Modular approach to structurally diverse four-membered (spiro)cycles using highly strained precursors

Chemistry

1. Pentane 100%
2. Hexane 80%
3. formation 53%
4. Boronate 40%
5. Iridium 40%
6. Nucleophile 40%
7. Heterocyclic Compound 40%
8. cyclopropanation 40%
9. Chemistry 40%
10. Aziridine 40%
11. Palladium 40%
12. Epoxide 40%
13. epoxidation 40%
14. Ring Opening Reaction 33%
15. Aromatic Structure 30%
16. Metallocene 30%
17. Cycloaddition 26%
18. Catalysis 20%
19. Enantioselectivity 20%
20. Alkene 20%
21. Addition Reaction 20%
22. Constitutional Isomer 20%
23. Tricyclic Hydrocarbon 20%
24. Electrophile 20%
25. dimer 20%
26. Transition Metal 20%
27. Carbene 20%
28. Cyclobutane 20%
29. Imine 20%
30. Sulfoxide 20%
31. Preparative Method 20%
32. Ketone 20%
33. Triflate 20%