(IEU) Epigenetics: Environment, Embodiment & Equality (E4)

2022

The EWAS Catalog: a database of epigenome-wide association studies

Battram, T., Yousefi, P., Crawford, G., Prince, C., Sheikhali Babaei, M., Sharp, G., Hatcher, C., Vega-Salas, M. J., Khodabakhsh, S., Whitehurst, O., Langdon, R., Mahoney, L., Elliott, H. R., Mancano, G., Lee, M. A., Watkins, S. H., Lay, A. C., Hemani, G., Gaunt, T. R. & Relton, C. L. & 2 others, Staley, J. R. & Suderman, M., 31 May 2022, In: Wellcome Open Research. 7, p. 41

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

116 Citations (Scopus)

242 Downloads (Pure)

2020

Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children

Marini, S., Davis, K. A., Soare, T. W., Zhu, Y., Suderman, M. J., Simpkin, A. J., Smith, A. D. A. C., Wolf, E. J., Relton, C. L. & Dunn, E. C., 1 Mar 2020, In: Psychoneuroendocrinology. 113, 104484.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

109 Citations (Scopus)

Ancestral childhood environmental exposures occurring to the grandparents and great-grandparents of the ALSPAC study children

Golding, J., Gregory, S., Matthews, S. M., Smith, D., Suarez Perez, A., Bowring, C. E., Iles-Caven , Y. L., Birmingham, K. E., Pembrey, M. E., Suderman, M. J. & Northstone, K., 4 Sept 2020, In: Wellcome Open Research. 5, 207, 18 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

6 Citations (Scopus)

116 Downloads (Pure)

Associations of adverse childhood experiences with educational attainment and adolescent health and the role of family and socioeconomic factors: A prospective cohort study in the UK

Houtepen, L. C., Heron, J., Suderman, M. J., Fraser, A., Chittleborough, C. R. & Howe, L. D., 2 Mar 2020, In: PLoS Medicine. 17, 3, p. e1003031

Research output: Contribution to journal › Article (Academic Journal) › peer-review

168 Citations (Scopus)

DNA methylation signature of passive smoke exposure is less pronounced than active smoking: the Understanding Society study

Hulls, P. M., de Vocht , F., Bao, Y., Relton, C. L., Martin, R. M. & Richmond, R., 1 Nov 2020, In: Environmental Research. 190, 10 p., 109971.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

12 Citations (Scopus)

128 Downloads (Pure)

Epigenome-wide association study of seizures in childhood and adolescence

Caramaschi, D., Hatcher, C., Mulder, R. H., Felix, J. F., Cecil, C. A. M., Relton, C. L. & Walton, E., 8 Jan 2020, In: Clinical Epigenetics. 12, 13 p., 8 (2020).

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

12 Citations (Scopus)

187 Downloads (Pure)

Epigenomics of being bullied: changes in DNA methylation following bullying exposure

Mulder, R. H., Walton, E., Neumann, A., Houtepen, L. C., Felix, J. F., Bakermans-Kranenburg, M. J., Suderman, M., Tiemeier, H., van IJzendoorn, M. H., Relton, C. L. & Cecil, C. A. M., 28 Jan 2020, (E-pub ahead of print) In: Epigenetics. 15 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

19 Citations (Scopus)

162 Downloads (Pure)

Impact of sex hormone-binding globulin on the human phenome

Arathimos, R., Millard, L. A. C., Bell, J. A., Relton, C. L. & Suderman, M., 21 Jul 2020, In: Human Molecular Genetics. 29, 11, p. 1824-1832 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

17 Citations (Scopus)

Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways

Jamieson, E., Korologou-Linden, R., Wootton, R. E., Guyatt, A. L., Battram, T., Burrows, K., Gaunt, T. R., Tobin, M. D., Munafò, M., Davey Smith, G., Tilling, K., Relton, C., Richardson, T. G. & Richmond, R. C., 5 Mar 2020, In: American Journal of Human Genetics. 106, 3, p. 315-326 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

38 Citations (Scopus)

120 Downloads (Pure)

The association of DNA methylation with body mass index: distinguishing between predictors and biomarkers

Reed, Z. E., Suderman, M. J., Relton, C. L., Davis, O. S. P. & Hemani, G., 30 Mar 2020, In: Clinical Epigenetics. 12, 50 (2020), 13 p., 50 (2020).

