Identifying the role of NMDA receptors in STP through investigation of synaptic plasticity and discovery of novel subtype-specific antagonists

Jane, David E (Principal Investigator)

Status	Finished
Effective start/end date	28/02/14 → 30/07/17
Links	http://gtr.rcuk.ac.uk/projects?ref=BB/L001977/1

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6 Article (Academic Journal)
2 Review article (Academic Journal)

Positive and Negative Allosteric Modulators of N-Methyl- d -aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action
Burnell, E. S., Irvine, M., Fang, G., Sapkota, K., Jane, D. E. & Monaghan, D. T., 10 Jan 2019, In: Journal of Medicinal Chemistry. 62, 1, p. 3-23 21 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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59 Citations (Scopus)

456 Downloads (Pure)
A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors
Chopra, D. A., Sapkota, K., Irvine, M. W., Fang, G., Jane, D. E., Monaghan, D. T. & Dravid, S. M., 31 Jul 2017, In: Scientific Reports. 7, 11 p., 6933.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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11 Citations (Scopus)

353 Downloads (Pure)
Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives
Sapkota, K., Irvine, M. W., Fang, G., Burnell, E. S., Bannister, N., Volianskis, A., Culley, G. R., Dravid, S. M., Collingridge, G. L., Jane, D. E. & Monaghan, D. T., Oct 2017, In: Neuropharmacology. 125, p. 64-79 16 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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18 Citations (Scopus)

305 Downloads (Pure)