ELUCIDATION OF THE ROLE OF KAINATE RECEPTORS IN HIPPOCAMPAL SYNAPTIC MECHANISMS USING NOVEL PHARMACOLOGICAL TOOLS

Status	Finished
Effective start/end date	1/10/04 → 1/01/08

Inhibition of kainate receptors reduces the frequency of hippocampal theta oscillations
Huxter, JR., Zynyuk, LE., Roloff, E., Clarke, VRJ., Dolman, NP., More, JC-A., Jane, DE., Collingridge, GL. & Muller, RL., Feb 2007, In: Journal of Neuroscience. 27 (9), p. 2212 - 2223 12 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
28 Citations (Scopus)
Synthesis and Pharmacological Characterization of N³-Substituted Willardiine Derivatives: Role of the Substituent at the 5-Position of the Uracil Ring in the Development of Highly Potent and Selective GLU_K5 Kainate Receptor Antagonists
Dolman, NP., More, JC-A., Alt, A., Knauss, JL., Pentikäinen, OT., Glasser, CR., Bleakman, D., Mayer, ML., Collingridge, GL. & Jane, DE., Apr 2007, In: Journal of Medicinal Chemistry. 50 (7), p. 1558 - 1570 13 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

64 Citations (Scopus)
Crystal structures of the kainate receptor GluR5 ligand binding core dimer complex with novel GluR5-selective antagonists
Mayer, ML., Ghosal, A., Dolman, NP. & Jane, DE., 15 Mar 2006, In: Journal of Neuroscience. 26 (11), p. 2852 - 2861 10 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

98 Citations (Scopus)

Project Details