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

44 Citations (Scopus)

108 Downloads (Pure)

2019

An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility

Richardson, T. G., Richmond, R. C., North, T. L., Hemani, G., Davey Smith, G., Sharp, G. C. & Relton, C. L., 29 Jun 2019, In: International Journal of Epidemiology. 48, 3, p. 887-898 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

12 Citations (Scopus)

466 Downloads (Pure)

A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57

Irwin, R., Thursby, S.-J., Ondičová, M., Pentieva, K., McNulty, H., Richmond, R., Caffrey, A., Lees-Murdock, D., McLaughlin, M., Cassidy, T., Suderman, M., Relton, C. & Walsh, C., 1 Dec 2019, In: Clinical Epigenetics. 11, 1, 16 p., 31.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

42 Citations (Scopus)

372 Downloads (Pure)

Changes in DNA methylation from pre-to post-adolescence are associated with pubertal exposures

Han, L., Zhang, H., Kaushal, A., Rezwan, F. I., Kadalayil, L., Karmaus, W., Henderson, A. J., Relton, C. L., Ring, S., Arshad, S. H., Ewart, S. L. & Holloway, J. W., 2 Dec 2019, In: Clinical Epigenetics. 11, 1, 176.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

41 Citations (Scopus)

143 Downloads (Pure)

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

Sikdar, S., Joehanes, R., Joubert, B. R., Xu, C.-J., Vives-Usano, M., Rezwan, F. I., Felix, J. F., Ward, J. M., Guan, W., Richmond, R. C., Brody, J. A., Kupers, L. K., Baïz, N., Haberg, S. E., Smith, J. A., Reese, S. E., Aslibekyan, S., Hoyo, C., Dhingra, R. & Markunas, C. A. & 2 others, Relton, C. L. & al., E., 19 Sept 2019, (E-pub ahead of print) In: Epigenomics. 11, 13, p. 1487-1500 14 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

69 Citations (Scopus)

159 Downloads (Pure)

DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

Wiklund, P., Karhunen, V., Richmond, R. C., Parmar, P., Rodriguez, A., De Silva, M., Wielscher, M., Rezwan, F. I., Richardson, T. G., Veijola, J., Herzig, K. H., Holloway, J. W., Relton, C. L., Sebert, S. & Järvelin, M. R., 1 Jul 2019, In: Clinical Epigenetics. 11, 1, 16 p., 97.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

97 Citations (Scopus)

220 Downloads (Pure)

DNA Methylation Signatures of Breastfeeding in Buccal Cells Collected in Mid-Childhood

Odintsova, V., Hagenbeek, F. A., Suderman, M., Caramaschi, D., Beijsterveldt, C. E. M. V., Kallsen, N. A., Ehli, E. A., Davies, G. E., Sukhikh, G. T., Fanos, V., Relton, C., Bartels, M., Boomsma, D. I. & van Dongen, J., 17 Nov 2019, In: Nutrients. 11, 11, 26 p., 2804.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

17 Citations (Scopus)

126 Downloads (Pure)

Genetic and observational evidence supports a causal role of sex hormones on the development of asthma

Arathimos, R., Granell, R., Haycock, P., Richmond, R., Yarmolinsky, J., Relton, C. & Tilling, K., 1 Jul 2019, In: Thorax. 74, 7, p. 633-642 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

29 Citations (Scopus)

231 Downloads (Pure)

Investigating the impact of cigarette smoking behaviours on DNA methylation patterns in adolescence

Prince, C., Hammerton, G., Taylor, A. E., Anderson, E. L., Timpson, N. J., Davey Smith, G., Munafò, M. R., Relton, C. L. & Richmond, R. C., Jan 2019, In: Human Molecular Genetics. 28, 1, p. 155-165 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

15 Citations (Scopus)

355 Downloads (Pure)

Longitudinal investigation of DNA methylation changes preceding adolescent psychotic experiences

Roberts, S., Suderman, M., Zammit, S., Watkins, S. H., Hannon, E., Mill, J., Relton, C., Arseneault, L., Wong, C. C. Y. & Fisher, H. L., 4 Feb 2019, In: Translational Psychiatry. 9, 1, 12 p., 69.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

15 Citations (Scopus)

321 Downloads (Pure)

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Küpers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C. V., Allard, C., Just, A. C., Bakulski, K. M. & Holloway, J. W. & 107 others, Everson, T. M., Xu, C. J., Huang, R. C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F. I., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M. R., Bergström, A., Örtqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Håberg, S. E., Sørensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I. V., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D. I., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melén, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M. F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Davey Smith, G., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 23 Apr 2019, In: Nature Communications. 10, 1, 11 p., 1893.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

149 Citations (Scopus)

301 Downloads (Pure)

Methods for Dealing with Missing Covariate Data in Epigenome-Wide Association Studies

