Chemo-enzymatic Production of Specialty Glycans.

Galan, M C (Principal Investigator)

School of Chemistry

Status	Finished
Effective start/end date	19/10/15 → 18/04/21
Links	http://gtr.rcuk.ac.uk/projects?ref=BB/M028976/1

Research Groups and Themes

Organic & Biological
Bristol BioDesign Institute

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5 Article (Academic Journal)

Synthesis and screening of a library of Lewis^x deoxyfluoro-analogues reveals differential recognition by glycan-binding partners
Hollingsworth, K., Di Maio, A., Richards, S.-J., Vendeville, J.-B., Wheatley, D. E., Council, C. E., Keenan, T., Ledru, H., Chidwick, H., Huang, K., Parmeggiani, F., Marchesi, A., Chai, W., McBerney, R., Kamiński, T. P., Balmforth, M. R., Tamasanu, A., Finnigan, J. D., Young, C. & Warriner, S. L. & 9 others, Webb, M. E., Fascione, M. A., Flitsch, S., Galan, M. C., Feizi, T., Gibson, M. I., Liu, Y., Turnbull, W. B. & Linclau, B., 13 Sept 2024, In: Nature Communications. 15, 1, 14 p., 7925.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
12 Citations (Scopus)
Biocatalytic Transfer of Pseudaminic Acid (Pse5Ac7Ac) Using Promiscuous Sialyltransferases in a Chemoenzymatic Approach to Pse5Ac7Ac-Containing Glycosides
Flack, E. K. P., Chidwick, H. S., Guchhait, G., Keenan, T., Budhadev, D., Huang, K., Both, P., Mas Pons, J., Ledru, H., Rui, S., Stafford, G. P., Shaw, J. G., Galan, M. C., Flitsch, S., Thomas, G. H. & Fascione, M. A., 4 Sept 2020, In: ACS Catalysis. 10, 17, p. 9986-9993 8 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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12 Citations (Scopus)

116 Downloads (Pure)
Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides
Huang, K., Marchesi, A., Hollingsworth, K., Both, P., Mattey, A. P., Pallister, E., Ledru, H., Charnock, S. J., Galan, M. C., Turnbull, W. B., Parmeggiani, F. & Flitsch, S. L., 30 Mar 2020, In: Organic and Biomolecular Chemistry. 18, 16, p. 3142-3148 7 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

File
11 Citations (Scopus)

58 Downloads (Pure)

Chemo-enzymatic Production of Specialty Glycans.

Project Details

Research Groups and Themes

Access Project

Fingerprint

Synthesis and screening of a library of Lewis^x deoxyfluoro-analogues reveals differential recognition by glycan-binding partners

Biocatalytic Transfer of Pseudaminic Acid (Pse5Ac7Ac) Using Promiscuous Sialyltransferases in a Chemoenzymatic Approach to Pse5Ac7Ac-Containing Glycosides

Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides

Chemo-enzymatic Production of Specialty Glycans.

Project Details

Research Groups and Themes

Access Project

Fingerprint

Research output

Synthesis and screening of a library of Lewisx deoxyfluoro-analogues reveals differential recognition by glycan-binding partners

Biocatalytic Transfer of Pseudaminic Acid (Pse5Ac7Ac) Using Promiscuous Sialyltransferases in a Chemoenzymatic Approach to Pse5Ac7Ac-Containing Glycosides

Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides

Synthesis and screening of a library of Lewis^x deoxyfluoro-analogues reveals differential recognition by glycan-binding partners