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  • 2016

    Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

    Lotchkova, V., Huang, J., Morris, J., Jain, D., Barbieri, C., Walter, K., Min, J., Chen, L., Astle, W. J., Cocca, M., Deelen, P., Elding, H., Farmaki, A.-E., Franklin, C. S., Franberg, M., Gaunt, T., Hofman, A., Jiang, T., Kleber, M. E. & Lachance, G. & 47 others, Luan, J., Malerba, G., Matchan, A., Mead, D., Memari, Y., Ntalla, I., Panoutsopoulou, K., Pazoki, R., Perry, J. R. B., Rivadeneira, F., Sabater-Lleal, M., Sennblad, B., Shin, S.-Y., Southam, L., Traglia, M., van Dijk, F., van Leeuwen, E. M., Zaza, G., Zhang, W., Amin, N., Butterworth, A., Chambers, J. C., Dedoussis, G. V., Dehghan, A., Franco, O. H., Franke, L., Frontini, M., Gambaro, G., Gasparini, P., Hamsten, A., Issacs, A., Kooner, J. S., L Kooperberg, C., Langenberg, C., Marz, W., Scott, R. A., Swertz, M. A., Toniolo, D., Uitterlinden, A. G., van Duijn, C. M., Watkins, H., Zeggini, E., Maurano, M. T., Timpson, N., Reiner, A. P., Auer, P. L. & Soranzo, N., Nov 2016, In: Nature Genetics. 48, 11, p. 1303–1312 12 p.

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  • Exploration of a polygenic risk score for alcohol consumption: A longitudinal analysis from the ALSPAC cohort

    Taylor, M., Simpkin, A., Haycock, P., Dudbridge, F. & Zuccolo, L., 30 Nov 2016, In: PLoS ONE. 11, 11, 15 p., e0167360.

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  • Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

    Tyrrell, J., Richmond, R. C., Palmer, T. M., Feenstra, B., Rangarajan, J., Metrusky, S., Cavadino, A., Paternoster, L., Armstrong, L. L., De Silva, N. M. G., Wood, A. R., Horikoshi, M., Geller, F., Myhre, R., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Painter, J. N., Hottenga, J. J. & Allard, C. & 44 others, Berry, D. J., Bouchard, L., Das, S., Evans, D. M., Hakonarson, H., Hayes, M. G., Heikkinen, J., Hofman, A., Knight, B. A., Lind, P. A., McCarthy, M. I., McMahon, G., Medland, S. E., Melbye, M., Morris, A. P., Nodzenski, M., Reichetzeder, C., Ring, S. M., Sebed, S., Sengpiel, V., Sorensen, T. I. A., Willemsen, G., de Geus, E. J. C., Martin, N. G., Spector, T. D., Power, C., Järvelin, M.-R., Bisgaard, H., Grant, S. F. A., Nohr, E. A., Jaddoe, V., Jacobsson, B., Murray, J. C., Hocher, B., Hattersley, A. T., Scholtens, D. M., Davey Smith, G., Hivert, M.-F., Felix, J. F., Hyppönen, E., Lowe, W. L., Frayling, T. M., Lawlor, D. A. & Freathy, R. M., 15 Mar 2016, In: JAMA - Journal of the American Medical Association. 315, 11, p. 1129-1140 12 p.

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  • Genetic Relationship between Schizophrenia and Nicotine Dependence

    Cotinine meta-analysis group, FTND meta-analysis group , Stiby, A., Hemani, G., Paternoster, L., Timpson, N., Davey Smith, G. & Taylor, M., 10 May 2016, In: Scientific Reports. 6, 10 p., 25671.

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  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Okbay, A., Baselmans, B. M. L., De Neve, J.-E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F. W., Linnér, R. K., Rietveld, C. A., Derringer, J., Gratten, J., Lee, J. J., Liu, J. Z., de Vlaming, R., Ahluwalia, T. S., Buchwald, J., Cavadino, A., Frazier-Wood, A. C., Furlotte, N. A. & Garfield, V. & 31 others, Geisel, M. H., Gonzalez, J. R., Haitjema, S., Karlsson, R., van der Laan, S. W., Ladwig, K.-H., Lahti, J., van der Lee, S. J., Lind, P. A., Liu, T., Matteson, L., Mihailov, E., Miller, M. B., Minica, C. C., Nolte, I. M., Mook-Kanamori, D., van der Most, P. J., Oldmeadow, C., Qian, Y., Raitakari, O., Rawal, R., Stergiakouli, E., Davis, O. S. P., Fatemifar, G., Paternoster, L., Haworth, C. M. A., Sorensen, T., Timpson, N. J., Smith, G. D., Medland, S. E. & LifeLines Cohort Study, Jun 2016, In: Nature Genetics. 48, 6, p. 624-633 13 p.

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  • Genome-wide analysis identifies 12 loci influencing human reproductive behavior

