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Functional validation of novel osteo-anabolic factors in the zebrafish

  • Bergen, Dylan J M (Principal Investigator)

Project Details

Description

Genes derived from my in silico prioritisation pipeline will be studied in the zebrafish model as part of my Foundation Fellowship from Versus Arthritis.
I will also use zebrafish scales to study bone regeneration processes.
StatusActive
Effective start/end date1/04/19 → …

Research Groups and Themes

  • Developmental (Psychological Science)
  • Zebrafish
  • Bone
  • Osteoblast
  • Genes
  • Osteoporosis

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  • 4 Review article (Academic Journal)
  • 3 Article (Academic Journal)

  • High Bone Mass Disorders: New Insights from Connecting the Clinic and the Bench

    Bergen, D. J. M., Maurizi, A., Formosa, M. M., Mcdonald, G., El-Gazzar, A., Hassan, N., Brandi, M.-L., Riancho, J. A., Rivadeneira, F., Ntzani, E., Duncan, E. L., Gregson, C. L., Kiel, D. P., Zillikens, M. C., Sangiorgi, L., Högler, W., Duran, I., Mäkitie, O., van Hul, W. & Hendrickx, G., 26 Sept 2022, (E-pub ahead of print) In: Journal of Bone and Mineral Research.

    Research output: Contribution to journal › Review article (Academic Journal) › peer-review

    Open Access
    File
    15 Citations (Scopus)
    117 Downloads (Pure)

  • Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease

    Bergen, D. J. M., Tong, Q., Shukla, A., Newham, E., Zethof, J., Lundberg, M., Ryan, R., Youlten, S. E., Frysz, M., Croucher, P. I., Flik, G., Richardson, R. J., Kemp, J. P., Hammond, C. L. & Metz, J. R., 21 Jan 2022, In: BMC Biology. 20, 1, 25 p., 21.

    Research output: Contribution to journal › Article (Academic Journal) › peer-review

    Open Access
    File
    33 Citations (Scopus)
    206 Downloads (Pure)

  • A Roadmap to Gene Discoveries and Novel Therapies in Monogenic Low and High Bone Mass Disorders

    Formosa, M., Bergen, D. J. M., Gregson, C. L., Maurizi, A., Kampe, A., Garcia-Giralt, N., Zhou, W., Grindberg, D., Ovejero Crespo, D., Zilikens, M. C., Williams, G., Bassett, J. H. D., Brandi, M. L., Sangiorgi, L., Hogler, W., van Hul, W. & Mäkitie, O., 13 Aug 2021, In: Frontiers in Endocrinology. 12, 709711.

    Research output: Contribution to journal › Review article (Academic Journal) › peer-review

    Open Access
    File
    26 Citations (Scopus)
    249 Downloads (Pure)
View all 7 research outputs