MagnaPharm

Project Details

Description

The MagnaPharm project, funded under the EU Horizon 2020 'Future and Emerging Technologies' programme, aims to direct polymorphism in pharmaceutical compounds by crystallizing them in high magnetic fields. The ability to direct polymorphism would have a transformative effect on almost all pharmaceutical compounds.

MagnaPharm builds on the discovery by Dr Simon Hall in the School of Chemistry that organic crystal growth can be controlled using magnetic fields. This innovative method will be applied to a range of pharmaceutical compounds, initially targeting 12 of the most high-profile, high-worth generic drugs with the aim of controllably synthesizing the desired polymorph of each (the lowest-energy polymorph and/or most processable form with desired properties).
Alternative titleMagnetic Control of Polymorphism in Pharmaceutical Compounds
StatusFinished
Effective start/end date1/01/1731/12/19

Research Output

  • 2 Article (Academic Journal)
  • 1 Letter (Academic Journal)

DONALD: A 2.5 T wide sample space permanent magnet

Potticary, J., Avery, M. P., Mills, D. & Hall, S. R., Apr 2018, In : HardwareX. 3, p. 39-48 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
  • 1 Citation (Scopus)
    241 Downloads (Pure)

    Thermal Expansion of Carbamazepine: Systematic Crystallographic Measurements Challenge Quantum Chemical Calculations

    Brandenburg, J. G., Potticary, J., Sparkes, H., Price, S. & Hall, S., 7 Sep 2017, In : Journal of Physical Chemistry Letters. 8, 17, p. 4319-4324 6 p.

    Research output: Contribution to journalLetter (Academic Journal)

    Open Access
    File
  • 33 Citations (Scopus)
    257 Downloads (Pure)

    An unforeseen polymorph of coronene by the application of magnetic fields during crystal growth

    Potticary, J., Terry, L. R., Bell, C., Papanikolopoulos, A. N., Christianen, P. C. M., Engelkamp, H., Collins, A. M., Fontanesi, C., Kociok-Köhn, G., Crampin, S., da Como, E. & Hall, S. R., 10 May 2016, In : Nature Communications. 7, 7 p., 11555.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 41 Citations (Scopus)
    342 Downloads (Pure)