    Barban, N., Jansen, R., De Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., Van Der Laan, S. W., Perry, J. R. B., Kong, A., Ahluwalia, T. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K. & Ayers, K. & 233 others, Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L. F., Bjornsdottir, G., Bonder, M. J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J. E., Turman, C., Concas, M. P., Cordell, H. J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J. F., Fontana, M. A., Franke, L., Gandin, I., Gaskins, A. J., Gieger, C., Gunderson, E. P., Guo, X., Hayward, C., He, C., Hofer, E., Huang, H., Joshi, P. K., Kanoni, S., Karlsson, R., Kiechl, S., Kifley, A., Kluttig, A., Kraft, P., Lagou, V., Lecoeur, C., Lahti, J., Li-Gao, R., Lind, P. A., Liu, T., Makalic, E., Mamasoula, C., Matteson, L., Mbarek, H., McArdle, P. F., McMahon, G., Meddens, S. F. W., Mihailov, E., Miller, M., Missmer, S. A., Monnereau, C., Van Der Most, P. J., Myhre, R., Nalls, M. A., Nutile, T., Kalafati, I. P., Porcu, E., Prokopenko, I., Rajan, K. B., Rich-Edwards, J., Rietveld, C. A., Robino, A., Rose, L. M., Rueedi, R., Ryan, K. A., Saba, Y., Schmidt, D., Smith, J. A., Stolk, L., Streeten, E., Tönjes, A., Thorleifsson, G., Ulivi, S., Wedenoja, J., Wellmann, J., Willeit, P., Yao, J., Yengo, L., Zhao, J. H., Zhao, W., Zhernakova, D. V., Amin, N., Andrews, H., Balkau, B., Barzilai, N., Bergmann, S., Biino, G., Bisgaard, H., Bønnelykke, K., Boomsma, D. I., Buring, J. E., Campbell, H., Cappellani, S., Ciullo, M., Cox, S. R., Cucca, F., Toniolo, D., Davey-Smith, G., Deary, I. J., Dedoussis, G., Deloukas, P., Van Duijn, C. M., De Geus, E. J. C., Eriksson, J. G., Evans, D. A., Faul, J. D., Sala, C. F., Froguel, P., Gasparini, P., Girotto, G., Grabe, H. J., Greiser, K. H., Groenen, P. J. F., De Haan, H. G., Haerting, J., Harris, T. B., Heath, A. C., Heikkilä, K., Hofman, A., Homuth, G., Holliday, E. G., Hopper, J., Hyppönen, E., Jacobsson, B., Jaddoe, V. W. V., Johannesson, M., Jugessur, A., Kähönen, M., Kajantie, E., Kardia, S. L. R., Keavney, B., Kolcic, I., Koponen, P., Kovacs, P., Kronenberg, F., Kutalik, Z., La Bianca, M., Lachance, G., Iacono, W. G., Lai, S., Lehtimäki, T., Liewald, D. C., Lindgren, C. M., Liu, Y., Luben, R., Lucht, M., Luoto, R., Magnus, P., Magnusson, P. K. E., Martin, N. G., McGue, M., McQuillan, R., Medland, S. E., Meisinger, C., Mellström, D., Metspalu, A., Traglia, M., Milani, L., Mitchell, P., Montgomery, G. W., Mook-Kanamori, D., De Mutsert, R., Nohr, E. A., Ohlsson, C., Olsen, J., Ong, K. K., Paternoster, L., Pattie, A., Penninx, B. W. J. H., Perola, M., Peyser, P. A., Pirastu, M., Polasek, O., Power, C., Kaprio, J., Raffel, L. J., Räikkönen, K., Raitakari, O., Ridker, P. M., Ring, S. M., Roll, K., Rudan, I., Ruggiero, D., Rujescu, D., Salomaa, V., Schlessinger, D., Schmidt, H., Schmidt, R., Schupf, N., Smit, J., Sorice, R., Spector, T. D., Starr, J. M., Stöckl, D., Strauch, K., Stumvoll, M., Swertz, M. A., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tung, J. Y., Uitterlinden, A. G., Vaccargiu, S., Viikari, J., Vitart, V., Völzke, H., Vollenweider, P., Vuckovic, D., Waage, J., Wagner, G. G., Wang, J. J., Wareham, N. J., Weir, D. R., Willemsen, G., Willeit, J., Wright, A. F., Zondervan, K. T., Stefansson, K., Krueger, R. F., Lee, J. J., Benjamin, D. J., Cesarini, D., Koellinger, P. D., Den Hoed, M., Snieder, H. & Mills, M. C., Dec 2016, In: Nature Genetics. 48, 12, p. 1462-1472 11 p.

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  • Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

    Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, M. M., Cousminer, D. L., Marsh, J. A. & Lehtimäki, T. & 31 others, Curtin, J. A., Vioque, J., Ahluwalia, T. S., Myhre, R., Price, T. S., Vilor-Tejedor, N., Yengo, L., Grarup, N., Ntalla, I., Ang, W., Atalay, M., Bisgaard, H., Blakemore, A. I., Bonnefond, A., Carstensen, L., Eriksson, J., Flexeder, C., Franke, L., Geller, F., Geserick, M., Hartikainen, A.-L., Haworth, C. M. A., Hirschhorn, J. N., McMahon, G., Murray, C. S., Torrent, M., Ring, S. M., Smith, G. D., Sorensen, T., Timpson, N. J. & Bone Mineral Density in Childhood Study (BMDCS), 15 Jan 2016, In: Human Molecular Genetics. 25, 2, p. 389–403

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    245 Citations (Scopus)

  • Genome-wide associations for birth weight and correlations with adult disease

    Horikoshi, M., Beaumont, R., Day, F., Warrington, N., Kooijman, M., et. al., on behalf of the Early Growth Genetics (ECG) Consortium, Ring, S. M., Hemani, G., McMahon, G., Sorensen, T., Lawlor, D. A., Davey Smith, G., Timpson, N. J., Evans, D., Freathy, R. M. & Paternoster, L., 13 Oct 2016, In: Nature. 538, 7624, p. 248-252 5 p.

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  • Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2

    Ware, J. J., Chen, X., Vink, J. M., Loukola, A., Minica, C., Pool, R., Milaneschi, Y., Mangino, M., Menni, C., Chen, J., Peterson, R. E., Auro, K., Lyytikäinen, L.-P., Wedenoja, J., Stiby, A. I., Hemani, G., Willemsen, G., Hottenga, J. J., Korhonen, T. & Heliövaara, M. & 18 others, Perola, M., Rose, R. J., Paternoster, L., Timpson, N. J., Wassenaar, C. A., Zhu, A. Z. X., Davey Smith, G., T Raitakari, O., Lehtimäki, T., Kähönen, M., Koskinen, S., Spector, T., Penninx, B. W. J. H., Salomaa, V., Boomsma, D. I., Tyndale, R. F., Kaprio, J. & Munafò, M. R., 1 Feb 2016, In: Scientific Reports. 6, 7 p., 20092.