Mills, H., Heron, J., Relton, C., Suderman, M. & Tilling, K., 5 Sept 2019, In: American Journal of Epidemiology. 23 p., kwz186.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

4 Citations (Scopus)

184 Downloads (Pure)

Pathways between early-life adversity and adolescent self-harm: the mediating role of inflammation in the Avon Longitudinal Study of Parents and Children

Russell, A. E., Heron, J., Gunnell, D., Ford, T., Hemani, G., Joinson, C., Moran, P., Relton, C., Suderman, M. & Mars, B., 12 Sept 2019, In: Journal of Child Psychology and Psychiatry. 60, 10, p. 1094-1103 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

42 Citations (Scopus)

230 Downloads (Pure)

Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis

Gruzieva, O., Xu, C.-J., Yousefi, P., Relton, C., Merid, S. K., Breton, C. V., Gao, L., Volk, H. E., Feinberg, J. I., Ladd-Acosta, C., Bakulski, K., Auffray, C., Lemonnier, N., Plusquin, M., Ghantous, A., Herceg, Z., Nawrot, T. S., Pizzi, C., Richiardi, L. & Rusconi, F. & 31 others, Vineis, P., Kogevinas, M., Felix, J. F., Duijts, L., den Dekker, H. T., Jaddoe, V. W. V., Ruiz, J. L., Bustamante, M., Antó, J. M., Sunyer, J., Vrijheid, M., Gutzkow, K. B., Grazuleviciene, R., Hernandez-Ferrer, C., Annesi-Maesano, I., Lepeule, J., Bousquet, J., Bergström, A., Kull, I., Söderhäll, C., Kere, J., BIOS Consortium, Gehring, U., Brunekreef, B., Just, A. C., Wright, R. J., Peng, C., Gold, D. R., Kloog, I., DeMeo, D. L. & Pershagen, G., 31 May 2019, In: Environmental Health Perspectives. 127, 5, 12 p., 057012.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

126 Citations (Scopus)

283 Downloads (Pure)

Residential exposure to radon and DNA methylation across the lifecourse: an exploratory study in the ALSPAC birth cohort

de Vocht, F., Suderman, M., Ruano-Ravina, A., Thomas, R., Wakeford, R., Relton, C., Tilling, K. & Boyd, A., 7 Jan 2019, In: Wellcome Open Research. 4, p. 3 13 p., 3.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

9 Citations (Scopus)

239 Downloads (Pure)

Sensitive Periods for the Effect of Childhood Adversity on DNA Methylation: Results From a Prospective, Longitudinal Study

Dunn, E. C., Soare, T. W., Zhu, Y., Simpkin, A. J., Suderman, M. J., Klengel, T., Smith, A. D. A. C., Ressler, K. J. & Relton, C. L., 15 May 2019, In: Biological Psychiatry. 85, 10, p. 838-849 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

204 Citations (Scopus)

646 Downloads (Pure)

Socioeconomic position during pregnancy and DNA methylation signatures at three stages across the early life: Epigenome-wide association studies in the ALSPAC birth cohort

Alfano, R., Guida, F., Galobardes, B., Chadeau-Hyam, M., Delpierre, C., Ghantous, A., Henderson, J., Herceg, Z., Jain, P., Nawrot, T. S., Relton, C., Vineis, P., Castagne, R. & Plusquin, M., 1 Feb 2019, In: International Journal of Epidemiology. 48, 1, p. 30-44 15 p., dyy259.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

46 Citations (Scopus)

217 Downloads (Pure)

Validation and characterization of a DNA methylation alcohol biomarker across the life course

Yousefi, P. D., Richmond, R., Langdon, R., Ness, A., Liu, C., Levy, D., Relton, C., Suderman, M. & Zuccolo, L., 27 Nov 2019, In: Clinical Epigenetics. 11, 1, p. 163 12 p., 163 (2019).

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

15 Citations (Scopus)

212 Downloads (Pure)

2018

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Parmar, P. & BIOS Consortium, Dec 2018, In: EBioMedicine. 38, p. 206-216 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

26 Citations (Scopus)

226 Downloads (Pure)

Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation

Arathimos, R., Sharp, G., Granell, R., Tilling, K. & Relton, C., 14 Dec 2018, In: BMC Genetics. 19, 11 p., 113.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

19 Citations (Scopus)

303 Downloads (Pure)

Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure

Murtagh, M. J., Blell, M. T., Butters, O. W., Cowley, L., Dove, E. S., Goodman, A., Griggs, R. L., Hall, A., Hallowell, N., Kumari, M., Mangino, M., Maughan, B., Mills, M. C., Minion, J. T., Murphy, T., Prior, G., Suderman, M., Ring, S. M., Rogers, N. T. & Roberts, S. J. & 6 others, Van der Straeten, C., Viney, W., Wiltshire, D., Wong, A., Walker, N. & Burton, P. R., 26 Apr 2018, In: Human Genomics. 12, 12 p., 24.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

