Longevity-associated BPIFB4 gene therapy for treatment of ischemic disease

Madeddu, Paolo R (Principal Investigator)

Bristol Medical School (THS)

Status	Finished
Effective start/end date	1/08/15 → 31/07/18

Structured keywords

Bristol Heart Institute

5 Article (Academic Journal)
1 Comment/debate (Academic Journal)

Multi-omics analysis of diabetic heart disease in the db/db model reveals potential targets for treatment by a longevity-associated gene
Faulkner, A. R. M., Dang, Z., Avolio, E., Thomas, A. C., Batstone, T. E., Lloyd, G. R., Weber, R., Najdekr, L., Jankevics, A., Dunn, W., Spinetti, G., Vecchione, C., Puca, A. A. & Madeddu, P. R., 21 May 2020, In: Cells. 9, 5, 5 p., 1283.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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8 Citations (Scopus)

73 Downloads (Pure)
Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type-2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway
Dang, Z., Avolio, E., Thomas, A. C., Faulkner, A., Gu, Y., Madeddu, P. R. & al., E., 8 May 2020, In: European Journal of Heart Failure. 22, 9, p. 1568-1581 14 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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22 Citations (Scopus)

44 Downloads (Pure)
Corrigendum to: “The genetics of exceptional longevity identifies new druggable targets for vascular protection and repair” [Pharmacol. Res. 114 (December) (2016) 169–174. doi: 10.1016/j.phrs.2016.10.028. Epub 2016 Nov 3]
Puca, A. A., Spinetti, G., Vono, R., Vecchione, C. & Madeddu, P., May 2017, In: Pharmacological Research. p. 477 1 p.
Research output: Contribution to journal › Comment/debate (Academic Journal)

Open Access
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299 Downloads (Pure)