Project Details
Description
What are we investigating and why?
We urgently need better evidence about how our experiences before birth might influence our long-term health. Most research in this area has focused on the lifestyles of pregnant mothers, but the evidence is patchy and health advice offered to pregnant women can be confusing and inconsistent. More recent research suggests that a father's behaviour can influence the health of his unborn children, but very little public health advice is currently offered to fathers-to-be. EPoCH is addressing the urgent need for better quality scientific evidence on how the health behaviours of both mums and dads in the prenatal period might affect the health of their children.
How?
We're combining existing data on hundreds of thousands of people from several large European studies. Using this information, we're studying whether parents' smoking, drinking alcohol, drinking caffeine, eating junk food and keeping physically active are causally related to lots of different measures of health and development in children, such as weight, height, body fat, behaviour, and how well the children do at school. Where it looks like there's a causal effect, we're also trying to work out whether it's the mum's lifestyle, the dad's or the combination that's most important.
What do we want to achieve?
Our findings will be vital for producing robust, scientific evidence that can be used to develop clearer, less misleading, more effective health advice to both parents in the important prenatal period. We hope this will help maximise the health of the whole family.
We urgently need better evidence about how our experiences before birth might influence our long-term health. Most research in this area has focused on the lifestyles of pregnant mothers, but the evidence is patchy and health advice offered to pregnant women can be confusing and inconsistent. More recent research suggests that a father's behaviour can influence the health of his unborn children, but very little public health advice is currently offered to fathers-to-be. EPoCH is addressing the urgent need for better quality scientific evidence on how the health behaviours of both mums and dads in the prenatal period might affect the health of their children.
How?
We're combining existing data on hundreds of thousands of people from several large European studies. Using this information, we're studying whether parents' smoking, drinking alcohol, drinking caffeine, eating junk food and keeping physically active are causally related to lots of different measures of health and development in children, such as weight, height, body fat, behaviour, and how well the children do at school. Where it looks like there's a causal effect, we're also trying to work out whether it's the mum's lifestyle, the dad's or the combination that's most important.
What do we want to achieve?
Our findings will be vital for producing robust, scientific evidence that can be used to develop clearer, less misleading, more effective health advice to both parents in the important prenatal period. We hope this will help maximise the health of the whole family.
| Alternative title | Exploring Prenatal influences on Childhood Health |
|---|---|
| Acronym | EPoCH |
| Status | Finished |
| Effective start/end date | 3/06/19 → 30/09/22 |
Research Groups and Themes
- ALSPAC
- Bristol Population Health Science Institute
- Physical and Mental Health
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Research output
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Challenges in using data on fathers/partners to study prenatal exposures and offspring health
Easey, K. E., Gkatzionis, A., Millard, L. A. C., Tilling, K. M., Lawlor, D. A. & Sharp, G. C., 28 Oct 2024, In: Journal of Developmental Origins of Health and Disease. 15, p. e25 9 p., e25.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Maternal age is related to offspring DNA methylation: a meta-analysis of results from the PACE consortium
Yeung, E., Biedrzycki, R., Gómez Herrera, L., Issarapu, P., Dou, J. F., Marques, I. F., Mansuri, S., Page, C., Harbs, J., Khodasevich, D., Poisel, E., Niu, Z., Allard, C., Casey, E., Morales Berstein, F., Mancano, G., Elliott, H. R., Richmond, R., He, Y. & Ronkainen, J. & 38 others, , 1 Aug 2024, In: Aging Cell. 23, 8, 16 p., e14194.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation
et al., Jun 2021, In: Molecular Psychiatry. 26, 6, p. 1832-1845 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile26 Citations (Scopus)111 Downloads (Pure)