38 Citations (Scopus)

330 Downloads (Pure)

DNA methylation as a marker for prenatal smoke exposure in adults

Richmond, R., Suderman, M., Langdon, R., Relton, C. & Davey Smith, G., 31 May 2018, (E-pub ahead of print) In: International Journal of Epidemiology.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

88 Citations (Scopus)

341 Downloads (Pure)

DNA methylation from birth to late adolescence and development of multiple-risk behaviours

De Vocht, F., Suderman, M., Tilling, K., Heron, J., Howe, L., Campbell, R., Hickman, M. & Relton, C., Feb 2018, In: Journal of Affective Disorders. 227, p. 588-594 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

9 Citations (Scopus)

370 Downloads (Pure)

DRD4 methylation as a potential biomarker for physical aggression: An epigenome-wide, cross-tissue investigation

Cecil, C. A. M., Walton, E., Pingault, J.-B., Provençal, N., Pappa, I., Vitaro, F., Côté, S., Szyf, M., Tremblay, R. E., Tiemeier, H., Viding, E. & McCrory, E. J., Dec 2018, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 177, 8, p. 746-764 19 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

23 Citations (Scopus)

281 Downloads (Pure)

Epigenetic gestational age acceleration: A prospective cohort study investigating associations with familial, sociodemographic and birth characteristics

Khouja, J. N., Simpkin, A. J., O'Keeffe, L. M., Wade, K. H., Houtepen, L. C., Relton, C. L., Suderman, M. & Howe, L. D., 27 Jun 2018, In: Clinical Epigenetics. 10, 2 p., 86.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

44 Citations (Scopus)

300 Downloads (Pure)

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes

Ye, J., Richardson, T. G., McArdle, W. L., Relton, C. L., Gillespie, K. M., Suderman, M. & Hemani, G., 1 Sept 2018, In: Journal of Autoimmunity. 93, p. 66-75 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

26 Citations (Scopus)

429 Downloads (Pure)

Longitudinal analysis strategies for modelling epigenetic trajectories

Staley, J. R., Suderman, M., Simpkin, A., Gaunt, T., Heron, J., Relton, C. & Tilling, K., 16 Feb 2018, (E-pub ahead of print) In: International Journal of Epidemiology. 23 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

9 Citations (Scopus)

333 Downloads (Pure)

Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts

Sharp, G., Arathimos, R., Reese, S., Page, C., Felix, J. F., Kupers, L., Rifas-Shiman, S. L., Liu, C., Burrows, K., Zhao, S., Magnus, M., Duijts, L., Corpeleijn, E., DeMeo, D., Litonjua, A., Baccarelli, A., Hivert, M.-F., Oken, E., Snieder, H. & Jaddoe, V. W. V. & 4 others, Nystad, W., London, S., Relton, C. & Zuccolo, L., 18 Jan 2018, In: Epigenomics.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

55 Citations (Scopus)

308 Downloads (Pure)

Meffil: efficient normalization and analysis of very large DNA methylation datasets

Min, J., Hemani, G., Davey Smith, G., Relton, C. & Suderman, M., 21 Jun 2018, (E-pub ahead of print) In: Bioinformatics. 5 p., bty476.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

188 Citations (Scopus)

375 Downloads (Pure)

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease

Richardson, T. G., Haycock, P. C., Zheng, J., Timpson, N. J., Gaunt, T. R., Smith, G. D., Relton, C. L. & Hemani, G., Sept 2018, In: Human Molecular Genetics. 27, 18, p. 3293-3304 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

40 Citations (Scopus)

304 Downloads (Pure)

The long-term impact of folic acid in pregnancy on offspring DNA methylation: follow-up of the Aberdeen folic acid supplementation trial (AFAST)

Richmond, R., Sharp, G., Herbert, G., Atkinson, C., Taylor, C., Bhattachrya, S., Campbell, D., Hall, M., Kazmi, N., Gaunt, T., McArdle, W., Ring, S., Davey Smith, G., Ness, A. R. & Relton, C., 12 Mar 2018, (E-pub ahead of print) In: International Journal of Epidemiology. 47, 3

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

60 Citations (Scopus)

427 Downloads (Pure)

The value of biosamples in smoking cessation trials: a review of genetic, metabolomic, and epigenetic findings