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  • Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

    Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L.-P. & Eriksson, J. & 157 others, Henneman, P., Lahti, J., Tanaka, T., Luan, J., Del Greco M, F., Pasko, D., Renström, F., Willems, S. M., Mahajan, A., Rose, L. M., Guo, X., Liu, Y., Kleber, M. E., Pérusse, L., Gaunt, T., Ahluwalia, T. S., Ju Sung, Y., Ramos, Y. F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B. M., Böhringer, S., I Chen, Y.-D., de Craen, A. J. N., Crosslin, D. R., Dale, C. E., Dastani, Z., Day, F. R., Deelen, J., Delgado, G. E., Demirkan, A., Finucane, F. M., Ford, I., Garcia, M. E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S. E., Havulinna, A. S., Herder, C., Hernandez, D., Hicks, A. A., Hunter, D. J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J.-O., Jenny, N. S., Jørgensen, M. E., Jørgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K.-H., LeDuc, C. A., Lowe, G., Lu, Y., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A. P., Myers, R. H., Männistö, S., Nalls, M. A., Paternoster, L., Peters, A., Pradhan, A. D., Rankinen, T., Rasmussen-Torvik, L. J., Rathmann, W., Rice, T. K., Brent Richards, J., Ridker, P. M., Sattar, N., Savage, D. B., Söderberg, S., Timpson, N. J., Vandenput, L., van Heemst, D., Uh, H.-W., Vohl, M.-C., Walker, M., Wichmann, H.-E., Widén, E., Wood, A. R., Yao, J., Zeller, T., Zhang, Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sorensen, T., Sarzynski, M. A., Rao, D. C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J. G., Heliövaara, M., Knekt, P. B., Koskinen, S., Jula, A., Perola, M., Huupponen, R. K., Viikari, J. S., Kähönen, M., Lehtimäki, T., Raitakari, O. T., Mellström, D., Lorentzon, M., Casas, J. P., Bandinelli, S., März, W., Isaacs, A., van Dijk, K. W., van Duijn, C. M., Harris, T. B., Bouchard, C., Allison, M. A., Chasman, D. I., Ohlsson, C., Lind, L., Scott, R. A., Langenberg, C., Wareham, N. J., Ferrucci, L., Frayling, T. M., Pramstaller, P. P., Borecki, I. B., Waterworth, D. M., Bergmann, S., Waeber, G., Vollenweider, P., Vestergaard, H., Hansen, T., Pedersen, O., Hu, F. B., Eline Slagboom, P., Grallert, H., Spector, T. D., Jukema, J. W., Klein, R. J., Schadt, E. E., Franks, P. W., Lindgren, C. M., Leibel, R. L. & Loos, R. J. F., 1 Feb 2016, In: Nature Communications. 7, 10494.

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  • Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium

    Marinelli, M., Pappa, I., Bustamante, M., Bonilla, C., Suarez, A., Tiesler, C. M., Vilor-Tejedor, N., Zafarmand, M. H., Alvarez-Pedrerol, M., Andersson, S., Bakermans-Kranenburg, M. J., Estivill, X., Evans, D. M., Flexeder, C., Forns, J., Gonzalez, J. R., Guxens, M., Huss, A., Van Ijzendoorn, M. H. & Jaddoe, V. W. V. & 24 others, Julvez, J., Lahti, J., López-Vicente, M., Lopez-Espinosa, M. J., Manz, J., Mileva-Seitz, V. R., Perola, M., Pesonen, A. K., Rivadeneira, F., Salo, P. P., Shahand, S., Schulz, H., Standl, M., Thiering, E., Timpson, N. J., Torrent, M., Uitterlinden, A. G., Smith, G. D., Estarlich, M., Heinrich, J., Räikkönen, K., Vrijkotte, T. G. M., Tiemeier, H. & Sunyer, J., 1 Oct 2016, In: Sleep. 39, 10, p. 1859-1869 11 p.

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  • Incorporating non-coding annotations into rare variant analysis

    Richardson, T., Campbell, C., Timpson, N. & Gaunt, T., 29 Apr 2016, In: PLoS ONE. 11, 4, 15 p.

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  • International GWAS Consortium Identifies Novel Loci Associated with Blood Pressure in Children and Adolescents

    Parmar, P. G., Taal, H. R., Timpson, N. J., Thiering, E., Lehtimäki, T., Marinelli, M., Lind, P. A., Howe, L. D., Verwoert, G., Aalto, V., Uitterlinden, A. G., Briollais, L., Evans, D. M., Wright, M. J., Newnham, J. P., Whitfield, J. B., Lyytikäinen, L.-P., Rivadeneira, F., Boomsma, D. I. & Viikari, J. & 19 others, Gillman, M. W., St Pourcain, B., Hottenga, J.-J., Montgomery, G. W., Hofman, A., Kähönen, M., Martin, N. G., Tobin, M. D., Raitakari, O., Vioque, J., Jaddoe, V. W. V., Jarvelin, M.-R., Beilin, L. J., Heinrich, J., van Duijn, C. M., Pennell, C. E., Lawlor, D. A., Palmer, L. J. & EArly Genetics and Lifecourse Epidemiology Consortium, 11 Mar 2016, In: Circulation: Cardiovascular Genetics.

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    34 Citations (Scopus)

  • Investigating causality in the association between 25(OH)D and schizophrenia

    Taylor, A. E., Burgess, S., Ware, J. J., Gage, S. H., Richards, J. B., Davey Smith, G. & Munafò, M. R., 24 May 2016, In: Scientific Reports. 6, 9 p., 26496.

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  • Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

    Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K.-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G. & Stam, A. H. & 31 others, Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A.-P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J.-J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Kurki, M. I., Kals, M., Stergiakouli, E., Smith, G. D. & International Headache Genetics Consortium, Aug 2016, In: Nature Genetics. 48, 8, p. 856-66 11 p.

