Evaluating the role of DNA methylation changes in very early preterm birth

Preterm birth (PTB) is one of the most troublesome clinical, perinatal,
population, and global health problems of the 21st century affecting 10% of births in the United States and up to 15% of births in Low- and Middle-Income Countries. This study assesses the environmental and epigenetic determinants of early PTB. Identifying the biological mechanisms of PTB will allow the development of interventions to prevent PTB's immediate and long-term consequences, particularly in high-risk populations.