Understanding Programming in Highly Reducing Iterative Fungal Polyketide Synthases - a Structural and Mechanistic Approach

Simpson, Thomas J (Principal Investigator)

Status	Finished
Effective start/end date	1/07/11 → 1/01/15

Structured keywords

BCS and TECS CDTs
BrisSynBio
Bristol BioDesign Institute

10 Article (Academic Journal)

In vitro kinetic study of the squalestatin tetraketide synthase dehydratase reveals the stereochemical course of a fungal highly reducing polyketide synthase
Liddle, E., Scott, A., Han, L. C., Ivison, D., Simpson, T. J., Willis, C. L. & Cox, R. J., 4 Feb 2017, In: Chemical Communications. 53, 10, p. 1727-1730 4 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
File
12 Citations (Scopus)

336 Downloads (Pure)
Recognition of extended linear and cyclised polyketide mimics by a Type II acyl carrier protein
Dong, X., Bailey, C., Williams, C., Crosby, J., Simpson, T., Willis, C. & Crump, M., 1 Mar 2016, In: Chemical Science. 7, 3, p. 1779-1785 7 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
File
8 Citations (Scopus)

324 Downloads (Pure)
Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae
Song, Z., Bakeer, W. I. M. M., Marshall, J. W., Yakasai, A. A., Mohd Khalid, R., Collemare, J., Skellam, E., Tharreau, D., Lebrun, M. H., Lazarus, C. M., Bailey, A. M., Simpson, T. J. & Cox, R. J., 1 Aug 2015, In: Chemical Science. 6, 8, p. 4837-4845 9 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
File
55 Citations (Scopus)

435 Downloads (Pure)