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  • Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

    Fan, Q., Verhoeven, V. J. M., Wojciechowski, R., Barathi, V. A., Hysi, P. G., Guggenheim, J. A., Hohn, R., Vitart, V., Khawaja, A. P., Yamashiro, K., Hosseini, S. M., Lehtimaki, T., Lu, Y., Haller, T., Xie, J., Delcourt, C., Pirastu, M., Wedenoja, J., Gharahkhani, P. & Venturini, C. & 134 others, Miyake, M., Hewitt, A. W., Guo, X., Mazur, J., Huffman, J. E., Williams, K. M., Polasek, O., Campbell, H., Rudan, I., Vatavuk, Z., Wilson, J. F., Joshi, P. K., McMahon, G., St Pourcain, B., Evans, D. M., Simpson, C. L., Schwantes-An, T. H., Igo, R. P., Mirshahi, A., Cougnard-Gregoire, A., Bellenguez, C., Blettner, M., Raitakari, O., Kahonen, M., Seppala, I., Zeller, T., Meitinger, T., Ried, J. S., Gieger, C., Portas, L., Van Leeuwen, E. M., Amin, N., Uitterlinden, A. G., Rivadeneira, F., Hofman, A., Vingerling, J. R., Wang, Y. X., Wang, X., Tai-Hui Boh, E., Ikram, M. K., Sabanayagam, C., Gupta, P., Tan, V., Zhou, L., Ho, C. E. H., Lim, W., Beuerman, R. W., Siantar, R., Tai, E. S., Vithana, E., Mihailov, E., Khor, C. C., Hayward, C., Luben, R. N., Foster, P. J., Klein, B. E. K., Klein, R., Wong, H. S., Mitchell, P., Metspalu, A., Aung, T., Young, T. L., He, M., Parssinen, O., Van Duijn, C. M., Jin Wang, J., Williams, C., Jonas, J. B., Teo, Y. Y., MacKey, D. A., Oexle, K., Yoshimura, N., Paterson, A. D., Pfeiffer, N., Wong, T. Y., Baird, P. N., Stambolian, D., Wilson, J. E. B., Cheng, C.-Y., Hammond, C. J., Klaver, C. C. W., Saw, S. M., Rahi, J. S., Korobelnik, J. F., Kemp, J. P., Timpson, N. J., Smith, G. D., Craig, J. E., Burdon, K. P., Fogarty, R. D., Iyengar, S. K., Chew, E., Janmahasatian, S., Martin, N. G., MacGregor, S., Xu, L., Schache, M., Nangia, V., Panda-Jonas, S., Wright, A. F., Fondran, J. R., Lass, J. H., Feng, S., Zhao, J. H., Khaw, K. T., Wareham, N. J., Rantanen, T., Kaprio, J., Pang, C. P., Chen, L. J., Tam, P. O., Jhanji, V., Young, A. L., Doring, A., Raffel, L. J., Cotch, M. F., Li, X., Yip, S. P., Yap, M. K. H., Biino, G., Vaccargiu, S., Fossarello, M., Fleck, B., Yazar, S., Tideman, J. W. L., Tedja, M., Deangelis, M. M., Morrison, M., Farrer, L., Zhou, X., Chen, W., Mizuki, N., Meguro, A. & Makela, K. M., 6 Apr 2016, In: Nature Communications. 7, 12 p., 11008.

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  • Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

    van den Berg, S. M., de Moor, M. H. M., Verweij, K. J. H., Krueger, R. F., Luciano, M., Arias Vasquez, A., Matteson, L. K., Derringer, J., Esko, T., Amin, N., Gordon, S. D., Hansell, N. K., Hart, A. B., Seppälä, I., Huffman, J. E., Konte, B., Lahti, J., Lee, M., Miller, M. & Nutile, T. & 31 others, Tanaka, T., Teumer, A., Viktorin, A., Wedenoja, J., Abdellaoui, A., Abecasis, G. R., Adkins, D. E., Agrawal, A., Allik, J., Appel, K., Bigdeli, T. B., Busonero, F., Campbell, H., Costa, P. T., Smith, G. D., Davies, G., de Wit, H., Ding, J., Engelhardt, B. E., Eriksson, J. G., Fedko, I. O., Ferrucci, L., Franke, B., Giegling, I., Grucza, R., Kemp, J. P., Medland, S. E., St Pourcain, B., Timpson, N. J., Evans, D. M. & Generation Scotland, Mar 2016, In: Behavior Genetics. 46, 2, p. 170-182 13 p.

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  • Metabolic characterisation of a rare genetic variation within APOC3 and its lipoprotein lipase independent effects

    Drenos, F., Davey Smith, G., Ala-Korpela, M., Kettunen, J., Würtz, P., Soininen, P., Kangas, A. J., Dale, C., Lawlor, D., Gaunt, T., Casas, J.-P. & Timpson, N., Jun 2016, In: Circulation: Cardiovascular Genetics. 9, 3, p. 231-239 9 p.

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  • Microbiological assessment of aerosol generated during debond of fixed orthodontic appliances

    Dawson, M., Soro, V., Dymock, D., Price, R., Griffiths, H., Dudding, T., Sandy, J. R. & Ireland, A. J., Nov 2016, In: American Journal of Orthodontics and Dentofacial Orthopedics. 150, 5, p. 831-838 8 p.

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  • Obesity and Multiple Sclerosis: A Mendelian Randomization Study

    Mokry, L. E., Ross, S., Timpson, N., Sawcer, S. J., Davey Smith, G. & Richards, J. B., 28 Jun 2016, In: PLoS Medicine. 13, 6, 16 p., e1002053.

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  • Paradoxical relationship between body mass index and thyroid hormone levels: a study using Mendelian Randomization

    Taylor, P. N., Richmond, R., Davies, N., Sayers, A., Stevenson, K., Woltersdorf, W., Taylor, A., Groom, A., Northstone, K., Ring, S., Okosieme, O., Rees, A., Nitsch, D., Williams, G. R., Smith, G. D., Gregory, J. W., Timpson, N. J., Tobias, J. H. & Dayan, C. M., 1 Feb 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 2, jc20153505.

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    42 Citations (Scopus)

  • The CHRNA5-A3-B4 gene cluster and smoking: From discovery to therapeutics

    Lassi, G., Taylor, A., Timpson, N., J Kenny, P., J Mather, R., Eisen, T. & Munafo, M., Dec 2016, In: Trends in Neurosciences. 39, 12, p. 851–861 11 p.

