MICA:Defining G protein- and arrestin-dependent signalling pathways of biased DOPr agonists and the relevance to their in vivo effects

Kelly, Eamonn P (Principal Investigator)

School of Physiology, Pharmacology & Neuroscience

Status	Finished
Effective start/end date	1/08/16 → 31/10/19
Links	http://gtr.rcuk.ac.uk/projects?ref=MR/N020669/1

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4 Article (Academic Journal)
1 Review article (Academic Journal)

Role of Acetaldehyde in Ethanol Reversal of Tolerance to Morphine-Induced Respiratory Depression in Mice
Hill, R., Conibear, A., Dewey, W., Kelly, E. & Henderson, G., 31 Jan 2022, In: Advances in drug and alcohol research. 1
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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59 Downloads (Pure)
A novel G protein-biased agonist at the δ opioid receptor with analgesic efficacy in models of chronic pain
Conibear, A. E., Asghar, J., Hill, R., Henderson, G., Borbely, E., Tekus, V., Helyes, Z., Palandri, J., Bailey, C., Starke, I., von Mentzer, B., Kendall, D. & Kelly, E., 20 Jan 2020, In: Journal of Pharmacology and Experimental Therapeutics. 372, 2, p. 224-236 13 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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54 Citations (Scopus)

314 Downloads (Pure)
Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor
Gillis, A., Kliewer, A., Kelly, E., Henderson, G., Christie, M. J., Schulz, S. & Canals, M., 1 Dec 2020, In: Trends in Pharmacological Sciences. 41, 12, p. 947-959 13 p.
Research output: Contribution to journal › Review article (Academic Journal) › peer-review

Open Access
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103 Citations (Scopus)

164 Downloads (Pure)