, p. 99-106 8 p.

Research output: Contribution to journalArticle (Academic Journal)

62 Citations (Scopus)

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

Hoggart, C. J., Venturini, G., Mangino, M., Gomez, F., Ascari, G., Zhao, J. H. U., Teumer, A., Winkler, T. W., Tšernikova, N., Luan, J., Mihailov, E., Ehret, G. B., Zhang, W., Lamparter, D., Esko, T., Macé, A., Rüeger, S., Bochud, P. Y., Barcella, M., Dauvilliers, Y. & 63 others, Benyamin, B., Evans, D. M., Hayward, C., Lopez, M. F., Franke, L., Russo, A., Heid, I. M., Salvi, E., Vendantam, S., Arking, D. E., Boerwinkle, E., Chambers, J. C., Fiorito, G., Grallert, H., Guarrera, S., Homuth, G., Huffman, J. E., Porteous, D., Moradpour, D., Iranzo, A., Hebebrand, J., Kemp, J. P., Lammers, G. J., Aubert, V., Heim, M. H., Martin, N. G., Montgomery, G. W., Peraita-Adrados, R., Santamaria, J., Negro, F., Schmidt, C. O., Scott, R. A., Spector, T. D., Strauch, K., Völzke, H., Wareham, N. J., Yuan, W., Bell, J. T., Chakravarti, A., Kooner, J. S., Peters, A., Matullo, G., Wallaschofski, H., Whitfield, J. B., Paccaud, F., Vollenweider, P., Bergmann, S., Beckmann, J. S., Tafti, M., Hastie, N. D., Cusi, D., Bochud, M., Frayling, T. M., Metspalu, A., Jarvelin, M. R., Scherag, A., Borecki, I. B., Rousson, V., Hirschhorn, J. N., Rivolta, C., Loos, R. J. F., Kutalik, Z. & Davey Smith, G., 1 Jul 2014, In : PLoS Genetics. 10, 7, p. e1004508

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)

Pregnancy characteristics and women's future cardiovascular health: an underused opportunity to improve women's health?

Rich-Edwards, J. W., Fraser, A., Lawlor, D. A. & Catov, J. M., 2014, In : Epidemiological Reviews. 36, p. 57-70 14 p.

Research output: Contribution to journalArticle (Academic Journal)

163 Citations (Scopus)

Prenatal alcohol exposure and childhood atopic disease: A Mendelian randomization approach

Shaheen, S. O., Rutterford, C., Zuccolo, L., Ring, S. M., Smith, G. D., Holloway, J. W. & Henderson, A. J., Jan 2014, In : Journal of Allergy and Clinical Immunology. 133, 1, p. 225-+ 13 p.

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

Rapid increases in infant adiposity and overweight/obesity in childhood are associated with higher central and brachial blood pressure in early adulthood

Howe, L. D., Chaturvedi, N., Lawlor, D. A., Santos Ferreira, D. L., Fraser, A., Davey Smith, G., Tilling, K. & Hughes, A. D., Sep 2014, In : Journal of Hypertension. 32, 9, p. 1789-96 8 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: Application to alcohol and cardiovascular traits

Silverwood, R. J., Holmes, M. V., Dale, C. E., Lawlor, D. A., Whittaker, J. C., Smith, G. D., Leon, D. A., Palmer, T., Keating, B. J., Zuccolo, L., Casas, J. P. & Dudbridge, F., 1 Dec 2014, In : International Journal of Epidemiology. 43, 6, p. 1781-1790 10 p., dyu187.

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31 Citations (Scopus)

The association between primary tooth emergence and anthropometric measures in young adults: Findings from a large prospective cohort study

Fatemifar, G., Evans, D. M. & Tobias, J. H., 13 May 2014, In : PLoS ONE. 9, 5, p. e96355 e96355.

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2 Citations (Scopus)
2013

A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array

Gaunt, T. R., Lowe, G. D. O., Lawlor, D. A., Casas, J-P. & Day, I. N. M., 2013, In : European Journal of Human Genetics. 21, p. 779-783

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)

Analysis of Body Composition in Individuals With High Bone Mass Reveals a Marked Increase in Fat Mass in Women But Not Men

Gregson, C. L., Paggiosi, M. A., Crabtree, N., Steel, S. A., McCloskey, E., Duncan, E. L., Fan, B., Shepherd, J. A., Fraser, W. D., Smith, G. D. & Tobias, J. H., 1 Feb 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 2, p. 818-828 10 p., 98(2).

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)

Anti-müllerian hormone is not associated with cardiometabolic risk factors in adolescent females

Anderson, E. L., Fraser, A., McNally, W., Sattar, N., Lashen, H., Fleming, R., Nelson, S. M. & Lawlor, D. A., 2013, In : PLoS ONE. 8, 5, p. e64510

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)

Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals

Khan, T. A., Shah, T., Prieto, D., Zhang, W., Price, J., Fowkes, G. R., Cooper, J., Talmud, P. J., Humphries, S. E., Sundstrom, J., Hubacek, J. A., Ebrahim, S., Lawlor, D. A., Ben-Shlomo, Y., Abdollahi, M. R., Slooter, A. J., Szolnoki, Z., Sandhu, M., Wareham, N., Frikke-Schmidt, R. & 29 others, Tybjærg-Hansen, A., Fillenbaum, G., Heijmans, B. T., Katsuya, T., Gromadzka, G., Singleton, A., Ferrucci, L., Hardy, J., Worrall, B., Rich, S. S., Matarin, M., Whittaker, J., Gaunt, T. R., Whincup, P., Morris, R., Deanfield, J., Donald, A., Davey Smith, G., Kivimaki, M., Kumari, M., Smeeth, L., Khaw, K-T., Nalls, M., Meschia, J., Sun, K., Hui, R., Day, I., Hingorani, A. D. & Casas, J. P., Apr 2013, In : International Journal of Epidemiology. 42, 2, p. 475-492 18 p.

Research output: Contribution to journalArticle (Academic Journal)

80 Citations (Scopus)

Association between Milk and Milk Product Consumption and Anthropometric Measures in Adult Men and Women in India: A Cross-Sectional Study

Satija, A., Agrawal, S., Bowen, L., Khandpur, N., Kinra, S., Prabhakaran, D., Reddy, K. S., Smith, G. D. & Ebrahim, S., 8 Apr 2013, In : PLoS ONE. 8, 4, 16 p., 60739.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)