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  • The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A.-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K. & Shah, S. & 31 others, Kleber, M. E., Guo, X., Lyytikäinen, L.-P., Fava, C., Eriksson, N., Nolte, I. M., Magnusson, P. K., Salfati, E. L., Rallidis, L. S., Theusch, E., Smith, A. J. P., Folkersen, L., Witkowska, K., Pers, T. H., Joehanes, R., Drenos, F., Eicher, J. D., Evans, A., Hunt, S. C., Kim, Y. K., Kivimaki, M., Kuh, D., Lin, L., Tobin, M. D., Wain, L. V., Wilson, J. F., Cooper, R. S., Wong, A., Kumari, M., Palmer, C. N. A. & CHARGE-EchoGen Consortium, Oct 2016, In: Nature Genetics. 48, 10, p. 1171-1184 14 p.

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    317 Citations (Scopus)

  • The range of peripapillary retinal nerve fibre layer and optic disc parameters, in children aged up to but not including 18 years of age who were born prematurely: protocol for a systematic review

    Creavin, A. L., Williams, C. E. M., Tilling, K., Luyt, K., Timpson, N. & Higgins, J. P. T., 30 Sept 2016, In: Systematic Reviews. 5, 4 p., 144.

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  • Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A. & Harakalova, M. & 190 others, Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Havulinna, A. S., Zhang, H., Donnelly, L. A., Groves, C. J., Rayner, N. W., Neville, M. J., Robertson, N. R., Yiorkas, A. M., Herzig, K. H., Kajantie, E., Zhang, W., Willems, S. M., Lannfelt, L., Malerba, G., Soranzo, N., Trabetti, E., Verweij, N., Evangelou, E., Moayyeri, A., Vergnaud, A. C., Nelson, C. P., Poveda, A., Varga, T. V., Caslake, M., De Craen, A. J. M., Trompet, S., Luan, J., Scott, R. A., Harris, S. E., Liewald, D. C. M., Marioni, R., Menni, C., Farmaki, A. E., Hallmans, G., Renström, F., Huffman, J. E., Hassinen, M., Burgess, S., Vasan, R. S., Felix, J. F., Uria-Nickelsen, M., Malarstig, A., Reilly, D. F., Hoek, M., Vogt, T. F., Lin, H., Lieb, W., Traylor, M., Markus, H. S., Highland, H. M., Justice, A. E., Marouli, E., Lindström, J., Uusitupa, M., Komulainen, P., Lakka, T. A., Rauramaa, R., Polasek, O., Rudan, I., Rolandsson, O., Franks, P. W., Dedoussis, G., Spector, T. D., Jousilahti, P., Männistö, S., Deary, I. J., Starr, J. M., Langenberg, C., Wareham, N. J., Brown, M. J., Dominiczak, A. F., Connell, J. M., Jukema, J. W., Sattar, N., Ford, I., Packard, C. J., Esko, T., Mägi, R., Metspalu, A., De Boer, R. A., Van Der Meer, P., Van Der Harst, P., Gambaro, G., Ingelsson, E., Lind, L., De Bakker, P. I. W., Numans, M. E., Brandslund, I., Christensen, C., Petersen, E. R. B., Korpi-Hyövälti, E., Oksa, H., Chambers, J. C., Kooner, J. S., Blakemore, A. I. F., Franks, S., Jarvelin, M. R., Husemoen, L. L., Linneberg, A., Skaaby, T., Thuesen, B., Karpe, F., Tuomilehto, J., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., Holmen, O. L., Hveem, K., Willer, C. J., Tuomi, T., Groop, L., Käräjämäki, A., Palotie, A., Ripatti, S., Salomaa, V., Alam, D. S., Majumder, A. A. S., Di Angelantonio, E., Chowdhury, R., McCarthy, M. I., Poulter, N., Stanton, A. V., Sever, P., Amouyel, P., Arveiler, D., Blankenberg, S., Ferrières, J., Kee, F., Kuulasmaa, K., Müller-Nurasyid, M., Veronesi, G., Virtamo, J., Deloukas, P., Elliott, P., Zeggini, E., Kathiresan, S., Melander, O., Kuusisto, J., Laakso, M., Padmanabhan, S., Porteous, D. J., Hayward, C., Scotland, G., Collins, F. S., Mohlke, K. L., Hansen, T., Pedersen, O., Boehnke, M., Stringham, H. M., Frossard, P., Newton-Cheh, C., Tobin, M. D., Nordestgaard, B. G., Caulfield, M. J., Mahajan, A., Morris, A. P., Tomaszewski, M., Samani, N. J., Saleheen, D., Asselbergs, F. W., Lindgren, C. M., Danesh, J., Wain, L. V., Butterworth, A. S., Howson, J. M. M. & Munroe, P. B., 1 Oct 2016, In: Nature Genetics. 48, 10, p. 1151-1161 11 p.

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  • Triangulating meta-analyses: the example of the serotonin transporter gene, stressful life events and major depression

    Taylor, A. E. & Munafò, M. R., 31 May 2016, In: BMC Psychology. 4, 1, 9 p., 23.

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  • 2015

    A genome-wide approach to children's aggressive behavior: The EAGLE consortium

    Pappa, I., Benke, K., Cavadino, A., Hakulinen, C., Nivard, M. G., Nolte, I. M., Tiesler, C. M. T., Bakermans-Kranenburg, M. J., Geoffroy, M.-C., Grallert, H., Groen-Blokhuis, M. M., Hudziak, J. J., Keltikangas-Järvinen, L., Mileva-Seitz, V. R., Motazedi, E., Power, C., Raitakari, O. T., Ring, S. M., Rivadeneira, F. & Rodriguez, A. & 17 others, Scheet, P. A., Seppälä, I., Snieder, H., Standl, M., Thiering, E., Veenstra, R., Velders, F. P., Whitehouse, A. J. O., Heinrich, J., Hypponen, E., Lehtimäki, T., Middeldorp, C. M., Oldehinkel, A. J., Pennell, C. E., Boomsma, D. I., Tiemeier, H. & Timpson, N., 18 Jun 2015, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics.

