Characterisation of neutrophils from malaria patients

We will isolate neutrophils from patients with Plasmodium falciparum malaria in order to analyse functional responses and intracellular signalling pathways.

Malaria is a widespread parasitic disease affecting over 200 million people in developing countries, largely in sub Saharan Africa. Neutrophils are immune cells that contribute to malaria pathogenesis by driving inflammation. We will characterise neutrophils from malaria patients in order to better characterise the inflammatory response.