Saccone, N. L., Baurley, J. W., Bergen, A. W., David, S. P., Elliott, H. R., Foreman, M. G., Kaprio, J., Piasecki, T. M., Relton, C. L., Zawertailo, L., Bierut, L. J., Tyndale, R. F. & Chen, L. S., 6 Mar 2018, In: Nicotine and Tobacco Research. 20, 4, p. 403-413 11 p., ntx096.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

19 Citations (Scopus)

396 Downloads (Pure)

Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data

Marioni, R. E., Suderman, M., Chen, B. H., Horvath, S., Bandinelli, S., Morris, T., Beck, S., Ferrucci, L., Pedersen, N. L., Relton, C. L., Deary, I. J. & Hägg, S., 20 Mar 2018, (E-pub ahead of print) In: Journals of Gerontology, Series A.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

75 Citations (Scopus)

334 Downloads (Pure)

2017

An epigenome-wide association study meta-analysis of educational attainment

Karlsson Linnér, R., Marioni, R. E., Rietveld, C. A., Simpkin, A. J., Davies, N. M., Watanabe, K., Armstrong, N. J., Auro, K., Baumbach, C., Bonder, M. J., Buchwald, J., Fiorito, G., Ismail, K., Iurato, S., Joensuu, A., Karell, P., Kasela, S., Lahti, J., McRae, A. F. & Mandaviya, P. R. & 31 others, Seppälä, I., Wang, Y., Baglietto, L., Binder, E. B., Harris, S. E., Hodge, A. M., Horvath, S., Hurme, M., Johannesson, M., Latvala, A., Mather, K. A., Medland, S. E., Metspalu, A., Milani, L., Milne, R. L., Pattie, A., Pedersen, N. L., Peters, A., Polidoro, S., Räikkönen, K., Severi, G., Starr, J. M., Stolk, L., Waldenberger, M., Eriksson, J. G., Esko, T., Franke, L., Gieger, C., Relton, C., Davey Smith, G. & BIOS Consortium, 31 Oct 2017, (E-pub ahead of print) In: Molecular Psychiatry. 22, p. 1680-1690

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

62 Citations (Scopus)

618 Downloads (Pure)

Are objective measures of physical capability related to accelerated epigenetic age? Findings from a British birth cohort

Simpkin, A. J., Cooper, R., Howe, L. D., Relton, C. L., Davey Smith, G., Teschendorff, A., Widschwendter, M., Wong, A., Kuh, D. & Hardy, R., Oct 2017, In: BMJ Open. 7, 10, 11 p., e016708.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

35 Citations (Scopus)

295 Downloads (Pure)

Contrasting the effects of intra-uterine smoking and one-carbon micronutrient exposures on offspring DNA methylation

Richmond, R. & Joubert, B. R., Mar 2017, In: Epigenomics. 9, 3, p. 329-345 17 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

20 Citations (Scopus)

302 Downloads (Pure)

Exploring a causal role of DNA methylation in the relationship between maternal vitamin B12 during pregnancy and child’s IQ at age 8, cognitive performance and educational attainment: a two-step Mendelian randomization study

Caramaschi, D., Sharp, G., Nohr, E., Berryman, K., Lewis, S., Davey Smith, G. & Relton, C., 1 Aug 2017, In: Human Molecular Genetics. 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

46 Citations (Scopus)

481 Downloads (Pure)

Maternal eating disorders affect offspring cord-blood DNA methylation: a prospective study

Kazmi, N., Gaunt, T., Relton, C. & Micali, N., 27 Oct 2017, In: Clinical Epigenetics.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

16 Citations (Scopus)

352 Downloads (Pure)

Statistical and integrative system-level analysis of DNA methylation data

Teschendorff, A. & Relton, C., 13 Nov 2017, (E-pub ahead of print) In: Nature Reviews Genetics. 19 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

211 Citations (Scopus)

848 Downloads (Pure)

The epigenetic clock and physical development during childhood and adolescence: longitudinal analysis from a UK birth cohort

Simpkin, A., Howe, L., Tilling, K., Gaunt, T., Lyttleton, O., McArdle, W., Ring, S., Horvath, S., Davey Smith, G. & Relton, C., Apr 2017, In: International Journal of Epidemiology. 46, 2, p. 549-558 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

108 Citations (Scopus)

323 Downloads (Pure)

2016

Challenges and novel approaches for investigating molecular mediation

Richmond, R. C., Hemani, G., Tilling, K., Davey Smith, G. & Relton, C., 1 Oct 2016, In: Human Molecular Genetics. 25, R2, p. R149-R156 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

102 Citations (Scopus)

400 Downloads (Pure)

(IEU) Epigenetics: Environment, Embodiment & Equality (E4)

Research output

Search results