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    129 Citations (Scopus)

  • A genome-wide association study of body mass index across early life and childhood

    Warrington, N. M., Howe, L. D., Paternoster, L., Kaakinen, M., Herrala, S., Huikari, V., Wu, Y. Y., Kemp, J. P., Timpson, N. J., Pourcain, B. S., Davey Smith, G., Tilling, K., Jarvelin, M.-R., Pennell, C. E., Evans, D. M., Lawlor, D. A., Briollais, L. & Palmer, L. J., 7 May 2015, In: International Journal of Epidemiology. 44, 2, p. 700-712 12 p.

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    102 Citations (Scopus)

  • An interactive genome browser of association results from the UK10K cohorts project

    Geihs, M., Yan, Y., Walter, K., Huang, J., Memari, Y., Min, J. L., Mead, D., Hubbard, T. J., Timpson, N. J., Down, T. A., Soranzo, N. & UK10K Consortium, 15 Dec 2015, In: Bioinformatics. 31, 24, p. 4029-31 3 p.

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    9 Citations (Scopus)

  • A novel common variant in DCST2 is associated with length in early life and height in adulthood

    van der Valk, R. J. P., Kreiner-Møller, E., Kooijman, M. N., Guxens, M., Stergiakouli, E., Sääf, A., Bradfield, J. P., Geller, F., Hayes, M. G., Cousminer, D. L., Körner, A., Thiering, E., Curtin, J. A., Myhre, R., Huikari, V., Joro, R., Kerkhof, M., Warrington, N. M., Pitkänen, N. & Ntalla, I. & 31 others, Horikoshi, M., Veijola, R., Freathy, R. M., Teo, Y.-Y., Barton, S. J., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Davey Smith, G., Bergström, A., Kull, I., Hakonarson, H., Mentch, F. D., Bisgaard, H., Chawes, B., Stokholm, J., Waage, J., Eriksen, P., Sevelsted, A., Melbye, M., van Duijn, C. M., Medina-Gomez, C., Hofman, A., de Jongste, J. C., Taal, H. R., Uitterlinden, A. G., Murray, C. S., Holloway, J. W., Timpson, N. J. & Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, 15 Feb 2015, In: Human Molecular Genetics. 24, 4, p. 1155-1168 14 p.

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    82 Citations (Scopus)

  • Blood pressure and mortality: using offspring blood pressure as an instrument for own blood pressure in the HUNT study

    Wade, K. H., Carslake, D., Nilsen, T. I. L., Timpson, N., Davey Smith, G. & Romundstad, P. R., 22 Jul 2015, In: Scientific Reports. 5, 12399.

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  • Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis

    Freitag, D., Butterworth, A. S., Willeit, P., Howson, J. M. M., Burgess, S., Kaptoge, S., Young, R., Ho, W. K., Wood, A. M., Sweeting, M., Spackman, S., Staley, J. R., Ramond, A., Harshfield, E., Nielsen, S. F., Grande, P., Lange, L. A., Bown, M. J., Jones, G. T. & Scott, R. A. & 133 others, Bevan, S., Porcu, E., Thorleifsson, G., Zeng, L., Kessler, T., Nikpay, M., Do, R., Zhang, W., Hopewell, J. C., Kleber, M., Delgado, G. E., Nelson, C. P., Goel, A., Bis, J. C., Dehghan, A., Ligthart, S., Smith, A. V., Qu, L., van 't Hof, F. N. G., de Bakker, P. I. W., Baas, A. F., van Rij, A., Tromp, G., Kuivaniemi, H., Ritchie, M. D., Verma, S. S., Crawford, D. C., Malinowski, J., de Andrade, M., Kullo, I. J., Peissig, P. L., McCarty, C. A., Böttinger, E. P., Gottesman, O., Crosslin, D. R., Carrell, D. S., Rasmussen-Torvik, L. J., Pacheco, J. A., Huang, J., Timpson, N. J., Kettunen, J., Ala-Korpela, M., Mitchell, G. F., Parsa, A., Wilkinson, I. B., Gorski, M., Li, Y., Franceschini, N., Keller, M. F., Ganesh, S. K., Langefeld, C. D., Bruijn, L., Brown, M. A., Evans, D. M., Baltic, S., Ferreira, M. A., Baurecht, H., Weidinger, S., Franke, A., Lubitz, S. A., Müller-Nurasyid, M., Felix, J. F., Smith, N. L., Sudman, M., Thompson, S. D., Zeggini, E., Panoutsopoulou, K., Nalls, M. A., Singleton, A., Polychronakos, C., Bradfield, J. P., Hakonarson, H., Easton, D. F., Thompson, D., Tomlinson, I. P., Dunlop, M., Hemminki, K., Morgan, G., Eisen, T., Goldschmidt, H., Allan, J. M., Henrion, M., Whiffin, N., Wang, Y., Chubb, D., Iles, M. M., Bishop, D. T., Law, M. H., Hayward, N. K., Luo, Y., Nejentsev, S., Barbalic, M., Crossman, D., Sanna, S., Soranzo, N., Markus, H. S., Wareham, N. J., Rader, D. J., Reilly, M., Assimes, T., Harris, T. B., Hofman, A., Franco, O. H., Gudnason, V., Tracy, R., Psaty, B. M., Farrall, M., Watkins, H., Hall, A. S., Samani, N. J., März, W., Clarke, R., Collins, R., Kooner, J. S., Chambers, J. C., Kathiresan, S., McPherson, R., Erdmann, J., Kastrati, A., Schunkert, H., Stefánsson, K., Thorsteinsdottir, U., Walston, J. D., Tybjærg-Hansen, A., Alam, D. S., Al Shafi Majumder, A., Angelantonio, E. D., Chowdhury, R., Nordestgaard, B. G., Saleheen, D., Thompson, S. G., Danesh, J. & Houlston, R. S., 1 Apr 2015, In: Lancet Diabetes and Endocrinology. 3, 4, p. 243-253 11 p.

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    110 Citations (Scopus)

  • Copy number variations and cognitive phenotypes in unselected populations

    Männik, K., Mägi, R., Macé, A., Cole, B., Guyatt, A. L., Shihab, H. A., Maillard, A. M., Alavere, H., Kolk, A., Reigo, A., Mihailov, E., Leitsalu, L., Ferreira, A.-M., Nõukas, M., Teumer, A., Salvi, E., Cusi, D., McGue, M., Iacono, W. G. & Gaunt, T. R. & 7 others, Beckmann, J. S., Jacquemont, S., Kutalik, Z., Pankratz, N., Timpson, N., Metspalu, A. & Reymond, A., 26 May 2015, In: JAMA - Journal of the American Medical Association. 313, 20, p. 2044-2054 11 p.

