Defining the mechanistic and functional details of an evolutionarily conserved non-canonical retromer pathway.

Status	Finished
Effective start/end date	12/12/11 → 12/12/14

SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion
McGough, I. J., de Groot, R. E. A., Jellett, A. P., Betist, M. C., Varandas, K. C., Danson, C. M., Heesom, K. J., Korswagen, H. C. & Cullen, P. J., 13 Sept 2018, In: Nature Communications. 9, 13 p., 3737.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

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53 Citations (Scopus)

363 Downloads (Pure)
A defect in the retromer accessory protein, SNX27, manifests by infantile myoclonic epilepsy and neurodegeneration
Damseh, N., Danson, C. M., Al-Ashhab, M., Abu-Libdeh, B., Gallon, M., Sharma, K., Yaacov, B., Caldwell, M. A., Edvardson, S., Cullen, P. J., Elpeleg, O. & Coulthard, E., Jul 2015, In: neurogenetics. 16, 3, p. 215-21 7 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
40 Citations (Scopus)
Retromer: A Master Conductor of Endosome Sorting
Burd, C. & Cullen, P. J., Feb 2014, In: Cold Spring Harbor Perspectives in Biology. 6, 2, 13 p., 016774.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
337 Citations (Scopus)

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