THE USE OF HUMAN-MURINE CFTR CHIMERAS TO INVESTIGATE THE COUPLING OF PERMEATION AND GATING IN THE CFTR CHLORIDE CHANNEL

Status	Finished
Effective start/end date	1/05/05 → 1/05/08

Revertant mutants modify, but do not rescue, the gating defect of the cystic fibrosis mutant G551D-CFTR
Xu, Z., Pissarra, L. S., Farinha, C. M., Liu, J., Cai, Z., Thibodeau, P. H., Amaral, M. D. & Sheppard, D. N., 1 May 2014, In: Journal of Physiology. 592, 9, p. 1931-1947 17 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
20 Citations (Scopus)
Acute inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel by thyroid hormones involves multiple mechanisms
Cai, Z., Li, H., Chen, J.-H. & Sheppard, D. N., Oct 2013, In: AJP - Cell Physiology. 305, 8, p. C817-C828 12 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
11 Citations (Scopus)
Folding and rescue of a cystic fibrosis transmembrane conductance regulator trafficking mutant identified using human-murine chimeric proteins
Da Paula, A., Sousa, M., Xu, Z., Dawson, E., Boyd, A., Sheppard, D. & Amaral, M., Aug 2010, In: Journal of Biological Chemistry. 285, p. 27033 - 27044 12 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
6 Citations (Scopus)

Project Details