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    122 Citations (Scopus)

  • Does smoking reduction worsen mental health? A comparison of two observational approaches

    Taylor, G. M. J., Taylor, A. E., Munafo, M. R., McNeill, A. & Aveyard, P., 15 May 2015, In: BMJ Open. 5, 5, 7 p., e007812.

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  • Early cannabis use, polygenic risk score for schizophrenia, and brain maturation in adolescence

    French, L., Gray, C., Leonard, G., Perron, M., Pike, G. B., Richer, L., Séguin, J. R., Veillette, S., Evans, C. J., Artiges, E., Banaschewski, T., Bokde, A. W. L., Bromberg, U., Bruehl, R., Buchel, C., Cattrell, A., Conrod, P. J., Flor, H., Frouin, V. & Gallinat, J. & 18 others, Garavan, H., Gowland, P., Heinz, A., Lemaitre, H., Martinot, J. L., Nees, F., Orfanos, D. P., Pangelinan, M. M., Poustka, L., Rietschel, M., Smolka, M. N., Walter, H., Whelan, R., Timpson, N. J., Schumann, G., Smith, G. D., Pausova, Z. & Paus, T., 1 Oct 2015, In: JAMA Psychiatry. 72, 10, p. 1002-1011 10 p.

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    136 Citations (Scopus)

  • Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium

    Linneberg, A., Jacobsen, R. K., Skaaby, T., Taylor, A. E., Fluharty, M. E., Jeppesen, J. L., Bjorngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R. E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T. S., Wannamethee, S. G., Lahti, J. & Raikkonen, K. & 40 others, Palotie, A., Wong, A., Dalgård, C., Ford, I., Ben-Shlomo, Y., Christiansen, L., Kyvik, K. O., Kuh, D. J. L., Eriksson, J. G., Whincup, P. H., Mbarek, H., De Geus, E. J. C., Vink, J. M., Boomsma, D. I., Smith, G. D., Lawlor, D. A., Kisialiou, A., McConnachie, A., Padmanabhan, S., Jukema, J. W., Power, C., Hypponen, E., Preisig, M., Waeber, G., Vollenweider, P., Korhonen, T., Laatikainen, T., Salomaa, V., Kaprio, J., Kivimaki, M. J., Smith, B. H., Hayward, C., Sorensen, T., Thuesen, B. H., Sattar, N., Morris, R. W., Romundstad, P. R., Munafò, M. R., Jarvelin, M. R. & Husemoen, L. L. N., 1 Dec 2015, In: Circulation: Cardiovascular Genetics. 8, 6, p. 832-841 10 p.

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  • Exploring causal associations of alcohol with cardiovascular and metabolic risk factors in a Chinese population using Mendelian randomization analysis

    Taylor, A. E., Lu, F., Carslake, D. J., Hu, Z., Qian, Y., Liu, S., Chen, J., Chen, H. & Davey Smith, G., 14 Sept 2015, In: Scientific Reports. 5, 6 p., 14005.

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  • Exploring possible epigenetic mediation of early-life environmental exposures on adiposity and obesity development

    Richmond, R. C., Timpson, N. J. & Sorensen, T., Aug 2015, In: International Journal of Epidemiology. 44, 4, p. 1191-8 8 p.

    Research output: Contribution to journal › Article (Academic Journal) › peer-review

    23 Citations (Scopus)

  • Genetics, sleep and memory: a recall-by-genotype study of ZNF804A variants and sleep neurophysiology

    Hellmich, C., Durant, C. F., Timpson, N. J., Bartsch, U., Corbin, L. J. & Jones, M. W., 27 Oct 2015, In: BMC Medical Genetics. 16, 1, 8 p., 96.

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    7 Citations (Scopus)
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  • Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

    Li, Q., Wojciechowski, R., Simpson, C. L., Hysi, P. G., Verhoeven, V. J. M., Höhn, R., Vitart, V., Hewitt, A. W., Oexle, K., Mäkelä, K.-M., MacGregor, S., Pirastu, M., Fan, Q., Cheng, C.-Y., St Pourcain, B., McMahon, G., Kemp, J. P., Northstone, K., Rahi, J. S. & Cumberland, P. M. & 28 others, Martin, N. G., Sanfilippo, P. G., Lu, Y., Wang, Y. X., Hayward, C., Polašek, O., Campbell, H., Bencic, G., Wedenoja, J., Zeller, T., Schillert, A., Mirshahi, A., Lackner, K., Yip, S. P., Yap, M. K. H., Ried, J. S., Gieger, C., Murgia, F., Fleck, B., Yazar, S., Vingerling, J. R., Timpson, N. J., Evans, D. M., Mitchell, P., Williams, C., Paterson, A. D., Guggenheim, J. A. & The CREAM Consortium, Feb 2015, In: Human Genetics. 134, 2, p. 131-46 16 p.

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    24 Citations (Scopus)

  • Genome-wide association study identifies SNPs in the MHC class II loci that are associated with self-reported history of whooping cough

    McMahon, G., Ring, S. M., Davey-Smith, G. & Timpson, N. J., 15 Oct 2015, In: Human Molecular Genetics. 24, 20, p. 5930-9 10 p.

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    7 Citations (Scopus)

  • Genome-wide association study of blood lead shows multiple associations near ALAD

    Warrington, N. M., Zhu, G., Dy, V., Heath, A. C., Madden, P. A. F., Hemani, G., Kemp, J. P., Mcmahon, G., St Pourcain, B., Timpson, N. J., Taylor, C. M., Golding, J., Lawlor, D. A., Steer, C., Montgomery, G. W., Martin, N. G., Davey Smith, G., Evans, D. M. & Whitfield, J. B., 1 Jul 2015, In: Human Molecular Genetics. 24, 13, p. 3871–3879 9 p.

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    30 Citations (Scopus)

  • Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

    Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L. & Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M.-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sorensen, T., Munafò, M. R. & Sattar, N., 11 Aug 2015, In: BMJ Open. 5, 8, 12 p., e008808.

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    49 Citations (Scopus)
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  • Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence

    St Pourcain, B., Haworth, C. M. A., Davis, O. S. P., Wang, K., Timpson, N. J., Evans, D. M., Kemp, J. P., Ronald, A., Price, T., Meaburn, E., Ring, S. M., Golding, J., Hakonarson, H., Plomin, R. & Davey Smith, G., Jun 2015, In: Human Genetics. 134, 6, p. 539-551 13 p.

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    15 Citations (Scopus)
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  • HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight evidence from genetic analysis and randomised trials

    Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K. & Palmen, J. & 113 others, Howard, P., Cooper, J. A., Drenos, F., Li, Y. R., Lowe, G., Gallacher, J., Stewart, M. C. W., Tzoulaki, I., Buxbaum, S. G., Van Der A, D. L., Forouhi, N. G., Onland-Moret, N. C., Van Der Schouw, Y. T., Schnabel, R. B., Hubacek, J. A., Kubinova, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S., Baldassarre, D., Sennblad, B., Tremoli, E., De Faire, U., Veglia, F., Ford, I., Jukema, J. W., Westendorp, R. G. J., De Borst, G. J., De Jong, P. A., Algra, A., Spiering, W., Der Zee, A. H. M. V., Klungel, O. H., De Boer, A., Doevendans, P. A., Eaton, C. B., Robinson, J. G., Duggan, D., Kjekshus, J., Downs, J. R., Gotto, A. M., Keech, A. C., Marchioli, R., Tognoni, G., Sever, P. S., Poulter, N. R., Waters, D. D., Pedersen, T. R., Amarenco, P., Nakamura, H., McMurray, J. J. V., Lewsey, J. D., Chasman, D. I., Ridker, P. M., Maggioni, A. P., Tavazzi, L., Ray, K. K., Seshasai, S. R. K., Manson, J. E., Price, J. F., Whincup, P. H., Morris, R. W., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Schreiner, P. J., Fornage, M., Siscovick, D. S., Cushman, M., Kumari, M., Wareham, N. J., Verschuren, W. M. M., Redline, S., Patel, S. R., Whittaker, J. C., Hamsten, A., Delaney, J. A., Dale, C., Gaunt, T. R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B. A., Van Der Harst, P., Brunner, E. J., Tybjaerg-Hansen, A., Marmot, M. G., Krauss, R. M., Tsai, M., Coresh, J., Hoogeveen, R. C., Psaty, B. M., Lange, L. A., Hakonarson, H., Dudbridge, F., Humphries, S. E., Talmud, P. J., Kivimäki, M., Timpson, N. J., Langenberg, C., Asselbergs, F. W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J. G., Reiner, A. P., Keating, B. J., Hingorani, A. D. & Sattar, N., 24 Jan 2015, In: Lancet. 385, 9965, p. 351-361 11 p.

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    549 Citations (Scopus)

  • Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

    Huang, J., Howie, B., McCarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H.-F., Gambaro, G., Richards, J. B., Durbin, R., Timpson, N. J., Marchini, J., Soranzo, N. & UK10K Consortium, 2015, In: Nature Communications. 6, p. 8111

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    231 Citations (Scopus)

  • Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

    de Moor, M. H. M., van den Berg, S. M., Verweij, K. J. H., Krueger, R. F., Luciano, M., Arias Vasquez, A., Matteson, L. K., Derringer, J., Esko, T., Amin, N., Gordon, S. D., Hansell, N. K., Hart, A. B., Seppälä, I., Huffman, J. E., Konte, B., Lahti, J., Lee, M., Miller, M. & Nutile, T. & 30 others, Tanaka, T., Teumer, A., Viktorin, A., Wedenoja, J., Abecasis, G. R., Adkins, D. E., Agrawal, A., Allik, J., Appel, K., Bigdeli, T. B., Busonero, F., Campbell, H., Costa, P. T., Davey Smith, G., Davies, G., de Wit, H., Ding, J., Engelhardt, B. E., Eriksson, J. G., Fedko, I. O., Ferrucci, L., Franke, B., Giegling, I., Grucza, R., Kemp, J. P., Medland, S. E., St Pourcain, B., Timpson, N. J., Evans, D. M. & Genetics of Personality Consortium, 20 May 2015, In: JAMA Psychiatry.

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    219 Citations (Scopus)

  • Mosaic structural variation in children with developmental disorders

    King, D., Jones, W., Crow, Y., Dominiczak, A., Foster, N., Gaunt, T. R., Harris, J., Hellens, S., Homfray, T., Innes, J., Jones, E., Joss, S., Kulkarni, A., Mansour, S., Morris, A., Parker, M., Porteous, D., Shihab, H. A., Smith, B. & Tatton-Brown, K. & 8 others, Tolmie, J., Trzaskowski, M., Vasudevan, P., Wakeling, E., Wright, M., Plomin, R., Timpson, N. J. & Hurles, M., May 2015, In: Human Molecular Genetics. 24, 10, p. 2733–2745

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    47 Citations (Scopus)

  • MR-PheWAS: Hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization

    Millard, L. A. C., Davies, N. M., Timpson, N. J., Tilling, K. M., Flach, P. A. & Davey Smith, G., 16 Nov 2015, In: Scientific Reports. 5, 17 p., 16645.

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  • Prenatal exposure to maternal cigarette smoking and DNA methylation: epigenome-wide association in a discovery sample of adolescents and replication in an independent cohort at birth through 17 years of age

    Lee, K. W. K., Richmond, R., Hu, P., French, L., Shin, J., Bourdon, C., Reischl, E., Waldenberger, M., Zeilinger, S., Gaunt, T., McArdle, W., Ring, S., Woodward, G., Bouchard, L., Gaudet, D., Smith, G. D., Relton, C., Paus, T. & Pausova, Z., 1 Jan 2015, In: Environmental Health Perspectives. 123, 2, p. 193-199 7 p.

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    156 Citations (Scopus)